Pharmacology: Blood-Brain Barrier & Anesthesia
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Questions and Answers

Which type of drugs can generally cross the blood-brain barrier due to their characteristics?

  • Ionic compounds
  • Highly charged molecules
  • Nonpolar, lipid soluble drugs (correct)
  • Polar drugs
  • What is the primary function of the blood-brain barrier?

  • To protect the CNS by limiting harmful substances (correct)
  • To facilitate the passage of all drugs into the brain
  • To ensure efficient neurotransmitter signaling
  • To enhance drug absorption in the brain
  • Which of the following is NOT categorized as an antimuscarinic drug for treating parkinsonism?

  • Procyclidine
  • Diazepam (correct)
  • Benztropine
  • Trihexyphenidyl
  • Benzodiazepines and nonbenzodiazepines are primarily used for what purpose?

    <p>To promote sleep and relaxation</p> Signup and view all the answers

    Which category of agents can induce general anesthesia at higher doses?

    <p>Barbiturates</p> Signup and view all the answers

    What is primarily involved in the control of motor activities?

    <p>Basal Ganglia</p> Signup and view all the answers

    Which part of the brain is responsible for regulating temperature control and appetite?

    <p>Hypothalamus</p> Signup and view all the answers

    What is the role of the cerebrum in CNS medications?

    <p>Affects cortical function indirectly</p> Signup and view all the answers

    Which disorders are associated with deficits in the basal ganglia?

    <p>Parkinson's Disease</p> Signup and view all the answers

    How do drugs used to treat epilepsy primarily function?

    <p>By modifying neuronal activity</p> Signup and view all the answers

    What kind of functions does the thalamus integrate?

    <p>Types of sensations and their relay</p> Signup and view all the answers

    Which statement correctly describes the action of antianxiety drugs?

    <p>They modify the activity of neurons to treat anxiety</p> Signup and view all the answers

    Which is NOT a function attributed to the hypothalamus?

    <p>Motor control</p> Signup and view all the answers

    What is the primary neurotransmitter activity involved in schizophrenia?

    <p>Increased Dopamine</p> Signup and view all the answers

    Which term refers to the split between thought, emotion, and behavior as described by Eugen Bleuler?

    <p>Schizophrenia</p> Signup and view all the answers

    Which of the following is NOT a fundamental symptom (4 A's) of schizophrenia?

    <p>Akathisia</p> Signup and view all the answers

    What class of drugs primarily help to manage symptoms of schizophrenia?

    <p>Antipsychotics</p> Signup and view all the answers

    What is a common side effect associated with traditional antipsychotics?

    <p>Extrapyramidal symptoms</p> Signup and view all the answers

    Which of the following is characterized by a strong urge to move about and restlessness?

    <p>Akathisia</p> Signup and view all the answers

    Which drug is a traditional antipsychotic with the trade name 'Haldol'?

    <p>Haloperidol</p> Signup and view all the answers

    What are the secondary symptoms of schizophrenia that include delusions and hallucinations called?

    <p>Secondary symptoms</p> Signup and view all the answers

    What is a primary adverse effect of phenobarbital?

    <p>Sedation</p> Signup and view all the answers

    Which drug is primarily used for acute treatment of status epilepticus?

    <p>Lorazepam</p> Signup and view all the answers

    Which of the following antiepileptic drugs is effective in treating generalized tonic-clonic seizures?

    <p>Fosphenytoin</p> Signup and view all the answers

    What mechanism do antiepileptic drugs typically utilize to treat seizures?

    <p>Alter ion movement across neuronal membranes</p> Signup and view all the answers

    Which adverse effect is especially associated with phenytoin?

    <p>Gingival hyperplasia</p> Signup and view all the answers

    Which classification of seizures is carbamazepine not effective in treating?

    <p>Absence seizures</p> Signup and view all the answers

    Which of the following are side effects associated with benzodiazepines like diazepam?

    <p>Paradoxical increase in seizures</p> Signup and view all the answers

    Which of the following adverse effects is common with antipsychotic medications?

    <p>Photosensitivity</p> Signup and view all the answers

    Which side effect is commonly associated with succinimides?

    <p>Skin rashes and itching</p> Signup and view all the answers

    What is the primary use of Valproic Acid?

    <p>Absence seizures and bipolar disorder</p> Signup and view all the answers

    What is the first-line treatment for Status Epilepticus?

    <p>Benzodiazepines</p> Signup and view all the answers

    Which of the following is NOT a common side effect of Valproic Acid?

    <p>Drowsiness</p> Signup and view all the answers

    In the treatment of absence seizures, which medication is primarily used?

    <p>Ethosuximide</p> Signup and view all the answers

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