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Questions and Answers
What is a prerequisite for a viral skin infection?
What is a prerequisite for a viral skin infection?
- Contact with other infected animals
- Intact skin barrier
- Antropod bite or wound (correct)
- Immunization against the virus
Which of the following lesions is classified as neoplastic?
Which of the following lesions is classified as neoplastic?
- Vesicular lesions from FMD
- Ulcers from contagious ecthyma
- Pustules from poxvirus
- Papilloma (correct)
What is a characteristic of poxviral infections?
What is a characteristic of poxviral infections?
- Formation of intranuclear inclusion bodies
- Thickened dermis with fibrosis
- Development of umbilicated pustules (correct)
- Presence of flat, raised crusty masses
Which histological feature is associated with poxviral infections?
Which histological feature is associated with poxviral infections?
What type of papilloma is specifically mentioned in the context of viral diseases?
What type of papilloma is specifically mentioned in the context of viral diseases?
What characteristic is observed in the histopathology of contagious ecthyma?
What characteristic is observed in the histopathology of contagious ecthyma?
What type of lesions are associated with contagious ecthyma?
What type of lesions are associated with contagious ecthyma?
What is a notable feature of histopathological findings related to ballooning degeneration?
What is a notable feature of histopathological findings related to ballooning degeneration?
What type of cells are notably increased in number within the lesions of contagious ecthyma?
What type of cells are notably increased in number within the lesions of contagious ecthyma?
What is the typical appearance of lesions during the progression of poxvirus skin lesions?
What is the typical appearance of lesions during the progression of poxvirus skin lesions?
In the gross examination of contagious pustular dermatitis, what feature is NOT typically observed?
In the gross examination of contagious pustular dermatitis, what feature is NOT typically observed?
Which histological feature is indicative of infection by certain viruses within keratinocytes?
Which histological feature is indicative of infection by certain viruses within keratinocytes?
Which histological change is associated with acanthosis in skin lesions?
Which histological change is associated with acanthosis in skin lesions?
What is a characteristic feature of superficial pyoderma?
What is a characteristic feature of superficial pyoderma?
Which factor does NOT assist bacteria colonization and invasion of the skin?
Which factor does NOT assist bacteria colonization and invasion of the skin?
What type of pyoderma is often chronic and may involve systemic illness?
What type of pyoderma is often chronic and may involve systemic illness?
Which microorganism is commonly associated with impetigo?
Which microorganism is commonly associated with impetigo?
What clinical appearance can characterize superficial pyoderma?
What clinical appearance can characterize superficial pyoderma?
Which bacterial disease occurs primarily in diseased skin and may involve several bacterial species?
Which bacterial disease occurs primarily in diseased skin and may involve several bacterial species?
What usually triggers the formation of vesicles in foot and mouth disease?
What usually triggers the formation of vesicles in foot and mouth disease?
What histological feature is associated with superficial pyoderma?
What histological feature is associated with superficial pyoderma?
What is the primary characteristic of canine impetigo?
What is the primary characteristic of canine impetigo?
Which of the following is a common cause of canine pyotraumatic dermatitis?
Which of the following is a common cause of canine pyotraumatic dermatitis?
What is the causative agent of 'Diamond Skin Disease' in pigs?
What is the causative agent of 'Diamond Skin Disease' in pigs?
What type of dermatitis is characterized by branching filaments and is often seen in hot and humid areas?
What type of dermatitis is characterized by branching filaments and is often seen in hot and humid areas?
What typically predisposes an animal to canine impetigo?
What typically predisposes an animal to canine impetigo?
Which of the following describes the severity of feline acne as it progresses?
Which of the following describes the severity of feline acne as it progresses?
What kind of infections are caused by Microsporum spp. and Trichophyton spp.?
What kind of infections are caused by Microsporum spp. and Trichophyton spp.?
What is the histological feature associated with sporotrichosis?
What is the histological feature associated with sporotrichosis?
What are the typical clinical manifestations of sporotrichosis?
What are the typical clinical manifestations of sporotrichosis?
What is a common effect of endotoxin-induced venous thrombosis due to Salmonellosis?
What is a common effect of endotoxin-induced venous thrombosis due to Salmonellosis?
Which of the following is NOT associated with deep mycoses?
Which of the following is NOT associated with deep mycoses?
What type of fungi primarily cause subcutaneous or intermediate mycoses?
What type of fungi primarily cause subcutaneous or intermediate mycoses?
What is observed through the PAS stain in cases of sporotrichosis?
What is observed through the PAS stain in cases of sporotrichosis?
What is the primary characteristic appearance of lesions caused by dermatophytosis?
What is the primary characteristic appearance of lesions caused by dermatophytosis?
Which of the following factors predisposes animals to dermatophytosis?
Which of the following factors predisposes animals to dermatophytosis?
What is a common cause of alopecia in dermatophytosis?
What is a common cause of alopecia in dermatophytosis?
What type of fungi is primarily associated with dermatophytosis?
What type of fungi is primarily associated with dermatophytosis?
What histological feature is associated with the early phase of contact irritant dermatitis in dermatophytosis?
What histological feature is associated with the early phase of contact irritant dermatitis in dermatophytosis?
Where can arthrospores be found in cases of dermatophytosis?
Where can arthrospores be found in cases of dermatophytosis?
What is the mechanism by which dermatophytes affect hair follicles?
What is the mechanism by which dermatophytes affect hair follicles?
What can result from secondary bacterial folliculitis due to dermatophytosis?
What can result from secondary bacterial folliculitis due to dermatophytosis?
Flashcards
How do viruses infect the skin?
How do viruses infect the skin?
Viral infections of the skin can occur when the skin barrier is compromised, allowing viruses to enter.
What are papillomaviruses?
What are papillomaviruses?
Papillomaviruses are a group of viruses that cause skin growths called papillomas. They are epitheliotropic, meaning they infect epithelial cells, which are the cells that line surfaces, including skin.
Describe the progression of poxvirus lesions.
Describe the progression of poxvirus lesions.
Poxviruses cause skin lesions that progress through different stages: erythema (redness), papules (raised bumps), vesicles (fluid-filled blisters), pustules (pus-filled blisters), ulceration, and crust formation. The healing process often leaves scars.
What are papillomas?
What are papillomas?
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What are the characteristics of poxvirus infections?
What are the characteristics of poxvirus infections?
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Ballooning Degeneration
Ballooning Degeneration
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Intracytoplasmic Inclusion Bodies
Intracytoplasmic Inclusion Bodies
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Poxvirus Lesions
Poxvirus Lesions
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Hyperkeratosis
Hyperkeratosis
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Spongiosis
Spongiosis
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Contagious Ecthyma
Contagious Ecthyma
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Acanthosis
Acanthosis
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Intracytoplasmic Inclusion Bodies
Intracytoplasmic Inclusion Bodies
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Skin Barrier Resistance
Skin Barrier Resistance
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Damaged Skin Barrier and Bacterial Infections
Damaged Skin Barrier and Bacterial Infections
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Moisture and Bacterial Colonization
Moisture and Bacterial Colonization
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Keratinization Alterations and Bacterial Infections
Keratinization Alterations and Bacterial Infections
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Friction, Parasites, and Bacterial Infection
Friction, Parasites, and Bacterial Infection
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Pyoderma: Bacterial Skin Infection
Pyoderma: Bacterial Skin Infection
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Superficial Pyoderma
Superficial Pyoderma
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Deep Pyoderma
Deep Pyoderma
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What are superficial mycoses?
What are superficial mycoses?
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What is the classic lesion seen in superficial mycoses?
What is the classic lesion seen in superficial mycoses?
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What is Dermatophytosis?
What is Dermatophytosis?
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What are the common causative agents of Dermatophytosis?
What are the common causative agents of Dermatophytosis?
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What are the clinical signs of Dermatophytosis?
What are the clinical signs of Dermatophytosis?
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What is a common manifestation of Dermatophytosis in canine patients?
What is a common manifestation of Dermatophytosis in canine patients?
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What are the clinical signs of Dermatophytosis in cattle?
What are the clinical signs of Dermatophytosis in cattle?
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Can Dermatophytosis affect humans?
Can Dermatophytosis affect humans?
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Canine Impetigo
Canine Impetigo
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Dermatophilosis in Ruminants
Dermatophilosis in Ruminants
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Diamond Skin Disease in Pigs
Diamond Skin Disease in Pigs
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Canine Pyotraumatic Dermatitis
Canine Pyotraumatic Dermatitis
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Feline Acne
Feline Acne
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Salmonellosis or Other Endotoxemias
Salmonellosis or Other Endotoxemias
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Superficial Mycoses
Superficial Mycoses
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Dermatomycosis (Dermatophytosis)
Dermatomycosis (Dermatophytosis)
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What is Sporotrichosis?
What is Sporotrichosis?
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What are the microscopic features of Sporotrichosis?
What are the microscopic features of Sporotrichosis?
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What are Deep Mycoses?
What are Deep Mycoses?
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What are the histologic features of Deep Mycoses?
What are the histologic features of Deep Mycoses?
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What are Subcutaneous Mycoses?
What are Subcutaneous Mycoses?
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Study Notes
Integumentary System: Lecture 5
-
Viral Diseases of Skin (5.1):
- Intact skin is resistant to viral entry.
- Infection often requires an entry point (e.g., insect bite, wound).
- Viral infections can be local (e.g., papillomas) or systemic (e.g., viremia).
- Viral skin infections include poxviruses, papillomaviruses (causing papillomas), foot-and-mouth disease (FMD), canine distemper, and vesicular exanthema.
- Lesion types include neoplastic (e.g., papilloma), proliferative (e.g., poxvirus), and vesicular (e.g., FMD).
-
Papilloma Virus:
- Gross: lesions appear flat, raised, crusty, fissured, horny masses, attached to skin via narrow/broad pedicles.
- Histology: shows epidermal and dermal proliferation, marked epidermal thickening (hyperplasia), altered keratin layers, and sometimes inclusion bodies (rarely intracellular/extracellular).
- Types include squamous and fibropapilloma.
-
Pox Viral Infections:
- Gross: erythematous macules, papules, vesicles, pustules, ulcers, crusts, scars.
- Histology: epidermal cytoplasmic swelling, vacuolation, multiloculated vesicles, dermal edema, vascular dilation, perivascular mononuclear-cell infiltrate, variable neutrophil infiltrate.
- Different stages may show different characteristics: vesicles, pustules, crusts, and sometimes hyperplastic/proliferative lesions.
- Could be colonized by surface bacteria and show intracytoplasmic inclusion bodies.
-
Contagious Ecthyma:
- AKA Contagious Pustular Dermatitis
- Gross: skin abrasions, transient vesicles, pustules, and brown-gray crusts.
- Histology: marked keratinocyte proliferation (acanthosis), vacuolation/spongiosis, intraepidermal microabscesses, and intracytoplasmic inclusion bodies.
- Dermal changes include superficial edema, marked capillary dilation, and perivascular mononuclear infiltration.
- Lesions are generally located at feet, oral cavity areas, and eyelids.
-
Foot and Mouth Disease:
- Gross: displays vesicular lesions and erosive lesions on skin and oral mucosa.
- Histo: shows epithelial degeneration and necrosis, particularly affecting the stratum spinosum, inflammation, necrosis, and edema.
-
Vesicular Exanthema:
- Vesicles appear on snout, oral mucosa, soles of feet, coronary band, and between toes.
-
Canine Distemper:
- Clinical sign includes scaling/crusts on distal limbs.
-
Bacterial Diseases of Skin (5.2):
- Normal skin is resistant to bacterial invasion due to dryness, desquamation, and normal flora pressures.
- Damage to the skin barrier allows bacteria from transient or resident flora to cause infection.
- Factors that increase bacterial colonization and invasion include prolonged moisture, altered keratinization, physical damage, parasites, dirt, and excessive sweating.
-
Pyoderma:
- Secondary skin condition, frequently caused by multiple bacteria species, showing varied skin appearance, including variable clinical signs and ectoparasitism/seborrheic conditions.
- Superficial pyoderma is often epidermis-restricted, not systemic, with a short duration and no scarring.
- Lesions include papules, transient pustules, crusts, intraepidermal or superficial folliculitis.
- Examples include impetigo (Staph. aureus), and dermatophilosis.
-
Deep Pyoderma:
- Involves deeper skin layers frequently associated with chronic courses, scarring, and systemic illness.
- Lesions include papules, pustules, subcutaneous nodules, abscesses, or ulcers.
- Histological changes may include deep folliculitis, nodular/diffuse suppurative or pyogranulomatous dermatitis.
- Examples include feline leprosy (Mycobacterium lepraemurium) and footrot (Fusobacterium necrophorum).
-
Canine Impetigo:
- A bacterial skin infection resulting in pustules and yellow crusty sores.
- Predisposed by moisture, abrasions, parasitism, and poor nutrition.
- Clinically manifested as superficial pustular dermatitis.
- Characterized by epidermal ulceration and inflammation, and likely neutrophil infiltration.
-
Dermatophilosis:
- Superficial exudative dermatitis, often seen in hot, humid climates (ruminants).
-
Feline Acne:
- Bacterial infection of hair follicles in telogen (resting phase).
- Characteristic lesions include acanthosis, inflammation, pustule formation, and comedo (obstructed follicle).
-
Canine Pyotraumatic Dermatitis:
- Secondary bacterial infection of self-traumatized skin.
- Characterized by intense pruritus, self-trauma, focal alopecia, excoriation, ulceration, and exudative lesions.
-
Swine Erysipelas:
- Presents as diamond-shaped erythematous plaques, characteristic of the infection.
-
Salmonellosis/Endotoxemias:
- Venous infarction of extremities is a common sign, due to endotoxin-induced venous thrombosis.
-
Mycotic Diseases (5.3):
- Superficial mycoses: growth restricted to keratinized tissue (e.g., dermatophytosis/ringworm).
- Dermatophytosis: the fungus (like _Microsporum spp._and Trichophyton spp.) doesn't invade living tissues, but colonies localized on keratinized skin structures, causing lesions including alopecia, scaling, papules, pustules, and sometimes furunculosis/crusting.
- Deep Mycoses: characterized by the organisms spreading into subcutaneous layers (e.g. Cryptococcus species).
-
Sporotrichosis:
- A subcutaneous mycosis presenting as skin and cutaneous tissue lesions, forming single/multiple nodules, which ulcerate and discharge thick red-brown exudate. Often heals slowly and deeply.
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Description
Test your knowledge on viral skin infections, including characteristics and histological features of various lesions. This quiz covers topics such as poxviral infections, contagious ecthyma, and neoplastic lesions. Perfect for students and professionals in the field of dermatology and infectious diseases.