Podcast
Questions and Answers
What is the primary reason for Tenapanor (Ibsrela) being contraindicated in patients?
What is the primary reason for Tenapanor (Ibsrela) being contraindicated in patients?
- It leads to dizziness and syncope
- It inhibits the absorption of dietary sodium (correct)
- It causes severe diarrhea
- It is not present in breastmilk
Which adverse effect has been reported in some cases associated with Linacotide use?
Which adverse effect has been reported in some cases associated with Linacotide use?
- Severe diarrhea requiring IV fluids (correct)
- Hypertension and tachycardia
- Bradypnea and bronchoconstriction
- Dizziness and syncope
What is a key benefit of Tenapanor (Ibsrela) in the treatment of IBS-C?
What is a key benefit of Tenapanor (Ibsrela) in the treatment of IBS-C?
- Reduces abdominal pain (correct)
- Increases visceral hypersensitivity
- Blocks absorption of water
- Induces constipation
Why should the decision to breastfeed during therapy with Linacotide be carefully considered?
Why should the decision to breastfeed during therapy with Linacotide be carefully considered?
What does Tenapanor target to achieve its therapeutic effect in IBS-C?
What does Tenapanor target to achieve its therapeutic effect in IBS-C?
Which of the following statements about Linacotide is true?
Which of the following statements about Linacotide is true?
What is the mechanism of action of Tenapanor (Ibsrela) in blocking sodium absorption?
What is the mechanism of action of Tenapanor (Ibsrela) in blocking sodium absorption?
Why is careful consideration needed for the decision to breastfeed during Tenapanor therapy?
Why is careful consideration needed for the decision to breastfeed during Tenapanor therapy?
What is the primary goal of using antispasmodic drugs in the treatment of IBS?
What is the primary goal of using antispasmodic drugs in the treatment of IBS?
Which of the following is NOT a common anticholinergic side effect associated with antispasmodic drugs?
Which of the following is NOT a common anticholinergic side effect associated with antispasmodic drugs?
How do serotonin 5-HT-3 receptor antagonists work in the treatment of IBS?
How do serotonin 5-HT-3 receptor antagonists work in the treatment of IBS?
What led to alosetron being taken off the market in 2000?
What led to alosetron being taken off the market in 2000?
Under what strategy was alosetron reintroduced to the market in 2002?
Under what strategy was alosetron reintroduced to the market in 2002?
What is a common adverse effect associated with linaclotide, a guanylate cyclase-C agonist?
What is a common adverse effect associated with linaclotide, a guanylate cyclase-C agonist?
Why is linaclotide contraindicated in pediatric patients younger than 2 years?
Why is linaclotide contraindicated in pediatric patients younger than 2 years?
What is the US Boxed Warning for Tenapanor (Ibsrela)?
What is the US Boxed Warning for Tenapanor (Ibsrela)?
Which of the following is a potential drug interaction associated with Linacotide?
Which of the following is a potential drug interaction associated with Linacotide?
What is a significant warning associated with the use of Linacotide?
What is a significant warning associated with the use of Linacotide?
Which adverse effect has NOT been reported with the use of Linacotide?
Which adverse effect has NOT been reported with the use of Linacotide?
What is a concern related to the use of Linacotide during breastfeeding?
What is a concern related to the use of Linacotide during breastfeeding?
Which statement best describes the FDA indications for Linacotide?
Which statement best describes the FDA indications for Linacotide?
Why is careful monitoring required when using Linacotide?
Why is careful monitoring required when using Linacotide?
What is the FDA indication for linaclotide?
What is the FDA indication for linaclotide?
Which of the following is a US boxed warning associated with linaclotide?
Which of the following is a US boxed warning associated with linaclotide?
Which type of patients should linaclotide be reserved for?
Which type of patients should linaclotide be reserved for?
What is a potential adverse effect associated with linaclotide use?
What is a potential adverse effect associated with linaclotide use?
Which of the following is NOT a common drug interaction associated with linaclotide?
Which of the following is NOT a common drug interaction associated with linaclotide?
Why is linaclotide contraindicated in pediatric patients younger than 2 years?
Why is linaclotide contraindicated in pediatric patients younger than 2 years?
What is a common adverse effect of linaclotide that can sometimes be severe?
What is a common adverse effect of linaclotide that can sometimes be severe?
Which of the following is a notable warning associated with linaclotide use?
Which of the following is a notable warning associated with linaclotide use?
What is the most concerning potential adverse effect associated with linaclotide use?
What is the most concerning potential adverse effect associated with linaclotide use?
In terms of drug interactions, which statement accurately reflects the known interactions with linaclotide?
In terms of drug interactions, which statement accurately reflects the known interactions with linaclotide?
What is the FDA indication for linaclotide use?
What is the FDA indication for linaclotide use?
What is the US Boxed Warning associated with Tenapanor (Ibsrela)?
What is the US Boxed Warning associated with Tenapanor (Ibsrela)?
Which of the following is a possible adverse effect requiring hospitalization in some cases of linaclotide use?
Which of the following is a possible adverse effect requiring hospitalization in some cases of linaclotide use?
Why should the decision to breastfeed during treatment with linaclotide be carefully considered?
Why should the decision to breastfeed during treatment with linaclotide be carefully considered?
Which of the following accurately describes a concern related to linaclotide use during breastfeeding?
Which of the following accurately describes a concern related to linaclotide use during breastfeeding?
What is a potential adverse effect of linaclotide that is sometimes severe?
What is a potential adverse effect of linaclotide that is sometimes severe?
Which of the following is not a common drug interaction associated with linaclotide?
Which of the following is not a common drug interaction associated with linaclotide?
What is a notable warning associated with linaclotide use?
What is a notable warning associated with linaclotide use?
What is a significant adverse effect reported in some cases associated with linaclotide use?
What is a significant adverse effect reported in some cases associated with linaclotide use?
Which of the following statements about linaclotide is true?
Which of the following statements about linaclotide is true?
What is the FDA indication for linaclotide?
What is the FDA indication for linaclotide?
What is the US boxed warning for linaclotide?
What is the US boxed warning for linaclotide?
Why is careful monitoring required when using linaclotide?
Why is careful monitoring required when using linaclotide?
