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Inherited Forms of Cancer - Genetics Quiz

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Inherited Forms of Cancer - Genetics Quiz

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Questions and Answers

What type of genes are oncogenes?

Recessive-acting inhibitory genes

Dominant-acting stimulatory genes (correct)

Genes that regulate telomerase

Genes that control the cycle of cell division

Which of the following statements about proto-oncogenes is true?

They are responsible for basic cellular functions in normal cells. (correct)

They promote abnormal cell growth.

They are mutated recessive-acting inhibitory genes.

They are expressed abnormally in cancer cells.

When do tumor-suppressor genes become inactive?

When they cause abnormal cell growth

When they gain a new function

When they lose heterozygosity (correct)

When they are expressed in a different cell type

What is the effect of gain-of-function mutations in oncogenes?

They promote abnormal cell growth Signup and view all the answers

Which type of mutation results in the encoded protein being expressed in a cell type where it is not normally expressed?

Gain-of-function mutation Signup and view all the answers

What is the primary function of proto-oncogenes in normal cells?

Promote normal cellular functions Signup and view all the answers

How do oncogenes differ from proto-oncogenes?

Oncogenes have gain-of-function mutations. Signup and view all the answers

What effect do tumor-suppressor genes have on cell division when they are mutated?

They promote abnormal cell growth Signup and view all the answers

What is the primary effect of loss of heterozygosity in tumor-suppressor genes?

Inactivation of the tumor-suppressor gene Signup and view all the answers

Which of the following best describes the role of DNA-repair genes in cancer?

Maintaining genomic stability and preventing mutations Signup and view all the answers