Male Genital System Pathology: Prostate (BPH)
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Questions and Answers

What is the most common clinical presentation of advanced localized prostate cancer?

  • Elevated alkaline phosphatase
  • Lower back pain (correct)
  • Benign gland enlargement
  • Urinary tract obstruction

    • What is the primary method for detecting the tumor in the prostate?

  • Digital rectal exam (induration) (correct)
  • Serum PSA level
  • Elevated alkaline phosphatase
  • Transrectal U/S and biopsy

    • Which glands infiltrate between the benign glands in prostate cancer?

  • Enlarged nuclei
  • Basal cells
  • Crowded small circular glands (correct)
  • Prominent large nucleoli

    • What is the most common site of metastases in prostate cancer?

    <p>Obturator and pelvic lymph nodes</p> Signup and view all the answers

    How is metastatic prostate cancer primarily treated?

    <p>Orchiectomy, estrogens, or LHRH agonists and anti-androgens</p> Signup and view all the answers

    What is the primary pathology described in the passage?

    <p>Benign prostatic hyperplasia</p> Signup and view all the answers

    What is the main factor responsible for the synthesis of Dihydrotestosterone (DHT) in the prostate?

    <p>Circulating testosterone</p> Signup and view all the answers

    Which zone of the prostate is primarily affected by Benign prostatic hyperplasia (BPH)?

    <p>Transition zone</p> Signup and view all the answers

    What is the most common clinical presentation of Benign prostatic hyperplasia (BPH)?

    <p>Urinary retention and hesitancy</p> Signup and view all the answers

    How is adenocarcinoma graded in the prostate?

    <p>Gleason system</p> Signup and view all the answers

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