Irritable Bowel Syndrome and Chronic Idiopathic Constipation
48 Questions
0 Views

Irritable Bowel Syndrome and Chronic Idiopathic Constipation

Created by
@NicestInterstellar

Podcast Beta

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What are the three categories of antidiarrheal medications mentioned in the text?

  • Anti-motility, adsorbents, and agents that modify fluid and electrolyte transport (correct)
  • Anti-inflammatory, analgesics, and corticosteroids
  • Antacids, laxatives, and proton pump inhibitors
  • Antibiotics, probiotics, and antivirals

    • What is a common cause of noninfectious diarrhea mentioned in the text?

  • Viral infection
  • Fluid absorption from the gut
  • Bacterial infection
  • Increased GI motility (correct)

    • What is the objective of integrating knowledge about drugs used to treat irritable bowel syndrome?

  • To understand mechanisms of action of antibiotics
  • To increase awareness about viral infection
  • To promote the use of laxatives
  • To ensure appropriate use of drugs for irritable bowel syndrome (correct)

    • Which condition can drugs be used to treat based on the objectives mentioned in the text?

    <p>Diverticulitis</p> Signup and view all the answers

    What is the main focus of integrating knowledge about drugs used to treat inflammatory bowel disease?

    <p>To ensure appropriate use of drugs for inflammatory bowel disease</p> Signup and view all the answers

    What can cause diarrhea besides bacterial or viral infection according to the text?

    <p>Stress and anxiety</p> Signup and view all the answers

    Which of the following is an appropriate concern when using diphenoxylate + atropine (Lomotil) for diarrhea treatment?

    <p>Treatment of infectious diarrhea</p> Signup and view all the answers

    What is the main concern associated with the use of loperamide (Immodium A-D) for diarrhea treatment?

    <p>Treatment of infectious diarrhea</p> Signup and view all the answers

    What is a common side effect associated with adsorbents used for diarrhea treatment?

    <p>Fecal discoloration</p> Signup and view all the answers

    What is the main concern regarding the use of bismuth subsalicylate (Pepto-Bismol) for diarrhea treatment?

    <p>Usage in children</p> Signup and view all the answers

    Which class of antibiotics has a high association with causing C. difficile infection?

    <p>Cephalosporins</p> Signup and view all the answers

    What is the treatment of choice for C. difficile infection, which interacts with DNA to cause inhibition of protein synthesis and cell death?

    <p>Metronidazole (Flagyl)</p> Signup and view all the answers

    What is the mechanism of action of 6-Mercaptopurine (Purixan) in the treatment of ulcerative colitis?

    <p>Inhibition of DNA and RNA synthesis</p> Signup and view all the answers

    What is the main concern when using Azathioprine (Imuran) for the treatment of ulcerative colitis?

    <p>Test for thiopurine methyltransferase (TPMT) activity</p> Signup and view all the answers

    Which medication is contraindicated in patients with heart failure due to an increased risk for infection and TB?

    <p>Adalimumab (Humira)</p> Signup and view all the answers

    What is the mechanism of action of Methotrexate in the treatment of Crohn’s disease?

    <p>Folate antimetabolite that inhibits DNA synthesis, repair, and cellular replication</p> Signup and view all the answers

    Which biologic agent is a monoclonal antibody that binds to the alpha-4 subunit of integrin molecules that prevents transmigration of leukocytes?

    <p>Natalizumab (Tysabri)</p> Signup and view all the answers

    What is the main concern when using Tofacitinib (Xeljanz) for the treatment of ulcerative colitis?

    <p>CYP3A4 interactions</p> Signup and view all the answers

    What is the mechanism of action of Lubiprostone?

    <p>Agonist of guanylate cyclase-C</p> Signup and view all the answers

    Which medication is limited to women with severe diarrhea-predominant IBS due to concerns about ischemic colitis?

    <p>Linaclotide (Linzess)</p> Signup and view all the answers

    What is the main side effect of Plecanatide (Trulance)?

    <p>Abdominal distension</p> Signup and view all the answers

    What is the mechanism of action of Eluxadoline (Viberzi)?

    <p>Mixed mu-opioid receptor agonist</p> Signup and view all the answers

    What is the most common side effect of Bisacodyl (Dulcolax)?

    <p>Bloating</p> Signup and view all the answers

    What is the MOA of Prucalopride (Motegrity)?

    <p>Selective, high affinity 5-HT4 receptor agonist promoting cholinergic neurotransmission by enteric neurons</p> Signup and view all the answers

    What are the two most common functional GI disorders worldwide?

    <p>Irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC)</p> Signup and view all the answers

    What is the basis for subtyping IBS?

    <p>Predominant bowel habit</p> Signup and view all the answers

    According to the text, what is the socioeconomic impact of IBS?

    <p>Considerable impact due to associated debility and prevalence</p> Signup and view all the answers

    What is the basis for classifying IBS according to bowel habit type?

    <p>Stool form described by the patient using the Bristol Stool Scale</p> Signup and view all the answers

    How is chronic idiopathic constipation (CIC) characterized?

    <p>Not associated with abnormal radiologic or endoscopic abnormalities or a reliable biomarker</p> Signup and view all the answers

    In what age group does IBS typically occur?

    <p>Younger adulthood</p> Signup and view all the answers

    What is the mechanism of action of sulfamethoxazole + trimethoprim (Bactrim)?

    <p>Sequential inhibition of enzymes of the folic acid pathway</p> Signup and view all the answers

    What is the most common side effect of ciprofloxacin (Cipro)?

    <p>Dizziness</p> Signup and view all the answers

    Which antibiotic should be avoided in patients with a history of seizures?

    <p>Meropenem (Merrem)</p> Signup and view all the answers

    Which antibiotic combination is commonly used for inpatient treatment of diverticulitis?

    <p>Metronidazole plus Ciprofloxacin</p> Signup and view all the answers

    What is the primary concern with the use of sulfamethoxazole + trimethoprim (Bactrim) in neonates?

    <p>Do NOT given to neonates</p> Signup and view all the answers

    Which antibiotic inhibits bacterial cell wall synthesis by binding one or more penicillin-binding proteins (PBPs)?

    <p>Cefotaxime (Claforan)</p> Signup and view all the answers

    What is the most common side effect of metronidazole (Flagyl)?

    <p>Metallic taste</p> Signup and view all the answers

    What is the primary concern with the use of metronidazole (Flagyl)?

    <p>NO ALCOHOL while taking and for 3 days after stopping the medication</p> Signup and view all the answers

    Which antibiotic should be used for diverticulitis inpatient treatment if the patient is allergic to penicillin?

    <p>Ciprofloxacin</p> Signup and view all the answers

    What is the appropriate antipseudomonal penicillin for diverticulitis inpatient treatment?

    <p>Piperacillin-Tazobactam</p> Signup and view all the answers

    Which antibiotic combination is suitable for diverticulitis inpatient treatment for Pseudomonas coverage?

    <p>Ciprofloxacin + Metronidazole</p> Signup and view all the answers

    Which antibiotic should be avoided in neonates with diverticulitis?

    <p>Ceftriaxone</p> Signup and view all the answers

    What is the correct antibiotic regimen for outpatient treatment of uncomplicated diverticulitis?

    <p>Amoxicillin/Clavulanate alone</p> Signup and view all the answers

    Which antibiotic should not be taken with multivitamins, calcium, iron, or dairy products?

    <p>Ciprofloxacin</p> Signup and view all the answers

    What is the antibiotic of choice for diverticulitis inpatient treatment if the patient has a history of seizures?

    <p>Meropenem</p> Signup and view all the answers

    What is the appropriate antibiotic regimen for diverticulitis inpatient treatment if the patient has renal impairment?

    <p>Piperacillin-Tazobactam + Cefotaxime</p> Signup and view all the answers

    Which antibiotic should be avoided in children for the treatment of diverticulitis?

    <p>Ciprofloxacin</p> Signup and view all the answers

    Which antibiotic has a disulfiram-like reaction as a potential side effect?

    <p>Metronidazole</p> Signup and view all the answers

    More Like This

    Irritable Bowel Syndrome Treatment and Types
    38 questions

    Irritable Bowel Syndrome Treatment and Types

    NicestInterstellar avatar
    NicestInterstellar
    Treatment of Irritable Bowel Syndrome with GI Medications
    45 questions

    Treatment of Irritable Bowel Syndrome with GI Medications

    BoundlessObsidian4130 avatar
    BoundlessObsidian4130
    Irritable Bowel Syndrome Overview
    59 questions

    Irritable Bowel Syndrome Overview

    TerrificHawthorn337 avatar
    TerrificHawthorn337
    Irritable Bowel Syndrome Overview
    68 questions

    Irritable Bowel Syndrome Overview

    FormidablePennywhistle avatar
    FormidablePennywhistle
    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser