Podcast
Questions and Answers
Which of the following is a sulfonylurea from the first generation?
Which of the following is a sulfonylurea from the first generation?
What is an example of a meglitinide?
What is an example of a meglitinide?
Which class of drugs includes Semaglutide?
Which class of drugs includes Semaglutide?
Which of the following is a Dipeptidyl Peptidase-4 inhibitor?
Which of the following is a Dipeptidyl Peptidase-4 inhibitor?
Signup and view all the answers
Which of the following is an example of an Alpha Glucosidase Inhibitor?
Which of the following is an example of an Alpha Glucosidase Inhibitor?
Signup and view all the answers
Study Notes
Insulin Secretion Stimulants
-
Sulfonylureas: Medications that promote insulin release from the pancreas.
-
1st Generation:
- Chlorpropamide: Long-acting sulfonylurea; risk of hypoglycemia.
- Tolbutamide: Shorter duration, lower risk of hypoglycemia than chlorpropamide.
-
2nd Generation:
- Glipizide: More potent than 1st generation; minimal side effects.
- Glyburide: More effective for long-term use; associated with weight gain.
-
1st Generation:
-
Meglitinides: Fast-acting insulin secretagogues.
- Nateglinide: Short duration; effective post meal.
- Repaglinide: Similar mechanism; crucial for managing blood glucose spikes after meals.
GLP-1 Analogues
- Exenatide: Mimics incretin hormones; enhances insulin secretion in response to meals.
- Liraglutide: Long-acting; supports weight loss and improves glycemic control.
- Semaglutide: Reduces appetite; found effective for type 2 diabetes management.
Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
- Linagliptin: No dose adjustment needed for renal impairment; generally well-tolerated.
- Saxagliptin: Effective; risk of heart failure in certain patients.
- Sitagliptin: Widely used; often prescribed in combination therapies.
Sodium - Glucose Co-Transporter 2 (SGLT2) Inhibitors
- Canagliflozin: Decreases renal glucose reabsorption; potential cardiovascular benefits.
- Dapagliflozin: Renal protective; associated with weight loss.
- Empagliflozin: Has cardiovascular and renal protection properties; aids in weight reduction.
Alpha-Glucosidase Inhibitors
- Acarbose: Slows carbohydrate absorption in the intestine; may cause gastrointestinal side effects.
- Miglitol: Similar action to acarbose; helps lower postprandial blood glucose levels.
Amylin Analogues
- Pramlintide: Complement to insulin therapy; helps control post-meal blood sugar levels and promotes satiety.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge on the various classes of insulin secretion stimulants including Sulfonylureas, Meglitinides, GLP-1 Analogues, DPP-4 inhibitors, and more. This quiz covers both first-generation and second-generation medications as well as their mechanisms and examples. Challenge yourself to identify key details and enhance your understanding of these important diabetes medications.
