Caspase Activation in Apoptosis Quiz
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Questions and Answers

What triggers the assembly of adaptor proteins carrying multiple binding sites for the caspase amino-terminal domain?

  • DNA replication signals
  • Apoptotic signals (correct)
  • Cell proliferation signals
  • Cell differentiation signals

    • What happens to the initiator caspases upon binding to the adaptor proteins?

  • They become inactive
  • They dissociate from the adaptor proteins
  • They dimerize and are activated (correct)
  • They undergo conformational changes

    • What happens to the executioner caspases upon cleavage at a site in the protease domain by an initiator caspase?

  • They undergo an activating conformational change (correct)
  • They bind to DNA
  • They dissociate from the cell
  • They become inactive

    • What happens to the protease domain of the initiator caspases after activation?

    <p>It is rearranged into a large and small subunit</p> Signup and view all the answers

    What is the initial form of executioner caspases?

    <p>Inactive dimers</p> Signup and view all the answers

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