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Questions and Answers
What is the recommended particle size for a therapeutic agent in inhalation dosage forms?
Which inhalation delivery system is typically used for the acute care of patients?
What type of inhaler delivers the drug as powder to be inspired by the patient?
Which type of nebulizer forms ultrasound waves in the nebulizer chamber using a ceramic crystal?
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What is the most frequent use of inhalation therapy mentioned in the text?
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What is the main purpose of the metering valve in a metered-dose inhaler (MDI)?
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What is the fundamental requirement of a metered-dose inhaler (MDI) formulation?
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Why are surfactants or dispersing agents typically included in metered-dose inhalers (MDIs)?
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What are hydrofluroalkane (HFC) propellants primarily used for in metered-dose inhalers (MDIs)?
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What is the primary material used to make the actuator in a metered-dose inhaler (MDI)?
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Study Notes
Inhalation Dosage Forms
- The recommended particle size for a therapeutic agent in inhalation dosage forms is 1-5 μm.
Inhalation Delivery Systems
- The pressurized metered-dose inhaler (pMDI) is typically used for the acute care of patients.
Dry Powder Inhalers
- Dry powder inhalers deliver the drug as powder to be inspired by the patient.
Nebulizers
- The ultrasonic nebulizer forms ultrasound waves in the nebulizer chamber using a ceramic crystal.
Inhalation Therapy
- The most frequent use of inhalation therapy is for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Metered-Dose Inhalers (MDIs)
- The main purpose of the metering valve in a metered-dose inhaler (MDI) is to control the amount of formulation released per dose.
- The fundamental requirement of a metered-dose inhaler (MDI) formulation is that it must be able to be broken down into small particles that can be inhaled into the lungs.
- Surfactants or dispersing agents are typically included in metered-dose inhalers (MDIs) to improve the stability and dispersion of the drug particles.
- Hydrofluroalkane (HFC) propellants are primarily used in metered-dose inhalers (MDIs) to facilitate the dispersion of the drug particles.
- The primary material used to make the actuator in a metered-dose inhaler (MDI) is plastic.
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Description
Test your knowledge of inhalation dosage forms and their applications in treating various diseases. Explore the use of ß-agonists, corticosteroids, anticholinergic agents, and inhaled insulin for systemic drug delivery. Understand the characteristics of particles used in inhalation therapy.
