Leukocyte and Lymphoid Disorders Objectives

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Questions and Answers

What is the normal range for the absolute neutrophil count (ANC)?

  • $>4000/μL$
  • $500-1000/μL$
  • $500-4000/μL$
  • $1000-4000/μL$ (correct)

Which of the following is NOT a characteristic of chronic myelogenous leukemia (CML)?

  • Occurs primarily in early adulthood (correct)
  • Accelerated phase with worsening constitutional symptoms
  • Neoplasm of the myeloid stem cell
  • Terminal blast crisis phase with blast count >100,000

Which of the following is a key feature of multiple myeloma?

  • Decreased production of platelets and lymphocytes
  • Malignant transformation of mature plasma cells (correct)
  • Overproduction of normal red blood cells
  • Uncontrolled proliferation of immature myeloid cells

Which of the following is a common clinical manifestation of neutropenia?

<p>Increased risk and severity of infections (C)</p> Signup and view all the answers

What is the primary cytogenetic abnormality associated with chronic myelogenous leukemia (CML)?

<p>Philadelphia chromosome (translocation of chromosomes 9 and 22) (A)</p> Signup and view all the answers

Which of the following is a common complication of multiple myeloma?

<p>Decreased bone density and lytic lesions (D)</p> Signup and view all the answers

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