Podcast
Questions and Answers
Autoimmune diseases occur due to the immune system attacking non-self cells
Autoimmune diseases occur due to the immune system attacking non-self cells
False
Autoimmune diseases can be directed against a very specific tissue or a large number of tissues
Autoimmune diseases can be directed against a very specific tissue or a large number of tissues
True
More women than men are affected by autoimmune diseases
More women than men are affected by autoimmune diseases
True
Autoimmune diseases are caused by the presence of autoantibodies or autoreactive cells
Autoimmune diseases are caused by the presence of autoantibodies or autoreactive cells
Signup and view all the answers
The immune system ensures self-tolerance by promoting the development of auto-reactive lymphocytes
The immune system ensures self-tolerance by promoting the development of auto-reactive lymphocytes
Signup and view all the answers
Rheumatoid arthritis is an example of an immunodeficiency disease.
Rheumatoid arthritis is an example of an immunodeficiency disease.
Signup and view all the answers
Rheumatism only affects the joints and not the connective tissue.
Rheumatism only affects the joints and not the connective tissue.
Signup and view all the answers
MHC class I genes are associated with Rheumatoid Arthritis.
MHC class I genes are associated with Rheumatoid Arthritis.
Signup and view all the answers
Viral infections are not considered as environmental factors that predispose to Rheumatologic Diseases.
Viral infections are not considered as environmental factors that predispose to Rheumatologic Diseases.
Signup and view all the answers
Chronic Arthritis is a term used to describe the long-term inflammation of a joint.
Chronic Arthritis is a term used to describe the long-term inflammation of a joint.
Signup and view all the answers
Study Notes
- Autoimmune diseases are abnormal conditions where self-cells are attacked by autoantibodies or autoreactive cells
- Immune system normally eliminates auto-reactive lymphocytes during development, but this process fails in autoimmune diseases
- Attack can be humoral (by auto-antibodies) or cellular (by auto-reactive T cells)
- Can be specific to a tissue or systemic, depending on the self-antigen targeted
- Prevalence: 5-7% of adults are affected, with two thirds being women. Over 80 human diseases have autoimmune origins.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Learn about the definition, etiology, mechanisms, and diagnosis of autoimmune diseases in this lecture. Understand how the immune system can attack the body and the role of auto-reactive lymphocytes.
