Innate Immunity Quiz

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Which molecule recognises certain glycoproteins on cells such as sulfated-sialyl-Lewisx?

Histamine

LPS

C5a (correct)

TNFa

Which molecules are involved in the adherence of cells to the vessel wall, allowing them to roll along the wall?

Chemokines

ICAM1&2

E-selectin

Integrins LFA-1 and CR3 (correct)

Which molecule is expressed at junctions of endothelial cells and allows cells to squeeze through these junctions?

CR3

CD31 (correct)

E-selectin

LFA-1

Which molecules are involved in the migration of cells through tissue to the infection site under the influence of chemokines?

Chemokines and integrins Signup and view all the answers

Which cytokines induce hepatocytes in the liver to synthesise acute phase proteins?

IL-1/IL-6/TNF Signup and view all the answers

Which protein binds to the phosphocholine portion of certain bacterial and fungal cell-wall lipopolysaccharide?

C reactive protein Signup and view all the answers

Which molecules are involved in the activation of complement cascade?

C reactive protein and mannose binding lectin Signup and view all the answers

Which molecules are involved in the recognition of bacteria through pattern recognition receptors?

Adhesion molecules Signup and view all the answers

Which cells are involved in lymphocyte development and antigen recognition?

T cells Signup and view all the answers

Which molecule is a pathogen recognition molecule that opsonizes pathogens and triggers the complement cascade?

Mannose binding lectin Signup and view all the answers

Which cells are involved in the engulfing of bacteria and the recruitment of cells to the site of infection?

Macrophages Signup and view all the answers

Which molecules are involved in the activation of the acute phase response?

Cytokines produced by macrophages Signup and view all the answers

Which molecules are induced on the surface of the local blood vessel endothelium and on the infiltrating cells?

Selectins, integrins, ICAM/ImmG Signup and view all the answers

What appears on the endothelial cell surface within minutes of exposure to inflammatory mediators?

P-selectin Signup and view all the answers

What enables the engulfing of bacteria and the recruitment of cells to the site of infection?

Phagocytosis, cytokines, chemokines, complement, adhesion molecules Signup and view all the answers

What is the first step in the process of recruitment of cells to the site of infection?

Reversible adherence Signup and view all the answers

What mediates the recruitment of cells to the site of infection?

Chemokines and cell-adhesion molecules Signup and view all the answers

What is induced on the surface of infiltrating cells and the local blood vessel endothelium?

Cell-adhesion molecules Signup and view all the answers

What family of molecules enables the first step of reversible adherence during the recruitment of cells to the site of infection?

Selectins Signup and view all the answers

What appears on the endothelial cell surface within minutes of exposure to inflammatory mediators?

P-selectin Signup and view all the answers

What type of adherence is enabled by selectins during the recruitment of cells to the site of infection?

Reversible Signup and view all the answers

What is the final step in the process of recruitment of cells to the site of infection?

Migration under the influence of chemokines Signup and view all the answers

What enables the cells to come out of the center of the blood vessel and interact with the endothelium at inflammatory sites?

Dilated vessels and slower blood flow Signup and view all the answers

Innate Immunity Quiz

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Questions and Answers

Which molecule recognises certain glycoproteins on cells such as sulfated-sialyl-Lewisx?

Which molecules are involved in the adherence of cells to the vessel wall, allowing them to roll along the wall?

Which molecule is expressed at junctions of endothelial cells and allows cells to squeeze through these junctions?

Which molecules are involved in the migration of cells through tissue to the infection site under the influence of chemokines?

Which cytokines induce hepatocytes in the liver to synthesise acute phase proteins?

Which protein binds to the phosphocholine portion of certain bacterial and fungal cell-wall lipopolysaccharide?

Which molecules are involved in the activation of complement cascade?

Which molecules are involved in the recognition of bacteria through pattern recognition receptors?

Which cells are involved in lymphocyte development and antigen recognition?

Which molecule is a pathogen recognition molecule that opsonizes pathogens and triggers the complement cascade?

Which cells are involved in the engulfing of bacteria and the recruitment of cells to the site of infection?

Which molecules are involved in the activation of the acute phase response?

Which molecules are induced on the surface of the local blood vessel endothelium and on the infiltrating cells?

What appears on the endothelial cell surface within minutes of exposure to inflammatory mediators?

What enables the engulfing of bacteria and the recruitment of cells to the site of infection?

What is the first step in the process of recruitment of cells to the site of infection?

What mediates the recruitment of cells to the site of infection?

What is induced on the surface of infiltrating cells and the local blood vessel endothelium?

What family of molecules enables the first step of reversible adherence during the recruitment of cells to the site of infection?

What appears on the endothelial cell surface within minutes of exposure to inflammatory mediators?

What type of adherence is enabled by selectins during the recruitment of cells to the site of infection?

What is the final step in the process of recruitment of cells to the site of infection?

What enables the cells to come out of the center of the blood vessel and interact with the endothelium at inflammatory sites?

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