Podcast
Questions and Answers
What is inflammation?
What is inflammation?
A defense reaction of living tissue against damage, aimed at removing the cause of injury and repairing the tissue.
What are the two types of inflammation?
What are the two types of inflammation?
Acute and chronic inflammation
Which of the following is an endogenous cause of inflammation?
Which of the following is an endogenous cause of inflammation?
- Thermal burns
- thrombosis (correct)
- Fractures
- Bacterial infection
What physical agent is an exogenous cause of inflammation?
What physical agent is an exogenous cause of inflammation?
Match to the correct Exogenous agents
Match to the correct Exogenous agents
What are the exogenous biological agents?
What are the exogenous biological agents?
What are the two endogenous causes?
What are the two endogenous causes?
What are the 7 mediators of inflammation?
What are the 7 mediators of inflammation?
Which of the following are pro-inflammatory cytokines?
Which of the following are pro-inflammatory cytokines?
Which of the pro-inflammatory cytokines is responsible for inducing fever and stress hormone production?
Which of the pro-inflammatory cytokines is responsible for inducing fever and stress hormone production?
Which proinflammatory cytokines are responsible for inducing the synthesis of IL-6, IL-8 and interferon gamma?
Which proinflammatory cytokines are responsible for inducing the synthesis of IL-6, IL-8 and interferon gamma?
Which of the following mediators is responsible for promoting acute phase protein release?
Which of the following mediators is responsible for promoting acute phase protein release?
IL-1, IL-6 and IL-8 promote ________, _______ and __________
IL-1, IL-6 and IL-8 promote ________, _______ and __________
What is the role of C3b and C5a in the complement system during inflammation?
What is the role of C3b and C5a in the complement system during inflammation?
Complement components also stimulate chemotaxis of __________, ___________ and ____________
Complement components also stimulate chemotaxis of __________, ___________ and ____________
What role does prostaglandin E2 (PGE2) play during inflammation?
What role does prostaglandin E2 (PGE2) play during inflammation?
Prostaglandins contribute to _________, ___________, _________ and ________ during inflammation
Prostaglandins contribute to _________, ___________, _________ and ________ during inflammation
Thromboxane A2 promotes platelet aggregation and inhibits vasoconstriction
Thromboxane A2 promotes platelet aggregation and inhibits vasoconstriction
Which eicosanoid is directly responsible for causing bronchoconstriction during inflammation?
Which eicosanoid is directly responsible for causing bronchoconstriction during inflammation?
LTC4, LTD4 and LTE4 induce smooth muscle contraction
LTC4, LTD4 and LTE4 induce smooth muscle contraction
Which of the following inflammatory mediators are known as the “slow reacting substances of anaphylaxis”?
Which of the following inflammatory mediators are known as the “slow reacting substances of anaphylaxis”?
What are the two vasoactive amines mentioned in the lecture?
What are the two vasoactive amines mentioned in the lecture?
What type of cells are vasoactive amine found at high concentration? (Hint: 3 cells)
What type of cells are vasoactive amine found at high concentration? (Hint: 3 cells)
What are the two plasma proteases?
What are the two plasma proteases?
Which of the following is not true about Platelet Activating Factor’s functions?
Which of the following is not true about Platelet Activating Factor’s functions?
Which phase of the vascular stage of inflammation involves initial vasoconstriction?
Which phase of the vascular stage of inflammation involves initial vasoconstriction?
Which stage of inflammation is characterized by increased vascular permeability and swelling?
Which stage of inflammation is characterized by increased vascular permeability and swelling?
What happens during the active vasodilation phase of inflammation?
What happens during the active vasodilation phase of inflammation?
Which stage of inflammation directly follows the cellular stage and involves removal of pathogens and tissue repair?
Which stage of inflammation directly follows the cellular stage and involves removal of pathogens and tissue repair?
Match to the following sequence of events for the cellular response
Match to the following sequence of events for the cellular response
What four cells are the first cells to arrive at the site of infection of the innate immunity during leukocyte trafficking ?
What four cells are the first cells to arrive at the site of infection of the innate immunity during leukocyte trafficking ?
Cells of a given tissue are held together by _________
Cells of a given tissue are held together by _________
During infammation, ________ cause changes in adhesion molecules on the ________ cells and leukocytes
During infammation, ________ cause changes in adhesion molecules on the ________ cells and leukocytes
In order for the cells of the immune system to participate in the inflammatory response, they need to use ___ to migrate to tissues where inflammation takes place
In order for the cells of the immune system to participate in the inflammatory response, they need to use ___ to migrate to tissues where inflammation takes place
CAMs are only expressed on endothelium
CAMs are only expressed on endothelium
What are the four types of Cell Adhesion Molecules?
What are the four types of Cell Adhesion Molecules?
What are the important selectins in extravasation ?
What are the important selectins in extravasation ?
Selectins bind to ____________
Selectins bind to ____________
Selectin ___ and ___ are expressed on the endothelium during inflammation
Selectin ___ and ___ are expressed on the endothelium during inflammation