Lymphadenopathy Differential Diagnosis Quiz

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29 Questions

Which of the following is a potential cause of lymphadenopathy in the axilla?

Silicone breast implants

What is a common malignancy that can metastasize to the axilla?

Breast cancer

In the context of lymphadenopathy, absence of an infectious source or traumatic lesions can be suggestive of which malignant condition?

Hodgkin lymphoma

What is a potential differential diagnosis for lymphadenopathy associated with submandibular nodes?

Mycobacterial/fungal infections

Which type of cancer is NOT mentioned as a malignancy that can metastasize to the axilla?

Thyroid cancer

Which of the following lymph node qualities is associated with reactive lymphadenopathy from a viral infection?

Shotty lymphadenopathy

What characteristic is suggestive of malignancy in a lymph node?

Painless and hard

In head and neck lymphadenopathy, which area is commonly associated with infection?

Submandibular

What type of lymphadenopathy is described by having multiple small lymph nodes that feel like 'buck shots' under the skin?

Shotty

Which characteristic of lymphadenopathy is generally unable to reliably predict malignancy?

Mobile and fluctuant

What can painful or tender lymphadenopathy represent besides possible inflammation caused by infection?

Hemorrhage into a node

Which type of malignancy is NOT typically found in the inguinal region?

Lymphomas

What is a common etiology for inguinal lymphadenopathy?

Syphilis

What structures do the anterior cervical nodes drain?

Larynx, tongue, oropharynx, anterior neck

What factor increases the likelihood of inguinal lymphadenopathy in healthy adults?

Walking outdoors barefoot, especially in tropical regions

Which structure drains into the inguinal lymphatics?

Anal canal

Which condition is highly suspicious for when presenting with infraclavicular nodes?

Non-Hodgkin lymphoma

What structures do the axillary nodes drain?

Breast, upper extremity, thoracic wall

What is a potential cause of inguinal lymphadenopathy unrelated to infections?

Skin neoplasms

What is the differential diagnosis for epitrochlear lymphadenopathy?

Skin infections, lymphomas, and skin malignancies

Which sexually transmitted infection is NOT commonly associated with inguinal lymphadenopathy?

Chlamydia

What does epitrochlear lymphadenopathy greater than 5 mm usually suggest?

Lymphoma or melanoma

What can cause axillary lymphadenopathy due to an inflammatory reaction to silicone particles?

Implant leakage

What is the significance of lymphadenopathy lasting less than two weeks or greater than 12 months without change in size in adults and children?

Low likelihood of being neoplastic

Which age group is more likely to have palpable lymph nodes at any one time?

Children

What should be reviewed in terms of exposures when investigating lymphadenopathy?

Chronic medication use

What type of lymphoma might show exceptions to the typical duration guidelines for neoplastic lymphadenopathy?

Low-grade Hodgkin lymphoma

In which age group is most lymphadenopathy benign or infectious in etiology?

Children

What is the significance of associated systemic symptoms in low-grade Hodgkin lymphomas and indolent nonHodgkin lymphoma?

They might not exhibit associated systemic symptoms

Test your knowledge on differentiating causes of lymphadenopathy in the axilla, including infectious diseases and malignant etiologies such as lymphoma and metastatic cancers. Explore scenarios involving cat-scratch disease, tularemia, sporotrichosis, and more.

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