Inflammatory Response Quiz

Inflammatory Response

• Some local effects of inflammation include redness, warmth, and swelling.
• Prolonged glucocorticoid use can cause atrophy of lymphoid tissue, increased infection resistance, and decreased protein synthesis.
• Applying ice to an injury causes reduced edema by promoting vasoconstriction.
• Healing of extensive skin loss is most successful through the use of biosynthetic skin substitutes.
• Prostaglandins are produced from activated plasma proteins and increase capillary permeability.
• Neutrophils increase significantly in the blood during inflammation.

Inflammatory Response (continued)

• Abscesses contain purulent exudate.
• Nonspecific agents that protect cells from viruses are called interferons.
• Causes of inflammation include physical damage, allergic reactions, and infection.
• The net hydrostatic pressure in capillary exchange is based on the difference in hydrostatic pressures between capillaries and interstitial fluid.
• Cardinal signs of inflammation, excluding nausea, include redness, loss of function, and swelling.

Inflammatory Response (continued)

• Drugs with anti-inflammatory, analgesic, and antipyretic properties include COX-2 inhibitors (NSAIDs), glucocorticoids, ibuprofen, and acetaminophen.
• Aspirin (ASA) is discouraged in children with viral infections due to the risk of Reye's syndrome
• Systemic manifestations of inflammation include pyrexia (fever), malaise, and anorexia, but not local swelling.
• Phagocytosis is a crucial aspect of inflammation, performed by macrophages.

Healing and Inflammation

• Resolution occurs when minimal tissue damage allows for cell recovery.
• Regeneration involves the replacement of damaged cells by similar cells capable of mitosis.
• Granulation tissue forms a temporary fix for damaged tissue and not a permanent replacement.
• Scar tissue replaces damaged cells that are unable to mitosis.
• Incorrect statement: Inflammation caused by an allergen, burn, infection is a serous exudate, disorders with inflammation do not end in "-sarcoma".
• Inflammation helps localize/isolate foreign material with fibrinogen.
• Cold application reduces inflammation immediately following injury causes vasoconstriction.

Wound Healing and Burns

• Applying cold to a wound reduces inflammation by causing local vasoconstriction following injury.
• Tissue engineering research aims to create functional replacements for damaged tissue when regeneration isn't possible
• Causes of extensive burns are due to the high temperature, duration, and extent of the exposure.
• Inhalation-related injuries from burns include carbon monoxide absorption preventing sufficient oxygen uptake.
• Hypermetabolism, increased heat loss, recurrent stress response are all contributors to stress in burn victims.
• Scar tissue can cause obstructions by attaching to nearby normal tissue and shrinking over time.

Inflammation and Chemical Mediators

• Cytokines are chemical mediators that are released by macrophages.
• A substance not normally found in the blood, appearing in acute inflammation/necrosis, is C-reactive protein.
• Eosinophils are increased during allergic responses.
• COX-2 inhibitors are associated with an increased risk of heart attack.

Test your knowledge on the inflammatory response in the human body. This quiz covers local effects, mediators, and mechanisms of inflammation. Understand the role of cells and substances involved in the inflammatory process.