Podcast
Questions and Answers
Which type of lipids contain phosphate in addition to fatty acids and alcohol?
Which type of lipids contain phosphate in addition to fatty acids and alcohol?
- Derived lipids
- Glycolipids
- Compound lipids (correct)
- Waxes
Where are fatty acids mainly found in natural fats?
Where are fatty acids mainly found in natural fats?
- In waxes
- As unesterified form (correct)
- In the plasma
- In compound lipids
What is the term for fatty acids containing no double bonds?
What is the term for fatty acids containing no double bonds?
- Phospholipids
- Saturated (correct)
- Unsaturated
- Monocarboxylic
What does the term 'ω9' indicate in relation to a fatty acid chain?
What does the term 'ω9' indicate in relation to a fatty acid chain?
Which carbon is referred to as the omega carbon in fatty acids?
Which carbon is referred to as the omega carbon in fatty acids?
In which lipids can derived lipids be found in association with nature?
In which lipids can derived lipids be found in association with nature?
What is phosphatidylglycerol formed from?
What is phosphatidylglycerol formed from?
How many glycerol molecules are present in cardiolipins?
How many glycerol molecules are present in cardiolipins?
What makes plasmalogens different from other phospholipids?
What makes plasmalogens different from other phospholipids?
Where are cardiolipins found in the human body?
Where are cardiolipins found in the human body?
How many phosphates are present in diphosphatidylglycerol?
How many phosphates are present in diphosphatidylglycerol?
What characterizes the R group in plasmalogens?
What characterizes the R group in plasmalogens?
What is the precursor of the ω6 family of polyenoic acids?
What is the precursor of the ω6 family of polyenoic acids?
Which acids are present in nuts, olives, and various oils such as sunflower, cottonseed, and corn oil?
Which acids are present in nuts, olives, and various oils such as sunflower, cottonseed, and corn oil?
What physical properties dictate that fatty acids containing up to six carbons are completely soluble in water?
What physical properties dictate that fatty acids containing up to six carbons are completely soluble in water?
Which fatty acids are considered essential and not synthesized in our body?
Which fatty acids are considered essential and not synthesized in our body?
Which fatty acids are classified as non-essential and are formed in our body mainly from carbohydrates?
Which fatty acids are classified as non-essential and are formed in our body mainly from carbohydrates?
What beneficial health effects do ω3 PUFAs provide?
What beneficial health effects do ω3 PUFAs provide?
Where are phytosterols primarily found?
Where are phytosterols primarily found?
Which organ can synthesize its own cholesterol?
Which organ can synthesize its own cholesterol?
What form does free cholesterol take?
What form does free cholesterol take?
Where is cholesterol found in the highest concentrations?
Where is cholesterol found in the highest concentrations?
What can cholesterol be converted into in the liver?
What can cholesterol be converted into in the liver?
What is cholesterol's main role in cell membranes?
What is cholesterol's main role in cell membranes?
What is the structure of gangliosides composed of?
What is the structure of gangliosides composed of?
Where are glycolipids mainly found in the body according to the text?
Where are glycolipids mainly found in the body according to the text?
What is the main function of gangliosides in cell membranes?
What is the main function of gangliosides in cell membranes?
Which lipids are produced by the hydrolysis of either simple or conjugated lipids according to the text?
Which lipids are produced by the hydrolysis of either simple or conjugated lipids according to the text?
How many carbon atoms are present in the steroid nucleus as described in the text?
How many carbon atoms are present in the steroid nucleus as described in the text?
What is the classification of steroids discussed in the text?
What is the classification of steroids discussed in the text?
Flashcards are hidden until you start studying
Study Notes
Biomedical Intake
- Decreased plasma cholesterol and polyenoic acids
- ω6 PUFAs (e.g., linoleic acid) and ω3 PUFAs (e.g., α-linolenic acid) are present in nuts, oils, flaxseed, canola, and fish oil
- Intake of ω6 PUFAs may lead to decreased plasma cholesterol
- Intake of ω3 PUFAs may reduce the incidence of cardiovascular disease by:
- Lowering blood pressure
- Lowering plasma triacylglycerol levels
- Decreasing the tendency to thrombosis
Nutritional Classification of Fatty Acids
- Essential Fatty Acids (EFAs):
- Not synthesized in the body, must be taken in through diet
- Include α-linolenic and linoleic acids
- Deficiency produces: dermatitis in infants, fatty liver, growth retardation, defective sperms, brain, and retina
- Non-Essential Fatty Acids:
- Formed in the body from carbohydrates
- Not essential to take in through diet
Physical Properties of Fatty Acids
- Solubility in water:
- Fatty acids with up to six carbons are completely soluble in water
- Waxes: esters of fatty acids with higher molecular weight monohydric alcohols
- Compound lipids:
- Phospholipids: contain phosphate in addition to fatty acids and alcohol
- Glycolipids (glycosphingolipids): contain a fatty acid, sphingosine, and carbohydrate
Fatty Acids
- Occur mainly as esters in natural fats and oils
- Fatty acids that occur in natural fats are usually monocarboxylic acids containing an even number of carbon atoms
- Chain may be saturated (no double bonds) or unsaturated (one or more double bonds)
Nomenclature of Fatty Acids
- Carbon atoms are numbered from the carboxyl carbon (carbon No. 1)
- The carbon atoms adjacent to the carboxyl carbon are numbered as 2, 3…etc and are also known as α, β…etc, carbons respectively
- The terminal methyl group is known as the ω carbon, used to indicate the site of a double bond
Phosphatidylglycerol
- Formed from phosphatidic acid and glycerol
Cardiolipins (Diphosphatidylglycerol)
- Formed from two molecules of phosphatidic acid connected by a molecule of glycerol
- Contain 4 FAs, 3 glycerol, and 2 phosphates
- Important component of inner mitochondrial membrane
Plasmalogens
- Type of ether phospholipid
- Characterized by the presence of an enol form of fatty alcohol in ether linkage at position-1, a fatty acid at position-2, and an R-group at position-3
- Found in numerous human tissues (e.g., nervous and cardiovascular system)
Sterols
- Include zoosterols (animals and humans), phytosterols (higher plants), and mycosterols (lower plants, yeast, and fungi)
- Cholesterol:
- Exogenous (dietary) sources: eggyolk, red meat, liver, kidney, butter, and brain
- Endogenous: synthesized by the liver and intestine
- Present in all tissues, but higher concentrations in nervous tissue, liver, adrenals, gonads, skin, and adipose tissue
- Plasma level: 120-200 mg/dL (30% free, 70% esterified)
- Importance and derivatives of cholesterol:
- Converted into bile acids and bile salts in the liver
- Precursor of all steroid hormones
- Can be oxidized into 7-dehydrocholesterol, then converted into vitamin D3 under UV rays
- Important constituent of cell membranes
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
