Inhalational General Anesthetic Agents
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Questions and Answers

What is the primary reason why chloroform fell out of favor?

  • Its tendency to cause asphyxia when used alone
  • Cardiac arrhythmias, respiratory depression, and hepatotoxicity (correct)
  • Its high cost
  • Its low potency
  • Which of the following anesthetics is associated with dose-related nephrotoxicity?

  • Enflurane
  • Methoxyflurane (correct)
  • Isoflurane
  • Halothane
  • What is the term for the lack of oxygen and blood flow to the brain?

  • Hypoxia
  • Hypotension
  • Asphyxia (correct)
  • Anoxia
  • Which anesthetic is still commonly used in practice today?

    <p>Nitrous oxide</p> Signup and view all the answers

    Which anesthetic is associated with evidence of seizure activity on EEG?

    <p>Enflurane</p> Signup and view all the answers

    What does the Minimum Alveolar Concentration (MAC) of an anaesthetic vapour represent?

    <p>The concentration that prevents movement in 50% of subjects to a surgical stimulus</p> Signup and view all the answers

    Which anaesthetic vapour requires a higher concentration to be effective due to its poorly lipophilic nature?

    <p>Nitrous oxide</p> Signup and view all the answers

    What effect does this anaesthetic have on renal function?

    <p>Decreases renal blood flow, glomerular filtration rate, and urinary output</p> Signup and view all the answers

    What is a pharmacokinetic advantage of Sevoflurane?

    <p>It induces a faster induction and recovery time</p> Signup and view all the answers

    What effect does this anaesthetic have on neuromuscular function?

    <p>Induces adequate to good muscle relaxation</p> Signup and view all the answers

    In which type of surgery is this anaesthetic commonly used?

    <p>Cardiac and Neurosurgery</p> Signup and view all the answers

    What is the primary site of action for anesthetic agents that produce immobility?

    <p>Spinal cord</p> Signup and view all the answers

    Which of the following is a desirable property of an ideal anesthetic agent?

    <p>Easy titrateability</p> Signup and view all the answers

    What is the term for the loss of all sensations, including pain, sleep, and amnesia?

    <p>Anesthesia</p> Signup and view all the answers

    Which receptors are thought to be enhanced by anesthetic agents?

    <p>GABAA and glycine receptors</p> Signup and view all the answers

    What is the definition of anesthesia?

    <p>A reversible loss of all sensations and consciousness</p> Signup and view all the answers

    What is the current understanding of the mechanism of action of general anesthetics?

    <p>Not precisely known</p> Signup and view all the answers

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