Innate Immunity Quiz
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Questions and Answers

Which complement protein forms pores in bacterial membranes to damage certain bacteria?

  • Factor H
  • Factor 1
  • C3b (correct)
  • DAF
  • Which protein mediates the ingestion of complement-tagged pathogens by phagocytes?

  • Factor H
  • CR1 (correct)
  • C5a
  • CD55
  • Which small complement fragment is needed to activate C2 on B cells?

  • Factor H
  • Factor 1
  • C3b
  • C5a (correct)
  • What do cytokines mainly induce through binding specific receptors?

    <p>Vasodilation</p> Signup and view all the answers

    Which cells do chemokines mainly function as chemoattractants for?

    <p>Monocyte/macrophage and neutrophils</p> Signup and view all the answers

    What is the function of chemokines in nearby responsive cells?

    <p>Chemotaxis</p> Signup and view all the answers

    Which cells do chemokines guide in adaptive immunity?

    <p>Lymphocytes</p> Signup and view all the answers

    What is the main function of chemokines in innate immunity?

    <p>Chemotaxis</p> Signup and view all the answers

    What induces responses through binding specific receptors on target cells?

    <p>Cytokines</p> Signup and view all the answers

    Which proteins are lacking on pathogen surfaces, allowing C3 to work?

    <p>Factor H and DAF</p> Signup and view all the answers

    What do the terminal complement proteins polymerize to form, which can kill certain pathogens?

    <p>Membrane attack complex (MAC)</p> Signup and view all the answers

    Which family of cytokines includes growth hormones and many interleukins?

    <p>Hematopoietin</p> Signup and view all the answers

    What is the main function of the complement system?

    <p>To mark pathogens for destruction by phagocytes</p> Signup and view all the answers

    How are complement proteins activated at sites of infection?

    <p>They are activated locally and trigger a series of inflammatory events</p> Signup and view all the answers

    What is the role of complement proteins in phagocytosis?

    <p>They opsonize pathogens for phagocytosis</p> Signup and view all the answers

    How is the complement system activated?

    <p>Through a triggered-enzyme cascade</p> Signup and view all the answers

    What happens to complement proteins at the start of the pathway?

    <p>A small number of complement proteins are activated, which is hugely amplified by each successive reaction</p> Signup and view all the answers

    What is the main role of the small fragments of some complement proteins?

    <p>Act as chemoattractants to recruit more phagocytes to the site and to activate these phagocytes</p> Signup and view all the answers

    What triggers the activation of complement proteins at sites of infection?

    <p>Local activation of complement proteins</p> Signup and view all the answers

    What is the function of opsonization in the immune response?

    <p>To make pathogens more susceptible to phagocytosis</p> Signup and view all the answers

    What is the primary outcome of complement protein activation?

    <p>Marking pathogens for destruction by phagocytes</p> Signup and view all the answers

    How are complement proteins distributed throughout the body?

    <p>Widely distributed throughout body fluids and tissues without effect</p> Signup and view all the answers

    What triggers the amplification of complement response?

    <p>Successive reaction of complement proteins</p> Signup and view all the answers

    How are complement proteins regulated?

    <p>Very tightly regulated</p> Signup and view all the answers

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