Podcast
Questions and Answers
Autoimmune diseases occur due to the immune system attacking non-self cells
Autoimmune diseases occur due to the immune system attacking non-self cells
False (B)
Autoimmune diseases can be directed against a very specific tissue or a large number of tissues
Autoimmune diseases can be directed against a very specific tissue or a large number of tissues
True (A)
More women than men are affected by autoimmune diseases
More women than men are affected by autoimmune diseases
True (A)
Autoimmune diseases are caused by the presence of autoantibodies or autoreactive cells
Autoimmune diseases are caused by the presence of autoantibodies or autoreactive cells
The immune system ensures self-tolerance by promoting the development of auto-reactive lymphocytes
The immune system ensures self-tolerance by promoting the development of auto-reactive lymphocytes
Rheumatoid arthritis is an example of an immunodeficiency disease.
Rheumatoid arthritis is an example of an immunodeficiency disease.
Rheumatism only affects the joints and not the connective tissue.
Rheumatism only affects the joints and not the connective tissue.
MHC class I genes are associated with Rheumatoid Arthritis.
MHC class I genes are associated with Rheumatoid Arthritis.
Viral infections are not considered as environmental factors that predispose to Rheumatologic Diseases.
Viral infections are not considered as environmental factors that predispose to Rheumatologic Diseases.
Chronic Arthritis is a term used to describe the long-term inflammation of a joint.
Chronic Arthritis is a term used to describe the long-term inflammation of a joint.
Study Notes
- Autoimmune diseases are abnormal conditions where self-cells are attacked by autoantibodies or autoreactive cells
- Immune system normally eliminates auto-reactive lymphocytes during development, but this process fails in autoimmune diseases
- Attack can be humoral (by auto-antibodies) or cellular (by auto-reactive T cells)
- Can be specific to a tissue or systemic, depending on the self-antigen targeted
- Prevalence: 5-7% of adults are affected, with two thirds being women. Over 80 human diseases have autoimmune origins.
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Description
Learn about the definition, etiology, mechanisms, and diagnosis of autoimmune diseases in this lecture. Understand how the immune system can attack the body and the role of auto-reactive lymphocytes.
