Leucocytes Benign Disorders - Quantitative Changes and Terminology

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What is the normal reference range for total white blood cell count in adults?

4.5 - 11.0 x 10^9 /L

Define leucocytosis.

Raised TWBC due to elevation in any of the populations of white blood cells.

Explain the term leucopenia.

TWBC lower than the reference range for the age, affecting one or more lineages.

Differentiate between relative and absolute values in white blood cell counts.

Differential gives the percentage of each WBC, while absolute count gives the actual number of each WBC/mm3 of blood.

List the different types of granulocytes.

Neutrophils, Eosinophils, Basophils

What are the two main types of phagocytic cells in the immune system?

Monocytes, Macrophages

What is the definition of neutrophilia?

Increase in the number precursors of neutrophils and count >7.5 x 10^9 /L in adults

List three causes of neutrophilia.

Infection, inflammatory conditions, autoimmune disorders

What is neutropenia?

An absolute reduction in the number of circulating neutrophils

List three causes of eosinophilia.

Allergy, infection, malignancy

What is hypereosinophilic syndrome?

Peripheral blood eosinophil count >1.5 x 10^9 /L, persistence of counts for more than 6 months, end organ damage

Define granulocytosis.

Increase in the count of all or one of the granulocytic components (neutrophils, basophils, eosinophils)

Learn about the quantitative changes in leucocytes, including terminologies like cytosis, philia, and cytopenia. Explore the differences between relative and absolute values in total white blood cell count and differential blood count.

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