Initiator tRNA and Protein Synthesis Quiz
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Questions and Answers

Which tRNA is used as the initiator tRNA in protein synthesis?

  • A tRNA that recognizes the start codon
  • The same tRNA used to add methionine elsewhere in the protein (correct)
  • A tRNA that recognizes the stop codon
  • A different tRNA carrying a different amino acid

Where is the initiator tRNA added in the ribosome?

  • The E-site
  • The A-site
  • The P-site (correct)
  • The large subunit

What are eukaryotic initiator factors (eIFs)?

  • Proteins that aid in the elongation phase of protein synthesis
  • Proteins that recognize the stop codon
  • Proteins that recognize the 3' region of mRNA
  • Proteins that aid in the initiation phase of protein synthesis (correct)

Which region of the mRNA do eukaryotic initiator factors (eIFs) recognize?

<p>5' region of mRNA (A)</p> Signup and view all the answers

When do eukaryotic initiator factors (eIFs) dissociate from the small subunit of the ribosome?

<p>Before the small subunit assembles with the large subunit (A)</p> Signup and view all the answers

Where is the initiator tRNA added in the ribosome?

<p>P-site (D)</p> Signup and view all the answers

Which of the following statements is true about the termination of translation?

<p>Release factors bind to a ribosome with a stop codon in the A site. (A)</p> Signup and view all the answers

What is the role of release factors in translation termination?

<p>They bind to a ribosome with a stop codon in the A site. (B)</p> Signup and view all the answers

What happens when peptidyl transferase in the ribosome catalyzes the addition of H2O to peptidyl-tRNA?

<p>The growing polypeptide chain is freed from tRNA. (A)</p> Signup and view all the answers

Which of the following is true about ribosomes in eukaryotic cells?

<p>Eukaryotic cells can have more than 1 million ribosomes in them (A)</p> Signup and view all the answers

How many ribosomes can proceed along the length of a mRNA at any time?

<p>More than 1 million ribosomes (B)</p> Signup and view all the answers

Which one of these is true about ribosomes in eukaryotic cells?

<p>Eukaryotic cells can have more than 1 million ribosomes in them (B)</p> Signup and view all the answers

Which one of these is true about the differences between RNA and DNA sugars?

<p>RNA is made up of ribonucleotides while DNA is made up of deoxyribonucleotides (D)</p> Signup and view all the answers

Which one of these is true about the bases found in both RNA and DNA?

<p>Both RNA and DNA contain Guanine, Adenine, and Cytosine (C)</p> Signup and view all the answers

Which one of these is true about the base pairing in DNA?

<p>In DNA, Adenine forms base pair with Thymine (B)</p> Signup and view all the answers

Which enzyme forms phosphodiester bonds between neighboring nucleotides in RNA synthesis?

<p>RNA polymerase (B)</p> Signup and view all the answers

What is the direction of DNA transcription by RNA polymerase?

<p>5'→3' (A)</p> Signup and view all the answers

What are the substrates used by RNA polymerase during transcription?

<p>Ribonucleoside triphosphates (B)</p> Signup and view all the answers

Which enzyme is more accurate in synthesizing nucleic acids?

<p>DNA polymerase (D)</p> Signup and view all the answers

What is the role of RNA polymerase in transcription?

<p>Linking ribonucleotides (B)</p> Signup and view all the answers

How does RNA polymerase initiate an RNA chain?

<p>Without the need for a primer (C)</p> Signup and view all the answers

Which type of cells have RNA polymerase II that transcribes genes encoding for proteins?

<p>Eukaryotic cells (B)</p> Signup and view all the answers

What does RNA polymerase II transcribe in eukaryotic cells?

<p>mRNA (D)</p> Signup and view all the answers

What is the main difference between the transcription process in prokaryotic cells and eukaryotic cells?

<p>The presence of introns and exons (C)</p> Signup and view all the answers

Which of the following is a function of general transcription factors in transcription?

<p>Help RNA polymerase attach to the promoter region of DNA (A)</p> Signup and view all the answers

Which proteins are required by RNA polymerase II to facilitate transcription?

<p>General transcription factors (B)</p> Signup and view all the answers

Which type of mutation results in the addition or deletion of a single amino acid?

<p>Point mutation (C)</p> Signup and view all the answers

Which component of translation is responsible for matching tRNA molecules to codons in mRNA?

<p>Aminoacyl-tRNA synthetases (B)</p> Signup and view all the answers

Which position of the codon-anticodon pairing is the wobble position?

<p>Third position (D)</p> Signup and view all the answers

What is the role of aminoacyl-tRNA synthetases in translation?

<p>To attach amino acids to tRNA molecules (D)</p> Signup and view all the answers

Which of the following is true about the TATA box in eukaryotic promoters?

<p>It is a DNA sequence primarily composed of T and A (C)</p> Signup and view all the answers

Which of the following is true about RNA splicing?

<p>It is performed by spliceosomes, which are large complexes of proteins and RNA (C)</p> Signup and view all the answers

What is the role of the poly-A tail in mRNA?

<p>It stabilizes mRNA and facilitates its exit from the nucleus (B)</p> Signup and view all the answers

Which of the following is true about the genetic code?

<p>The start codon sets the correct reading frame (A)</p> Signup and view all the answers

Which of the following is true about the TATA box in eukaryotic promoters?

<p>The TATA box is a DNA sequence primarily composed of T and A. (A)</p> Signup and view all the answers

What is the role of transcriptional activators/repressors in gene expression?

<p>They bind to specific DNA sequences to increase or decrease expression of specific genes. (D)</p> Signup and view all the answers

Which of the following is true about RNA splicing?

<p>RNA splicing is performed by spliceosomes. (A)</p> Signup and view all the answers

What is the role of the poly-A tail in mRNA?

<p>The poly-A tail stabilizes mRNA. (D)</p> Signup and view all the answers

Which of the following is true about frame shift mutations?

<p>Frame shift mutations alter the reading frame by adding or deleting 1 or 2 nucleotides. (D)</p> Signup and view all the answers

Which of the following is true about point mutations?

<p>Missense mutations alter the nucleotide and result in the translation of the same amino acid. (C)</p> Signup and view all the answers

What is the role of tRNA in translation?

<p>tRNA carries amino acids to the ribosomes. (D)</p> Signup and view all the answers

What is the function of ribosomes in translation?

<p>Ribosomes catalyze the formation of peptide bonds. (C)</p> Signup and view all the answers

Which of the following is true about the TATA box in eukaryotic promoters?

<p>The TATA box is primarily composed of T and A nucleotides (A)</p> Signup and view all the answers

Which of the following is true about RNA splicing?

<p>RNA splicing is regulated by spliceosomes (B)</p> Signup and view all the answers

What is the role of the poly-A tail in mRNA?

<p>The poly-A tail stabilizes mRNA and prevents degradation (C)</p> Signup and view all the answers

Which of the following is true about the genetic code?

<p>The genetic code is non-redundant and each codon codes for a unique amino acid (D)</p> Signup and view all the answers

Which of the following is true about frame shift mutations?

<p>Frame shift mutations alter the reading frame by adding or deleting a single nucleotide. (D)</p> Signup and view all the answers

Which of the following is true about point mutations?

<p>Point mutations alter the reading frame by altering a single nucleotide. (B)</p> Signup and view all the answers

Which of the following is true about tRNA?

<p>tRNA binds to codons on mRNA using its anti-codon. (C)</p> Signup and view all the answers

Which of the following is true about ribosomes?

<p>Ribosomes are composed of ribosomal RNA and ribosomal proteins. (A)</p> Signup and view all the answers

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