31 Questions
What is the main function of lymph nodes in the lymphatic system?
To filter lymph and facilitate the response of lymphocytes to antigens
What is the composition of the stroma in a lymph node?
Reticular fibres, reticular cells, capsule, and trabeculae
What structures separate the parenchyma from the capsule and trabeculae in a lymph node?
Lymphatic sinuses
What is the shape of lymph nodes?
Ovoid or kidney-shaped
What type of vessels enter the lymph node through the capsule at various intervals on its convex surface?
Afferent lymphatic vessels
What do the afferent lymphatic vessels flow into upon entering the lymph node?
Subcapsular sinus
What prevents the lymph from going back in the afferent and efferent lymphatic vessels?
Valves
What is the supportive framework of the lymphatic sinuses made up of?
Reticular cells and fibres
Where are high endothelial venules (HEV) located within the lymph node?
Cortical parenchyma
What do high endothelial venules (HEV) lack?
Muscular layer
Which vessels are the port of entry into the lymph node for lymphocytes carried by the blood?
Capillaries
What is the structure of the pig lymph nodes like compared to other species?
They have several nodular units with central medullary tissue and wide medullary sinuses.
What kind of cells are observed in the lumen of the medullary sinuses?
T cells, B cells, and macrophages
What is located in the outer region of the cortex of a lymph node?
Lymphoid follicles and interfollicular areas
What elements facilitate the interaction between antigens with macrophages and dendritic cells?
Macrophages and dendritic cells
What do the lymphatic sinuses allow filtering into the parenchyma?
Substances in solution, particles in suspension, and cells
What is the specific function of the lymph nodes' microenvironment?
Filtering antigens from lymph
What is the composition of the lymph node stroma primarily made up of?
Type III collagen and reticular cells
What separates the parenchyma from the capsule and trabeculae in a lymph node?
Lymphatic sinuses
What is the shape of the lymph nodes?
Oval or kidney-shaped
What is the shape of the lymphatic sinuses in the medulla of a lymph node?
Irregular
Where do the medullary sinuses drain the efferent lymphatic vessels in pig lymph nodes?
Spaces between the nodular units
What is the composition of the cords in the medulla of a lymph node?
T cells, B cells, plasma cells, and macrophages
What is the structure of the medullary tissue distribution in pig lymph nodes?
Around the periphery of the nodular units and around the efferent hilum
Where are high endothelial venules (HEV) located within the lymph node?
In the interfollicular area and paracortex
What is the main function of high endothelial venules (HEV) in a lymph node?
To allow entry of lymphocytes carried by the blood
What prevents backflow of lymph in both afferent and efferent lymphatic vessels?
Valves
What do dendritic cells and macrophages located in the wall of medullary sinuses facilitate?
Interaction between antigens and immune cells
What is located in the outer region of the cortex of a lymph node?
Lymphoid follicles and interfollicular areas
What type of vessels carry lymphocytes into the parenchyma of a lymph node from primary lymphoid organs or blood recirculation?
Postcapillary venules
What is the supportive framework of the lymphatic sinuses made up of?
Reticular cells and fibres
Learn about the structure and function of lymph nodes, which are secondary lymphoid organs distributed along the lymphatic vessels. Understand their parenchyma and connective tissue stroma, as well as the entry and exit points for arteries, veins, and lymphatic vessels.
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