Marijuana Basics and Variations

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Questions and Answers

What is Cannabidiol primarily used for in medical treatments?

  • To induce sleep in chronic insomnia patients
  • To alleviate loss of appetite in AIDS patients (correct)
  • To reduce inflammation in joints
  • To enhance cognitive function

How can Cannabidiol be administered?

  • Orally as oils, capsules, edibles, or tinctures (correct)
  • Sublingually as a spray
  • Only intravenously
  • By inhalation through traditional cigarettes

Which alternative method of consuming marijuana is highlighted as a new trend among teens?

  • Homemade edibles
  • Traditional cigars or blunts
  • Bongs with water filtration
  • Vaporizers like the 'G-Pen' (correct)

What is a common outcome of overstimulating cannabinoid receptors in the brain?

<p>Feeling of euphoria or a 'high' (B)</p>
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What effects does THC have on the brain?

<p>It affects memory, pleasure, coordination, and concentration (A)</p>
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What is cannabinoid hyperemesis syndrome (CHS) primarily characterized by?

<p>Nausea, vomiting, and abdominal pain after long-term, heavy cannabis use (C)</p>
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Which gastrointestinal issue is NOT mentioned in relation to cannabis use?

<p>Gastroesophageal reflux disease (B)</p>
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What is a common risk associated with long-term cannabis use?

<p>Increased likelihood of developing head, neck, or throat cancer (C)</p>
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How is hashish primarily produced?

<p>By extracting and compressing THC-rich resin from the plant (A)</p>
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What is the primary component extracted in hashish oil production?

<p>Cannabinoids (D)</p>
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Which of the following statements about hashish is true?

<p>Hashish is made from the THC-rich resin of the cannabis plant (B)</p>
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Which region is NOT commonly associated with the production of hashish?

<p>Brazil (D)</p>
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What is the equivalent potency of a drop of hashish oil compared to marijuana?

<p>Equal to a single marijuana joint (B)</p>
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What compound is primarily responsible for the intoxicating effects of cannabis?

<p>Tetrahydrocannabinol (THC) (A)</p>
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Which cannabinoid is commonly marketed for its potential health benefits and is non-intoxicating?

<p>Cannabidiol (CBD) (C)</p>
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Which of the following statements about Delta-8 THC is true?

<p>High consumption can lead to medical emergencies. (C)</p>
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What is a significant use of cannabis sativa L plants that contain minimal amounts of delta-9 THC?

<p>Manufacturing textile fiber (B)</p>
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What side effect is NOT commonly associated with Cannabidiol (CBD)?

<p>Increased appetite (C)</p>
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What form does Marinol® take, and what type of substance is it classified as?

<p>Pill form; Schedule III controlled substance (D)</p>
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Why is hemp primarily used in various industries?

<p>For its non-intoxicating cannabinoid properties (B)</p>
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What is the main distinction between Delta-8 THC and CBD?

<p>Delta-8 THC has psychoactive properties, while CBD does not. (C)</p>
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Which of the following is NOT a short-term effect of cannabis use?

<p>Chronic bronchitis (C)</p>
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What psychological effect is more likely to occur with high doses of cannabis?

<p>Panic (A)</p>
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Which of the following cardiovascular effects is linked to long-term cannabis use?

<p>Increased risk of stroke (B)</p>
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What is a common physical side effect of cannabis use?

<p>Dry mouth (D)</p>
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Which short-term effect of cannabis involves altered time perception?

<p>Delayed response (A)</p>
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Which of the following effects is associated with the use of cannabis for managing nausea or vomiting?

<p>Increased appetite (D)</p>
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Which factor contributes to the increased risk of psychological effects from cannabis?

<p>High THC levels in the product (C)</p>
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Which respiratory issue is associated with long-term cannabis smoking?

<p>Lung hyperinflation (B)</p>
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What is the main psychoactive ingredient found in cannabis?

<p>Delta-9 tetrahydrocannabinol (THC) (B)</p>
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Which statement correctly distinguishes between hashish and marijuana?

<p>Hashish is made from the resin of the cannabis plant. (D)</p>
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What is the typical THC concentration in hashish?

<p>20-60% (C)</p>
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Which term does NOT typically refer to a product derived from the cannabis plant?

<p>Cocoa (A)</p>
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Which part of the cannabis plant does marijuana primarily come from?

<p>Dried buds and leaves (C)</p>
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What is the main purpose of trichomes on the cannabis plant?

<p>To repel pests and provide sunlight protection. (A)</p>
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Which of the following is a common name for high-quality marijuana?

<p>Sinsemilla (C)</p>
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Which of the following statements about cannabis products is true?

<p>Hashish is generally more potent than marijuana. (C)</p>
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What is one of the primary effects of marijuana use on cognitive abilities?

<p>Difficulty with processing information (C)</p>
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Which cannabinoid receptor is primarily associated with the cognitive effects of THC?

<p>CB1 (A)</p>
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What negative effect might occur after using marijuana, according to the information provided?

<p>Difficulty learning new skills (B)</p>
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What role does CBD play at the CB1 receptor?

<p>Negative allosteric modulator preventing THC binding (B)</p>
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Which area of the brain is associated with the cognitive effects of THC due to the presence of CB1 receptors?

<p>Hippocampus and cortex (A)</p>
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What are synthetic cannabinoids primarily known for?

<p>Potentially life-threatening health effects (C)</p>
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What is a common effect on sensory perception caused by marijuana use?

<p>Poor sensory and time perception (C)</p>
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Which function is NOT associated with the impact of THC on the brain?

<p>Memory recall improvement (A)</p>
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Flashcards

THC

Tetrahydrocannabinol, the main psychoactive compound found in cannabis, responsible for the 'high'.

What is Cannabidiol (CBD)?

Cannabidiol (CBD) is a compound found in cannabis that is used for medical reasons, including treating loss of appetite in AIDS patients and nausea and vomiting caused by cancer chemotherapy.

What is Marinol?

Marinol is a medication containing THC, the psychoactive compound in cannabis, used to treat nausea, vomiting, and loss of appetite.

CBD

Cannabidiol, a non-psychoactive compound in cannabis, marketed for various health benefits.

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How can cannabis be ingested?

Cannabis can be ingested through various methods, including smoking, vaporization, and oral consumption (oils, capsules, edibles, tinctures, lozenges).

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Delta-8 THC

A natural compound found in the cannabis plant, known for its intoxicating effects.

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What are topical and suppository forms of cannabis?

Topical and suppository forms of cannabis are used for medication purposes, allowing direct application to target areas.

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Marinol

A prescription drug containing CBD, used to treat symptoms like nausea and loss of appetite.

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What are vaporizers (like G-Pen) used for?

Vaporizers, like the G-Pen, are devices used to vaporize cannabis, producing a discreet way to consume it that doesn't involve smoke or odor.

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Cannabis sativa L

The plant species that produces cannabis, containing varying amounts of THC and CBD.

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Hemp

A variety of cannabis with very low THC levels, used for fiber and seed oil production.

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Cannabinoids

Chemicals found in cannabis, including THC and CBD.

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CBD Products

Products marketed for various uses, often containing CBD.

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What is Cannabis?

Cannabis, also known as marijuana, is the dried leaves, flowers, stems, and seeds of the Cannabis sativa L plant.

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What is THC?

Delta-9 tetrahydrocannabinol (THC) is the major psychoactive ingredient in cannabis, contributing to its intoxicating effects.

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What are the effects of Cannabis?

Cannabis has intoxicating effects, meaning it can temporarily alter a person's mood, thoughts, and perceptions.

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What is Hashish?

Hashish is a concentrated form of cannabis made from the resin exuded by the leaves of the cannabis plant. It's more potent than weed.

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Difference between Cannabis, Weed, and Hash?

Weed, marijuana, and hash are terms that describe different products made from the cannabis plant. They are often used interchangeably.

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What are Trichomes?

Trichomes are hair-like structures on the cannabis plant. They contain cannabinoids such as THC.

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How is Hashish made?

Hashish is made by compressing trichomes from the cannabis plant.

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What does the Opium Act use?

The Opium Act uses the terms 'hemp' and 'cannabis' interchangeably.

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Short Term Effects of Cannabis

Cannabis use can lead to feeling happy, relaxed, and experiencing altered perception of time, impaired thinking, memory, and movement, also causing irritability and restlessness.

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Anxiety and Hallucinations from Cannabis

Using large amounts of cannabis, especially high THC products, can lead to feelings of anxiety, fear, distrust, panic, and hallucinations.

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Physical Side Effects of Cannabis

Cannabis use can cause increased appetite, which can be beneficial for managing nausea and vomiting in chemotherapy patients. However, it can also lead to increased heart rate and respiratory issues.

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Specific Short-Term Effects of Cannabis

Cannabis use can cause red eyes, dry mouth, altered skin sensation, increased appetite, feelings of pleasure and bliss, paranoia, impaired motor coordination, altered perception, muscle relaxation, and increased heart rate.

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Memory Loss from Cannabis

Cannabis can cause temporary memory loss, this effect can be more noticeable when using larger amounts, long term use can also contribute to memory issues.

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Long-Term Lung Health Risks from Cannabis

Long-term cannabis smoking can lead to various respiratory problems, including inflammation, increased airway resistance, lung hyperinflation, and chronic bronchitis.

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Cardiovascular Risks of Long-Term Cannabis Use

Long-term cannabis use is associated with an increased risk of stroke, heart attack, and arrhythmias, however, more research is needed to understand these connections.

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Overall Effects of Cannabis

Cannabis use can have a range of short-term and long-term effects impacting both mental and physical health. It's important to understand these effects and use cannabis responsibly.

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Cannabinoid Hyperemesis Syndrome (CHS)

A condition caused by long-term, heavy cannabis use that results in nausea, vomiting, and abdominal pain.

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Cannabis Drugs

A group of drugs derived from the cannabis plant, known for their psychoactive effects. They include marijuana, hashish, and hashish oil.

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Hashish

A concentrated form of cannabis produced from the resinous material of the plant. It is stronger than marijuana and comes in forms like balls, cakes, or sheets.

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Hashish Oil

An extract of cannabis produced by using a solvent to extract cannabinoids. Its color and odor vary based on the chosen solvent.

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Acid Reflux

A condition where stomach acid flows back into the esophagus.

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Pancreatitis

An inflammation of the pancreas.

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Peptic Ulcer Disease

A sore in the lining of the stomach or duodenum.

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Increased Cancer Risk from Tobacco Use

A condition where smoking or chewing tobacco increases the risk of developing cancer in the head, neck, or throat.

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Effects of Marijuana on Cognitive Function

Effects of marijuana use can include memory problems, difficulty processing information, impaired sensory perception, poor time perception, and issues with concentration and coordination.

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Long-Term Impairment from Marijuana

Long-term marijuana use can lead to challenges with complex tasks, learning new skills, maintaining alertness and attention, recalling information, and making decisions.

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Cannabinoid Receptors (CB1 and CB2)

The CB1 receptor is located throughout the nervous system, while the CB2 receptor is mainly found in the immune system. THC, the psychoactive compound in marijuana, activates the CB1 receptor.

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CB1 Receptor and Its Effects in the Brain

Activation of the CB1 receptor in the hippocampus and cortex may be responsible for the perceptual and cognitive effects of marijuana. Activation in the basal ganglia and cerebellum contributes to sedation and movement effects.

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CB1 Receptor and Pain Relief

CB1 receptors found in the spinal cord and brainstem might be involved in the pain-relieving (analgesic) effects of marijuana.

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CBD and Its Effect on CB1 Receptor

CBD, another compound found in marijuana, acts as a negative allosteric modulator of the CB1 receptor. This means it prevents THC from binding to the receptor effectively.

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Synthetic Cannabinoids: Spice or K2

Synthetic cannabinoids are lab-made substances similar to compounds found in marijuana. These substances can have much higher THC levels and are associated with severe health risks.

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Health Risks of Synthetic Cannabinoids

Synthetic cannabinoid use is linked to several serious and potentially life-threatening health issues. These include severe psychological effects, cardiovascular problems, and respiratory distress.

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Study Notes

Marijuana (Cannabis)

  • Marijuana refers to dried leaves, flowers, stems, and seeds of the Cannabis sativa L plant.
  • It contains at least 125 cannabinoids, including delta-9 tetrahydrocannabinol (THC), the primary psychoactive component.
  • THC has intoxicating effects, altering mood, thoughts, and perceptions temporarily.
  • Hashish is resin from cannabis leaves, protecting them from the sun's rays.
  • Cannabis, weed, hemp, and hash are often used interchangeably, though technically different forms of the plant.

Variations of Marijuana

  • Weed/marijuana is made from dried buds and leaves.
  • Hashish/hash is made from resin from buds, pressed into a sticky brown substance. Hashish typically has a higher THC concentration (20-60%) compared to other forms (25-30%).

Marijuana Basics: Common Forms

  • Images of different forms of marijuana are presented.

Trichomes and Hashish

  • Trichomes are hair-like structures on the plant.
  • Trichomes are the main component of hashish.

Different Names for Marijuana

  • Various terms for marijuana are presented (e.g., Mary Jane, Dank Marijuana, Kief, 420, Sinsemilla, Brocc Oli Haze, Hashish, Reefer, Mota, Ganja, Kush, Pot, Blunt).
  • These terms are used in different contexts and often interchangeably.

Marijuana Components

  • Marijuana plants contain approximately 100 cannabinoids, including examples like THC, THCV, delta-8-tetrahydrocannabinol (delta-8 THC), cannabigerol (CBG), cannabinol (CBN), cannabichromene (CBC), and cannabidiol (CBD).
  • Different cannabinoids have different concentrations within the plant.

The Science of THC and CBD

  • THC (tetrahydrocannabinol) is the major psychoactive component.
  • CBD (cannabidiol) is a non-intoxicating cannabinoid.

CBD

  • CBD is found in cannabis plants and is marketed as an ingredient in various consumer products (e.g., supplements, foods, oils, lotions).
  • CBD is not intoxicating in the same way as THC.
  • CBD can have side effects, including drowsiness, decreased appetite, vomiting, and diarrhea.

Delta-8 THC

  • Delta-8 THC is a cannabinoid potentially found in cannabis plants.
  • Delta-8 THC products are not FDA-approved for safe use.
  • Large amounts of delta-8 THC may cause medical emergencies, including breathing problems.

Marinol®

  • Marinol® is a Schedule III controlled substance containing cannabinoid CBD.
  • It is available in pill form.
  • Prescribed to treat loss of appetite and nausea/vomiting (often from chemotherapy or AIDS).

How Marijuana is Taken

  • Smoking: Direct inhalation of smoked plant material.
  • Vaporization: Inhalation of vaporized liquid extract.
  • Oral: Ingestion in various formats (oils, capsules, edibles, tinctures, lozenges).
  • Topical and suppositories: Used for topical/medicinal use.
  • Vaporizers, such as the G-Pen, allow for intake without smoke.
  • These are particularly popular with teenagers.

Marijuana, the Brain, and Impairment

  • THC affects cannabinoid receptors in the brain.
  • These receptors influence pleasure, memory, thinking, sensory perception, movement, and concentration.
  • A "high" is created when these brain areas are overstimulated.
  • Long-term effects include complex task difficulty, new skill learning challenges, problems with alertness, attention, and information recall.

THC Mechanism of Action (MOA)

  • There are two types of cannabinoid receptors in the body (CB1 and CB2.)
  • CB1 is found in the brain.
  • THC activates CB1 receptors (it's an agonist.)
  • CB1 receptors are active in areas of the brain that influence perception, cognition, and motor function.

CBD Mechanism of Action (MOA)

  • CBD works on the CB1 receptor as a negative allosteric modulator.
  • This prevents THC from binding effectively, potentially modulating THC's effects.

Synthetic Cannabinoids

  • Synthetic cannabinoids are lab-created chemicals that mimic natural cannabinoids.
  • They can be much more powerful than natural cannabinoids.
  • Often sold under names like Spice or K2.
  • Use of synthetic cannabinoids can have severe, potentially life-threatening health effects.

Short-Term Effects

  • Intoxication: Temporary state of altered mood/perception.
  • Anxiety, Fear, Distrust, Panic, or Hallucinations: Often more prevalent with stronger products or in users inexperienced with cannabis.
  • Physical Side Effects: Can include increased appetite, altered perception, muscle relaxation, increased heart rate, and possible nausea/vomiting.
    • Side effects vary considerably by dosage and individual tolerance

Long-Term Health Risks

  • Lung health: Long-term cannabis smoking can negatively impact respiratory health.
  • Cardiovascular issues: Increased risk of stroke, heart attacks, and irregular heartbeats (arrhythmias).
  • Gastrointestinal Issues: Conditions include cannabinoid hyperemesis syndrome, pain, nausea, and vomiting.
  • Cancer: Potential increased risk of certain cancers of the head and neck region.

Similar Substances

  • Hashish/hashish oil: Highly concentrated THC extracts from cannabis.
  • Different preparation methods result in various forms like balls, cakes, or cookie sheets.
  • Hash oil is prepared by extracting THC with a solvent (the color and odor will vary).

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