Podcast
Questions and Answers
What is the mechanism of action of 6-Mercaptopurine (Purixan) in the treatment of ulcerative colitis?
What is the mechanism of action of 6-Mercaptopurine (Purixan) in the treatment of ulcerative colitis?
- Binding to alpha4beta7 integrin
- Inhibition of Janus kinase
- Inhibition of DNA and RNA synthesis (correct)
- Interference with TNF alpha activity
Which side effect is commonly associated with the use of Infliximab (Remicade) in the treatment of ulcerative colitis?
Which side effect is commonly associated with the use of Infliximab (Remicade) in the treatment of ulcerative colitis?
- Injection site reaction
- Increased liver enzymes
- Dizziness
- Headache (correct)
What is the main concern when using Vedolizumab (Entyvio) in the treatment of ulcerative colitis?
What is the main concern when using Vedolizumab (Entyvio) in the treatment of ulcerative colitis?
- Injection site reactions
- Development of PML
- CYP3A4 interactions
- Hypersensitivity reactions (correct)
Which medication is contraindicated in patients with heart failure in the treatment of ulcerative colitis?
Which medication is contraindicated in patients with heart failure in the treatment of ulcerative colitis?
What is the primary concern when using Certolizumab Pegol (Cimzia) in the treatment of Crohn’s disease?
What is the primary concern when using Certolizumab Pegol (Cimzia) in the treatment of Crohn’s disease?
Which class of medications can exacerbate Crohn’s disease?
Which class of medications can exacerbate Crohn’s disease?
What is the mechanism of action of loperamide (Immodium A-D)?
What is the mechanism of action of loperamide (Immodium A-D)?
Which medication is contraindicated for the treatment of infectious diarrhea?
Which medication is contraindicated for the treatment of infectious diarrhea?
What is one of the concerns associated with the use of bismuth subsalicylate (Pepto-Bismol)?
What is one of the concerns associated with the use of bismuth subsalicylate (Pepto-Bismol)?
Which antibiotic interacts with DNA to cause loss of helical DNA structure and inhibition of protein synthesis?
Which antibiotic interacts with DNA to cause loss of helical DNA structure and inhibition of protein synthesis?
What is the mechanism of action of Bezlotoxumab (Zinplava)?
What is the mechanism of action of Bezlotoxumab (Zinplava)?
What are the two most common functional GI disorders worldwide?
What are the two most common functional GI disorders worldwide?
What is the basis for subtyping IBS?
What is the basis for subtyping IBS?
What does IBS typically occur in?
What does IBS typically occur in?
What is the socioeconomic impact of IBS?
What is the socioeconomic impact of IBS?
What is used as the basis for classifying the bowel habit type in IBS?
What is used as the basis for classifying the bowel habit type in IBS?
Which of the following is not a sub-type of IBS?
Which of the following is not a sub-type of IBS?
Which of the following is not a category of antidiarrheal medication?
Which of the following is not a category of antidiarrheal medication?
Which condition can be caused by increased GI motility or decreased fluid absorption from the gut?
Which condition can be caused by increased GI motility or decreased fluid absorption from the gut?
What is the primary objective of integrating knowledge about drugs used to treat inflammatory bowel disease?
What is the primary objective of integrating knowledge about drugs used to treat inflammatory bowel disease?
Which category of drugs is used to treat diverticulitis?
Which category of drugs is used to treat diverticulitis?
What is a potential cause of diarrhea besides bacterial or viral infection?
What is a potential cause of diarrhea besides bacterial or viral infection?
What is the main focus of integrating knowledge about drugs used to treat irritable bowel syndrome?
What is the main focus of integrating knowledge about drugs used to treat irritable bowel syndrome?
Which medication for IBS acts as an agonist of guanylate cyclase-C, resulting in increased intestinal fluid and decreased GI transit time?
Which medication for IBS acts as an agonist of guanylate cyclase-C, resulting in increased intestinal fluid and decreased GI transit time?
What is the main concern associated with the use of Alosetron (Lotronex) in treating IBS?
What is the main concern associated with the use of Alosetron (Lotronex) in treating IBS?
Which medication for IBS acts as a mixed mu-opioid receptor agonist, delta opioid receptor antagonist, and kappa opioid receptor agonist?
Which medication for IBS acts as a mixed mu-opioid receptor agonist, delta opioid receptor antagonist, and kappa opioid receptor agonist?
Which medication for IBS should not be used in those who drink more than 3 glasses of alcohol per day?
Which medication for IBS should not be used in those who drink more than 3 glasses of alcohol per day?
Which medication for CIC is administered immediately prior to breakfast or the first meal of the day and immediately prior to dinner?
Which medication for CIC is administered immediately prior to breakfast or the first meal of the day and immediately prior to dinner?
Which medication for CIC acts as an osmotic agent that causes water retention in the stool and increases stool frequency?
Which medication for CIC acts as an osmotic agent that causes water retention in the stool and increases stool frequency?
Which antibiotic combination is used for inpatient treatment of diverticulitis?
Which antibiotic combination is used for inpatient treatment of diverticulitis?
What is the mechanism of action of Ciprofloxacin (Cipro)?
What is the mechanism of action of Ciprofloxacin (Cipro)?
What are the concerns associated with the use of Metronidazole (Flagyl)?
What are the concerns associated with the use of Metronidazole (Flagyl)?
Which antibiotic is a combination drug with a beta-lactam antibiotic plus a beta-lactamase inhibitor?
Which antibiotic is a combination drug with a beta-lactam antibiotic plus a beta-lactamase inhibitor?
What is the mechanism of action of Moxifloxacin (Avelox)?
What is the mechanism of action of Moxifloxacin (Avelox)?
Which antibiotic should be avoided in neonates (ï‚£28 days)?
Which antibiotic should be avoided in neonates (ï‚£28 days)?
Which antibiotic is an IV antipseudomonal PCN?
Which antibiotic is an IV antipseudomonal PCN?
What is the primary concern associated with Meropenem (Merrem)?
What is the primary concern associated with Meropenem (Merrem)?
(Bactrim) is composed of which antibiotics?
(Bactrim) is composed of which antibiotics?
