Laxatives Mechanism of Action Quiz
24 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the definition of constipation?

  • Having a bowel movement every day
  • Having a bowel movement exactly 3 times per week
  • Having a bowel movement at least 3 times per week
  • Having a bowel movement less than 3 times per week (correct)

Which of the following is NOT a cause of constipation as mentioned in the text?

  • Ignoring the urge to have a bowel movement
  • Decreased physical activity
  • Excessive physical activity (correct)
  • Diet low in fiber and inadequate fluid intake

Which of the following is considered a metabolic and endocrine disorder that can lead to constipation?

  • Irritable bowel syndrome (IBS)
  • Anal fissures
  • Hemorrhoids
  • Diabetes mellitus with neuropathy (correct)

What is the recommended first-line treatment for constipation according to the text?

<p>Non-pharmacological treatment including a diet rich in fibers (D)</p> Signup and view all the answers

Which of the following is NOT a class of drugs that can contribute to constipation?

<p>Antibiotics (B)</p> Signup and view all the answers

Which neurological condition can be associated with neurogenic constipation according to the text?

<p>Head trauma (D)</p> Signup and view all the answers

Which type of laxative works by retaining water in the gut and distending the large intestine?

<p>Bulk-forming agents (A)</p> Signup and view all the answers

What is a potential adverse effect of bulk-forming agents?

<p>Intestinal obstruction (A)</p> Signup and view all the answers

Which osmotic laxative may produce hypermagnesemia and hypernatremia in patients with renal failure?

<p>Mg sulfate &amp; Na salts (D)</p> Signup and view all the answers

What is the onset of action for osmotic laxatives like Polyethylene glycol?

<p>24-72 hours (C)</p> Signup and view all the answers

How do bulk-forming agents stimulate peristalsis?

<p>By retaining water in the gut and distending the large intestine (D)</p> Signup and view all the answers

Which laxative type works by their osmotic effect to activate stretch receptors and stimulate peristalsis?

<p>Osmotic laxatives (D)</p> Signup and view all the answers

Which of the following laxatives would be most appropriate for an infant or child?

<p>Polyethylene glycol (PEG) (A)</p> Signup and view all the answers

What is the laxative of choice for pregnant women?

<p>Bisacodyl (D)</p> Signup and view all the answers

Which drug is most suitable for long-term use as a laxative?

<p>Lactulose (B)</p> Signup and view all the answers

What is the drug of choice for Diabetic gastroparesis?

<p>Metoclopramide (C)</p> Signup and view all the answers

Which antihypertensive drug would be contraindicated in a patient with insulin-dependent diabetes, IBS, and HTN?

<p>Both A &amp; B (A)</p> Signup and view all the answers

When using lubricant laxatives, which of the following is NOT considered a lubricant laxative?

<p>Docusate (A)</p> Signup and view all the answers

Which laxative produces inflammation of the intestinal mucosa and inhibits Na+/K+ ATPase enzyme?

<p>Castor oil (B)</p> Signup and view all the answers

What is the mechanism of action for Lubiprostone and Linaclotide?

<p>Activating chloride channels (A)</p> Signup and view all the answers

Which laxative takes effect within 15—60 minutes after rectal administration?

<p>Docusate sodium (B)</p> Signup and view all the answers

What is the approved use for Lubiprostone (Amitiza)?

<p>Chronic idiopathic constipation and constipation-predominant IBS-C in adults (C)</p> Signup and view all the answers

What is the onset of action for stool softeners like Docusate sodium after oral administration?

<p>12-72 hours (B)</p> Signup and view all the answers

Which laxative acts by easing the passage of stool through activating chloride channels?

<p>Liquid paraffin (B)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser