Questions and Answers
What is the therapeutic class of Leuprolide (Eligard, Lupron)?
What is the pharmacologic class of Leuprolide (Eligard, Lupron)?
What is the action of Leuprolide (Eligard, Lupron)?
Stimulates and inhibits the release of FSH and luteinizing hormone, which suppresses testosterone and estrogen levels.
Which of the following are potential side effects of Leuprolide (Eligard, Lupron)? (Select all that apply)
Signup and view all the answers
What are the indications for Leuprolide (Eligard, Lupron)? (Select all that apply)
Signup and view all the answers
Leuprolide (Eligard, Lupron) has significant adverse drug interactions.
Signup and view all the answers
What nursing implications should be considered before starting Leuprolide (Eligard, Lupron)?
Signup and view all the answers
What teaching should be provided to patients receiving Leuprolide (Eligard, Lupron)? (Select all that apply)
Signup and view all the answers
What routes of administration are available for Leuprolide (Eligard, Lupron)?
Signup and view all the answers
Study Notes
Leuprolide Overview
- Leuprolide is an antineoplastic medication used primarily in hormone-related conditions.
- Trade names include Eligard and Lupron.
Therapeutic Class
- Classified as an antineoplastic, indicating its use in cancer treatment.
Pharmacologic Class
- Functions as a Gonadotropin Releasing Hormone (GnRH) analog, affecting hormone secretion.
Mechanism of Action
- Initially stimulates and subsequently inhibits the release of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH).
- Results in decreased levels of testosterone and estrogen.
Side Effects
- Potentially serious effects include:
- Arrhythmias
- Bone loss
- Myocardial Infarction (MI)
- Pulmonary Fibrosis
- Other side effects may encompass:
- Gynecomastia
- Androgen-like effects
- Nausea and vomiting
- Amenorrhea
- Hot flashes
Indications
- Approved for treating:
- Advanced prostate cancer
- Endometriosis
- Central precocious puberty
- Anemia related to uterine fibroids
- Ovarian suppression in premenopausal breast cancer patients
Adverse Drug Interactions
- No significant drug interactions reported, making it a safer option regarding polypharmacy.
Nursing Implications
- Ensure correction of any electrolyte abnormalities prior to initiation of therapy.
- Monitor for initial worsening of symptoms related to prostate cancer or precocious puberty.
- Post-treatment evaluation of patient response is crucial, utilizing the GnRH stimulation test and monitoring corticosteroid levels.
Patient Teaching
- Educate patients on proper injection techniques for administration (IM and SubQ).
- Inform patients that symptoms may exacerbate initially after starting treatment.
- Recommend nonhormonal birth control for female patients.
- Emphasize correct storage: room temperature after opening, refrigeration before opening, avoiding heat and light exposure.
Routes of Administration
- Administered via Intramuscular (IM) or Subcutaneous (SubQ) injections.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz contains essential flashcards about Leuprolide, also known as Eligard or Lupron. It covers its therapeutic and pharmacologic classifications, as well as its mechanism of action. Ideal for students and professionals in the medical field who want to enhance their understanding of this medication.
