Innate Immunity Quiz
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Questions and Answers

Which complement protein forms pores in bacterial membranes to damage certain bacteria?

  • Factor H
  • Factor 1
  • C3b (correct)
  • DAF

Which protein mediates the ingestion of complement-tagged pathogens by phagocytes?

  • Factor H
  • CR1 (correct)
  • C5a
  • CD55

Which small complement fragment is needed to activate C2 on B cells?

  • Factor H
  • Factor 1
  • C3b
  • C5a (correct)

What do cytokines mainly induce through binding specific receptors?

<p>Vasodilation (C)</p> Signup and view all the answers

Which cells do chemokines mainly function as chemoattractants for?

<p>Monocyte/macrophage and neutrophils (A)</p> Signup and view all the answers

What is the function of chemokines in nearby responsive cells?

<p>Chemotaxis (D)</p> Signup and view all the answers

Which cells do chemokines guide in adaptive immunity?

<p>Lymphocytes (B)</p> Signup and view all the answers

What is the main function of chemokines in innate immunity?

<p>Chemotaxis (D)</p> Signup and view all the answers

What induces responses through binding specific receptors on target cells?

<p>Cytokines (B)</p> Signup and view all the answers

Which proteins are lacking on pathogen surfaces, allowing C3 to work?

<p>Factor H and DAF (A)</p> Signup and view all the answers

What do the terminal complement proteins polymerize to form, which can kill certain pathogens?

<p>Membrane attack complex (MAC) (B)</p> Signup and view all the answers

Which family of cytokines includes growth hormones and many interleukins?

<p>Hematopoietin (C)</p> Signup and view all the answers

What is the main function of the complement system?

<p>To mark pathogens for destruction by phagocytes (C)</p> Signup and view all the answers

How are complement proteins activated at sites of infection?

<p>They are activated locally and trigger a series of inflammatory events (D)</p> Signup and view all the answers

What is the role of complement proteins in phagocytosis?

<p>They opsonize pathogens for phagocytosis (B)</p> Signup and view all the answers

How is the complement system activated?

<p>Through a triggered-enzyme cascade (C)</p> Signup and view all the answers

What happens to complement proteins at the start of the pathway?

<p>A small number of complement proteins are activated, which is hugely amplified by each successive reaction (A)</p> Signup and view all the answers

What is the main role of the small fragments of some complement proteins?

<p>Act as chemoattractants to recruit more phagocytes to the site and to activate these phagocytes (A)</p> Signup and view all the answers

What triggers the activation of complement proteins at sites of infection?

<p>Local activation of complement proteins (D)</p> Signup and view all the answers

What is the function of opsonization in the immune response?

<p>To make pathogens more susceptible to phagocytosis (B)</p> Signup and view all the answers

What is the primary outcome of complement protein activation?

<p>Marking pathogens for destruction by phagocytes (A)</p> Signup and view all the answers

How are complement proteins distributed throughout the body?

<p>Widely distributed throughout body fluids and tissues without effect (B)</p> Signup and view all the answers

What triggers the amplification of complement response?

<p>Successive reaction of complement proteins (C)</p> Signup and view all the answers

How are complement proteins regulated?

<p>Very tightly regulated (C)</p> Signup and view all the answers

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