Dermatite de Contato
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Questions and Answers

What is one of the functions of the skin?

  • Reduce sensation
  • Enhance vulnerability to infections
  • Increase body temperature
  • Prevent insensible water loss (correct)
  • Which cells are part of the skin's immune system?

  • Erythrocytes
  • Langerhans cells and dermal DC (correct)
  • Platelets
  • Neutrophils
  • What is the role of Tregs in the skin immune system?

  • Produce antibodies
  • Regulate immune responses (correct)
  • Promote tissue damage
  • Cause inflammation
  • What is the main function of mast cells in the skin?

    <p>Release histamine and other inflammatory mediators</p> Signup and view all the answers

    What does the term 'Dermatitis' refer to?

    <p>Inflamed skin</p> Signup and view all the answers

    Which type of immune response is responsible for Allergic Contact Dermatitis?

    <p>Type IV immune response</p> Signup and view all the answers

    What is the most common manifestation of immunotoxicity in humans with Allergic Contact Dermatitis?

    <p>Erythema, itching, and vesicles</p> Signup and view all the answers

    What are some risk factors for developing contact allergy to at least one contact allergen?

    <p>Workplace exposure, age, sex, and genetic predispositions</p> Signup and view all the answers

    Which type of chemicals are most commonly responsible for causing Allergic Contact Dermatitis?

    <p>Low molecular weight chemicals</p> Signup and view all the answers

    What is the prevalence of Allergic Contact Dermatitis in 12–16 year olds?

    <p>$15-20%$</p> Signup and view all the answers

    What is the current view regarding the chances to develop hypersensitivity towards chemicals?

    <p>It depends on a balance between hapten-specific effector T cells and Treg lymphocytes</p> Signup and view all the answers

    What does LC stands for?

    <p>Langerhans Cells</p> Signup and view all the answers

    What is the cardinal feature of inflammation referring to increased blood flow?

    <p>Calor (heat)</p> Signup and view all the answers

    Which immune cells are responsible for T cell priming in the pathophysiology of Allergic Contact Dermatitis?

    <p>Dendritic cells</p> Signup and view all the answers

    What is the most common manifestation of immunotoxicity in humans with Allergic Contact Dermatitis?

    <p>Blistering and itching</p> Signup and view all the answers

    What is the primary risk factor for developing contact allergy to at least one contact allergen?

    <p>Genetic predispositions</p> Signup and view all the answers

    Which type of immune response is responsible for Allergic Contact Dermatitis?

    <p>Type IV immune response</p> Signup and view all the answers

    What is the cardinal feature of inflammation referring to irritation of nerves in inflamed tissues?

    <p>Dolor</p> Signup and view all the answers

    What is the role of dendritic cells in the pathophysiology of Allergic Contact Dermatitis?

    <p>Activation of keratinocytes</p> Signup and view all the answers

    Which cells are responsible for priming T cells in the pathophysiology of Allergic Contact Dermatitis?

    <p>Langerhans cells and dermal DC</p> Signup and view all the answers

    What are the primary constituents of innate immunity in the skin?

    <p>Langerhans cells and dermal DC</p> Signup and view all the answers

    Which type of immune response is primarily responsible for Allergic Contact Dermatitis?

    <p>Cell-mediated immune response</p> Signup and view all the answers

    What is the main function of mast cells in the context of skin immune system?

    <p>Release of inflammatory mediators</p> Signup and view all the answers

    What are the main functions of the skin, apart from acting as a physical barrier?

    <p>Preventing insensible water loss and controlling body temperature</p> Signup and view all the answers

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