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Questions and Answers
What type of cells are primarily infected by the HPV virus?
What type of cells are primarily infected by the HPV virus?
How does HPV typically cause warts to form?
How does HPV typically cause warts to form?
What is a common mode of transmission for HPV?
What is a common mode of transmission for HPV?
Which of the following is a risk factor associated with HPV infection?
Which of the following is a risk factor associated with HPV infection?
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What does HPV do to keratinocytes during infection?
What does HPV do to keratinocytes during infection?
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Which symptoms are indicative of shingles caused by the Varicella-Zoster Virus?
Which symptoms are indicative of shingles caused by the Varicella-Zoster Virus?
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What is a primary risk factor for developing chickenpox?
What is a primary risk factor for developing chickenpox?
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How does Herpes Simplex Virus typically enter the body?
How does Herpes Simplex Virus typically enter the body?
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What condition is associated with the Human Papillomavirus?
What condition is associated with the Human Papillomavirus?
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What is a common trigger for the reactivation of Herpes Simplex Virus?
What is a common trigger for the reactivation of Herpes Simplex Virus?
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What is a characteristic feature of chickenpox caused by the Varicella-Zoster Virus?
What is a characteristic feature of chickenpox caused by the Varicella-Zoster Virus?
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What is the main mode of transmission for HSV-1?
What is the main mode of transmission for HSV-1?
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Individuals at higher risk for shingles include those who are:
Individuals at higher risk for shingles include those who are:
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Study Notes
Integumentary - Viral Skin Infections
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Varicella-Zoster Virus (Chickenpox & Shingles):
- Caused by the Varicella-Zoster Virus (VZV), part of the Herpesvirus family.
- Chickenpox: Enters respiratory tract, spreads to bloodstream, leading to a generalized vesicular rash.
- Shingles: Virus remains dormant in nerve ganglia. Reactivation typically occurs in older adults or immunocompromised individuals, causing a painful vesicular rash in a dermatomal distribution.
- Transmission: Highly contagious, spread by airborne droplets or direct contact with vesicle fluid.
- Risk Factors (Chickenpox): Contact with infected individuals, lack of vaccination, childhood or adulthood with no prior infection.
- Risk Factors (Shingles): Older age, immunosuppression, stress or a history of chicken pox.
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Herpes Simplex Virus (HSV):
- Caused by Herpes Simplex Virus type 1 (HSV-1, oral herpes) and Herpes Simplex Virus type 2 (HSV-2, genital herpes).
- Pathophysiology: After initial infection, virus enters sensory neurons, becomes dormant in dorsal root ganglion. Reactivation due to stress, trauma, or immunosuppression can cause painful vesicular eruptions (cold sores or genital herpes) on the skin.
- Transmission: Direct contact with lesions, saliva, or genital secretions. HSV-1 often transmitted by kissing or sharing personal items (e.g., lip balm); HSV-2 transmitted through sexual contact.
- Risk Factors: Direct contact with infected individuals, weakened immune system, sharing personal items, or unprotected sexual contact.
Human Papillomavirus (HPV)
- Cause: Caused by Human Papillomavirus (HPV). Different strains cause different diseases (e.g., common warts, plantar warts, genital warts).
- Pathophysiology: Infects keratinocytes (skin cells) and mucosa. Promotes keratinocyte proliferation, leading to thickened growths (warts) on skin or mucosa. Can remain latent and reactivate, causing recurrent warts.
- Transmission: Direct contact with infected skin or mucosa, or exposure to contaminated surfaces (e.g., swimming pools, showers).
- Risk Factors: Contact with infected surfaces, immunosuppression, sexual contact (genital warts), and use of shared surfaces.
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Description
This quiz explores viral skin infections, focusing on the Varicella-Zoster Virus responsible for chickenpox and shingles. It also covers the Herpes Simplex Virus types 1 and 2. Understand the transmission, risk factors, and impacts of these infections on the integumentary system.
