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12 Questions

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Enzyme 2

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Questions and Answers

What is the location where lactate dehydrogenase operates?

Cytoplasm (correct)

Mitochondria

Golgi apparatus

Endoplasmic reticulum

What are the substrates for lactate dehydrogenase?

Pyruvate and Coenzyme NADH (correct)

Glucose and fructose

Glycogen and cellulose

Lactate and pyruvate

Which type of polypeptide subunit is found in cancer cells?

H (heart)

M (muscle)

J (joints)

K (submit) (correct)

What determines the relative percentage of aerobic and anaerobic pathways in cells?

Kinetic properties of each enzyme type Signup and view all the answers

In which type of cells is LDHk found?

Photoreceptors and cancer cells Signup and view all the answers

How does LDH influence corneal epithelial cells under low partial pressures of oxygen?

Promotes anaerobic metabolism Signup and view all the answers

In human cornea, which LDH isozyme has the highest percentage?

HM3 Signup and view all the answers

What is the influence of LDHk M4 on the retina due to its modification?

Increases oxygen sensitivity Signup and view all the answers

Which enzyme catalyzes the conversion of glucose to sorbitol and galactose to galactitol in certain disease conditions?

Aldose reductase Signup and view all the answers

What factor causes the activation of aldose reductase in the lens in diabetes?

High glucose or galactose concentration Signup and view all the answers

What is the primary impact of polyols like sorbitol and galactitol on lens fiber cells?

Induce cell swelling and bursting Signup and view all the answers

What type of sites are present on aldose reductase enzyme, particularly the inhibitory site?

Lipophilic Signup and view all the answers