Enzyme 2
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Enzyme 2

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@MarvellousDallas

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Questions and Answers

What is the location where lactate dehydrogenase operates?

  • Cytoplasm (correct)
  • Mitochondria
  • Golgi apparatus
  • Endoplasmic reticulum
  • What are the substrates for lactate dehydrogenase?

  • Pyruvate and Coenzyme NADH (correct)
  • Glucose and fructose
  • Glycogen and cellulose
  • Lactate and pyruvate
  • Which type of polypeptide subunit is found in cancer cells?

  • H (heart)
  • M (muscle)
  • J (joints)
  • K (submit) (correct)
  • What determines the relative percentage of aerobic and anaerobic pathways in cells?

    <p>Kinetic properties of each enzyme type</p> Signup and view all the answers

    In which type of cells is LDHk found?

    <p>Photoreceptors and cancer cells</p> Signup and view all the answers

    How does LDH influence corneal epithelial cells under low partial pressures of oxygen?

    <p>Promotes anaerobic metabolism</p> Signup and view all the answers

    In human cornea, which LDH isozyme has the highest percentage?

    <p>HM3</p> Signup and view all the answers

    What is the influence of LDHk M4 on the retina due to its modification?

    <p>Increases oxygen sensitivity</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of glucose to sorbitol and galactose to galactitol in certain disease conditions?

    <p>Aldose reductase</p> Signup and view all the answers

    What factor causes the activation of aldose reductase in the lens in diabetes?

    <p>High glucose or galactose concentration</p> Signup and view all the answers

    What is the primary impact of polyols like sorbitol and galactitol on lens fiber cells?

    <p>Induce cell swelling and bursting</p> Signup and view all the answers

    What type of sites are present on aldose reductase enzyme, particularly the inhibitory site?

    <p>Lipophilic</p> Signup and view all the answers

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