Dermatite de Contato
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Questions and Answers

What is one of the functions of the skin?

  • Reduce sensation
  • Enhance vulnerability to infections
  • Increase body temperature
  • Prevent insensible water loss (correct)

Which cells are part of the skin's immune system?

  • Erythrocytes
  • Langerhans cells and dermal DC (correct)
  • Platelets
  • Neutrophils

What is the role of Tregs in the skin immune system?

  • Produce antibodies
  • Regulate immune responses (correct)
  • Promote tissue damage
  • Cause inflammation

What is the main function of mast cells in the skin?

<p>Release histamine and other inflammatory mediators (A)</p> Signup and view all the answers

What does the term 'Dermatitis' refer to?

<p>Inflamed skin (A)</p> Signup and view all the answers

Which type of immune response is responsible for Allergic Contact Dermatitis?

<p>Type IV immune response (C)</p> Signup and view all the answers

What is the most common manifestation of immunotoxicity in humans with Allergic Contact Dermatitis?

<p>Erythema, itching, and vesicles (D)</p> Signup and view all the answers

What are some risk factors for developing contact allergy to at least one contact allergen?

<p>Workplace exposure, age, sex, and genetic predispositions (A)</p> Signup and view all the answers

Which type of chemicals are most commonly responsible for causing Allergic Contact Dermatitis?

<p>Low molecular weight chemicals (C)</p> Signup and view all the answers

What is the prevalence of Allergic Contact Dermatitis in 12–16 year olds?

<p>$15-20%$ (A)</p> Signup and view all the answers

What is the current view regarding the chances to develop hypersensitivity towards chemicals?

<p>It depends on a balance between hapten-specific effector T cells and Treg lymphocytes (A)</p> Signup and view all the answers

What does LC stands for?

<p>Langerhans Cells (A)</p> Signup and view all the answers

What is the cardinal feature of inflammation referring to increased blood flow?

<p>Calor (heat) (A)</p> Signup and view all the answers

Which immune cells are responsible for T cell priming in the pathophysiology of Allergic Contact Dermatitis?

<p>Dendritic cells (D)</p> Signup and view all the answers

What is the most common manifestation of immunotoxicity in humans with Allergic Contact Dermatitis?

<p>Blistering and itching (C)</p> Signup and view all the answers

What is the primary risk factor for developing contact allergy to at least one contact allergen?

<p>Genetic predispositions (B)</p> Signup and view all the answers

Which type of immune response is responsible for Allergic Contact Dermatitis?

<p>Type IV immune response (D)</p> Signup and view all the answers

What is the cardinal feature of inflammation referring to irritation of nerves in inflamed tissues?

<p>Dolor (D)</p> Signup and view all the answers

What is the role of dendritic cells in the pathophysiology of Allergic Contact Dermatitis?

<p>Activation of keratinocytes (D)</p> Signup and view all the answers

Which cells are responsible for priming T cells in the pathophysiology of Allergic Contact Dermatitis?

<p>Langerhans cells and dermal DC (D)</p> Signup and view all the answers

What are the primary constituents of innate immunity in the skin?

<p>Langerhans cells and dermal DC (D)</p> Signup and view all the answers

Which type of immune response is primarily responsible for Allergic Contact Dermatitis?

<p>Cell-mediated immune response (A)</p> Signup and view all the answers

What is the main function of mast cells in the context of skin immune system?

<p>Release of inflammatory mediators (C)</p> Signup and view all the answers

What are the main functions of the skin, apart from acting as a physical barrier?

<p>Preventing insensible water loss and controlling body temperature (D)</p> Signup and view all the answers

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