Inhalational General Anesthetic Agents

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Questions and Answers

What is the primary reason why chloroform fell out of favor?

  • Its tendency to cause asphyxia when used alone
  • Cardiac arrhythmias, respiratory depression, and hepatotoxicity (correct)
  • Its high cost
  • Its low potency

Which of the following anesthetics is associated with dose-related nephrotoxicity?

  • Enflurane
  • Methoxyflurane (correct)
  • Isoflurane
  • Halothane

What is the term for the lack of oxygen and blood flow to the brain?

  • Hypoxia
  • Hypotension
  • Asphyxia (correct)
  • Anoxia

Which anesthetic is still commonly used in practice today?

<p>Nitrous oxide (D)</p> Signup and view all the answers

Which anesthetic is associated with evidence of seizure activity on EEG?

<p>Enflurane (D)</p> Signup and view all the answers

What does the Minimum Alveolar Concentration (MAC) of an anaesthetic vapour represent?

<p>The concentration that prevents movement in 50% of subjects to a surgical stimulus (B)</p> Signup and view all the answers

Which anaesthetic vapour requires a higher concentration to be effective due to its poorly lipophilic nature?

<p>Nitrous oxide (A)</p> Signup and view all the answers

What effect does this anaesthetic have on renal function?

<p>Decreases renal blood flow, glomerular filtration rate, and urinary output (B)</p> Signup and view all the answers

What is a pharmacokinetic advantage of Sevoflurane?

<p>It induces a faster induction and recovery time (C)</p> Signup and view all the answers

What effect does this anaesthetic have on neuromuscular function?

<p>Induces adequate to good muscle relaxation (A)</p> Signup and view all the answers

In which type of surgery is this anaesthetic commonly used?

<p>Cardiac and Neurosurgery (A)</p> Signup and view all the answers

What is the primary site of action for anesthetic agents that produce immobility?

<p>Spinal cord (C)</p> Signup and view all the answers

Which of the following is a desirable property of an ideal anesthetic agent?

<p>Easy titrateability (A)</p> Signup and view all the answers

What is the term for the loss of all sensations, including pain, sleep, and amnesia?

<p>Anesthesia (D)</p> Signup and view all the answers

Which receptors are thought to be enhanced by anesthetic agents?

<p>GABAA and glycine receptors (B)</p> Signup and view all the answers

What is the definition of anesthesia?

<p>A reversible loss of all sensations and consciousness (D)</p> Signup and view all the answers

What is the current understanding of the mechanism of action of general anesthetics?

<p>Not precisely known (C)</p> Signup and view all the answers

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