17 Questions
What is the primary reason why chloroform fell out of favor?
Cardiac arrhythmias, respiratory depression, and hepatotoxicity
Which of the following anesthetics is associated with dose-related nephrotoxicity?
Methoxyflurane
What is the term for the lack of oxygen and blood flow to the brain?
Asphyxia
Which anesthetic is still commonly used in practice today?
Nitrous oxide
Which anesthetic is associated with evidence of seizure activity on EEG?
Enflurane
What does the Minimum Alveolar Concentration (MAC) of an anaesthetic vapour represent?
The concentration that prevents movement in 50% of subjects to a surgical stimulus
Which anaesthetic vapour requires a higher concentration to be effective due to its poorly lipophilic nature?
Nitrous oxide
What effect does this anaesthetic have on renal function?
Decreases renal blood flow, glomerular filtration rate, and urinary output
What is a pharmacokinetic advantage of Sevoflurane?
It induces a faster induction and recovery time
What effect does this anaesthetic have on neuromuscular function?
Induces adequate to good muscle relaxation
In which type of surgery is this anaesthetic commonly used?
Cardiac and Neurosurgery
What is the primary site of action for anesthetic agents that produce immobility?
Spinal cord
Which of the following is a desirable property of an ideal anesthetic agent?
Easy titrateability
What is the term for the loss of all sensations, including pain, sleep, and amnesia?
Anesthesia
Which receptors are thought to be enhanced by anesthetic agents?
GABAA and glycine receptors
What is the definition of anesthesia?
A reversible loss of all sensations and consciousness
What is the current understanding of the mechanism of action of general anesthetics?
Not precisely known
This quiz covers the classification, pharmacology, and dosages of inhalational general anesthetic drugs, as well as their ideal properties and pharmacokinetic/pharmacodynamic parameters. It also touches on the history of inhalational anesthetics.
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