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Inhalation Dosage Form
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Inhalation Dosage Form

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Questions and Answers

What is the recommended particle size for a therapeutic agent in inhalation dosage forms?

  • 20 um or less
  • 30 um or less
  • 5 um or less (correct)
  • 10 um or less
  • Which inhalation delivery system is typically used for the acute care of patients?

  • Dry powder inhalers
  • Ultrasonic nebulizers
  • Metered-dose inhalers
  • Nebulizers (correct)
  • What type of inhaler delivers the drug as powder to be inspired by the patient?

  • Metered-dose inhalers
  • Air jet nebulizers
  • Ultrasonic nebulizers
  • Dry powder inhalers (correct)
  • Which type of nebulizer forms ultrasound waves in the nebulizer chamber using a ceramic crystal?

    <p>Ultrasonic nebulizers</p> Signup and view all the answers

    What is the most frequent use of inhalation therapy mentioned in the text?

    <p>Treatment of asthma</p> Signup and view all the answers

    What is the main purpose of the metering valve in a metered-dose inhaler (MDI)?

    <p>To measure an accurate dose to the patient</p> Signup and view all the answers

    What is the fundamental requirement of a metered-dose inhaler (MDI) formulation?

    <p>Delivering the drug dose accurately and reproducibly</p> Signup and view all the answers

    Why are surfactants or dispersing agents typically included in metered-dose inhalers (MDIs)?

    <p>To maintain the disperse nature of the drug and provide lubrication for the metering valves</p> Signup and view all the answers

    What are hydrofluroalkane (HFC) propellants primarily used for in metered-dose inhalers (MDIs)?

    <p>Long-term use in MDIs</p> Signup and view all the answers

    What is the primary material used to make the actuator in a metered-dose inhaler (MDI)?

    <p>Plastic</p> Signup and view all the answers

    Study Notes

    Inhalation Dosage Forms

    • The recommended particle size for a therapeutic agent in inhalation dosage forms is 1-5 μm.

    Inhalation Delivery Systems

    • The pressurized metered-dose inhaler (pMDI) is typically used for the acute care of patients.

    Dry Powder Inhalers

    • Dry powder inhalers deliver the drug as powder to be inspired by the patient.

    Nebulizers

    • The ultrasonic nebulizer forms ultrasound waves in the nebulizer chamber using a ceramic crystal.

    Inhalation Therapy

    • The most frequent use of inhalation therapy is for the treatment of asthma and chronic obstructive pulmonary disease (COPD).

    Metered-Dose Inhalers (MDIs)

    • The main purpose of the metering valve in a metered-dose inhaler (MDI) is to control the amount of formulation released per dose.
    • The fundamental requirement of a metered-dose inhaler (MDI) formulation is that it must be able to be broken down into small particles that can be inhaled into the lungs.
    • Surfactants or dispersing agents are typically included in metered-dose inhalers (MDIs) to improve the stability and dispersion of the drug particles.
    • Hydrofluroalkane (HFC) propellants are primarily used in metered-dose inhalers (MDIs) to facilitate the dispersion of the drug particles.
    • The primary material used to make the actuator in a metered-dose inhaler (MDI) is plastic.

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    Description

    Test your knowledge of inhalation dosage forms and their applications in treating various diseases. Explore the use of ß-agonists, corticosteroids, anticholinergic agents, and inhaled insulin for systemic drug delivery. Understand the characteristics of particles used in inhalation therapy.

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