Innate Immunity Quiz
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Questions and Answers

Which molecules are induced on the surface of the local blood vessel endothelium and on the infiltrating cells?

  • Selectins, integrins, ICAM/ImmG (correct)
  • Phagocytosis, adhesion, migration
  • Antibodies, antigens, lymphocytes
  • Cytokines, chemokines, complement

What is the first step in the process of recruitment of cells to the site of infection?

  • Reversible adherence (correct)
  • Production of cytokines
  • Migration under the influence of chemokines
  • Extravasion/diapedesis

What appears on the endothelial cell surface within minutes of exposure to inflammatory mediators?

  • ICAM/ImmG
  • Integrins
  • P-selectin (correct)
  • Complement

What enables the engulfing of bacteria and the recruitment of cells to the site of infection?

<p>Phagocytosis, cytokines, chemokines, activation of complement (C)</p> Signup and view all the answers

Which molecules are involved in the activation of E-selectin transcription and expression on cell surface?

<p>C5a and TNFa (D)</p> Signup and view all the answers

Which molecules bind to ICAM1&2 on endothelium and trigger a conformational change on the rolling cell?

<p>LFA-1 and CR3 (A)</p> Signup and view all the answers

Which molecule is expressed at junctions of endothelial cells and allows cells to squeeze through these junctions?

<p>CD31 (D)</p> Signup and view all the answers

What is the role of chemokines in the migration of cells through tissue to the infection?

<p>Increase adherence to endothelial cells (D)</p> Signup and view all the answers

Which proteins are induced by IL-1/IL-6/TNF during the acute phase response?

<p>Acute phase proteins (D)</p> Signup and view all the answers

What is the function of C reactive protein during the acute phase response?

<p>Opsonizes pathogens and triggers complement cascade (A)</p> Signup and view all the answers

What is the main function of mannose binding lectin during the acute phase response?

<p>Opsonizes pathogens (D)</p> Signup and view all the answers

Which process enables the engulfing of bacteria and the recruitment of cells to the site of infection?

<p>Phagocytosis (C)</p> Signup and view all the answers

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