Innate Immunity Quiz

Phagocytic cells recognize pathogens through ______ receptor

TLR4 recognizes ______ (LPS)

Innate immunity provides first line of defence at ______ surfaces

[Blank] proteins A & D found in lung fluid – they bind to and coat the surfaces of pathogens for phagocytosis by macrophages

Activation of TLRs triggers the production of ______, chemokines and the expression of co-stimulatory molecules

Phagocytosis is the process of engulfing and digesting ______

______ is directly toxic to the pathogen

______ is a characteristic of components of pathogens at some stage of infection

TLR4 recognizes ______ (LPS)

Innate immunity lacks ______ but can distinguish between self and non-self

______ proteins A & D found in lung fluid – they bind to and coat the surfaces of pathogens for phagocytosis by macrophages

Phagocytic cells recognize pathogens through ______ receptor

TLR4 recognizes ______ (LPS)

Innate immunity provides first line of defence at ______ surfaces

Innate immunity lacks ______ but can distinguish between self and non-self

Pattern recognition receptors are clonally distributed like in adaptive immunity

Surfactant proteins A & D found in lung fluid bind to and coat the surfaces of pathogens for phagocytosis by macrophages

Phagocytosis involves the internalization of pathogens in a membrane-bound vesicle called a phagosome

Innate immunity lacks specificity but can distinguish between self and non-self as it recognizes patterns that are common to pathogens

TLR4 recognizes lipopolysaccharide (LPS) - a cell wall component of gram-negative bacteria

Phagocytosis is the process of engulfing and digesting pathogens

Mucosal surfaces and external epithelia are not part of the front line of host defense in innate immunity

Deficiency in the process of mucous expulsion is evident in cystic fibrosis

Pattern recognition receptors are clonally distributed like in adaptive immunity

Phospholipase A is not secreted in tears and saliva

Innate immunity always causes clinical disease when pathogens get through epithelial barriers.

Mucosal surfaces secrete mucus which contains glycoproteins called mucins.

Deficiency in the process of expelling pathogens in the flow of mucus is evident in cystic fibrosis.

Lysozyme and phospholipase A are secreted in tears and saliva.

Innate immune mechanisms function only in the underlying tissue to prevent the establishment of infection.