Questions and Answers
What is the trade name for Lisinopril?
What class of medication does Lisinopril belong to?
ACE inhibitors, antihypertensives
What is the FDA category for Lisinopril?
D
What are the therapeutic uses of Lisinopril?
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What is the mechanism of action of Lisinopril?
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The starting dose of Lisinopril is ______ mg daily.
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Common side effects of Lisinopril include ______.
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Which of the following are contraindications for Lisinopril?
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What should be monitored in patients taking Lisinopril?
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What patient teaching is advised for those on Lisinopril?
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Study Notes
Lisinopril Overview
- Generic name: Lisinopril; trade names include Prinivil and Zestril.
- Belongs to the ACE inhibitors class, categorized as antihypertensives.
FDA Category
- Classified as Category D, indicating potential risks during pregnancy.
Therapeutic Uses
- Primarily used to reduce blood pressure.
- Improves hemodynamics in patients with heart failure.
- Effective in treating heart failure post-myocardial infarction (MI).
Mechanism of Action
- Inhibits the angiotensin-converting enzyme (ACE), crucial in regulating blood pressure.
Dosage Information
- Initial dosage ranges from 0.5 to 10 mg daily.
- Maintenance dose typically falls between 20 to 40 mg, administered once or twice daily by oral route.
Common Side Effects
- First-dose hypotension can occur.
- Notable side effects include cough, hyperkalemia (elevated potassium), dysgeusia (altered taste), and rash.
Contraindications
- Should not be used during the second and third trimesters of pregnancy.
- Contraindicated in patients with bilateral artery stenosis, renal impairment, and those on diuretics or other antihypertensive agents.
- Care needed with medications that can increase potassium levels and NSAIDs.
Nursing Considerations
- Monitor patients with renal impairment carefully.
- Regularly check blood pressure and ensure hydration is maintained.
Pre-Administration Assessment
- Assess baseline blood pressure before administration.
- Obtain white blood cell (WBC) count and differential for safety monitoring.
Laboratory Tests
- Monitor WBC count alongside blood pressure measurements two hours after the initial dose and periodically thereafter.
Patient Teaching
- Advise on contraception due to pregnancy risks.
- Instruct patients to report any signs of infection.
- Recommend limiting the use of NSAIDs to avoid complications.
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Description
This quiz covers essential information about Lisinopril, including its classification as an ACE inhibitor, therapeutic uses, mechanism of action, and dosage information. It also addresses potential side effects and contraindications, particularly regarding its use during pregnancy. Test your knowledge of this important antihypertensive medication!
