Podcast
Questions and Answers
What is the recommended treatment for Diff infection in ulcerative colitis patients?
What is the recommended treatment for Diff infection in ulcerative colitis patients?
- NSAIDs
- Broad spectrum antibiotics
- TPN
- PO vancomycin (correct)
Which of the following is NOT recommended in the management of ulcerative colitis?
Which of the following is NOT recommended in the management of ulcerative colitis?
- High-dose NSAIDs (correct)
- Nicotine therapy
- Probiotics
- Surgery
When is surgery likely indicated in ulcerative colitis?
When is surgery likely indicated in ulcerative colitis?
- Mild symptoms with short duration
- Responsive to medication therapy within 2 days
- Experiencing mild side effects from medication
- Severe colitis unresponsive to conventional therapy (correct)
What is an indication for cancer surveillance in ulcerative colitis patients?
What is an indication for cancer surveillance in ulcerative colitis patients?
Which of the following treatments has limited place in ulcerative colitis therapy according to the text?
Which of the following treatments has limited place in ulcerative colitis therapy according to the text?
What is the hypothesis regarding chronic intestinal inflammation?
What is the hypothesis regarding chronic intestinal inflammation?
Which adverse effect is associated with long-term use of Metronidazole?
Which adverse effect is associated with long-term use of Metronidazole?
What is the mechanism of action of Ciprofloxacin?
What is the mechanism of action of Ciprofloxacin?
Which of the following describes the mechanism of action of Thiopurines?
Which of the following describes the mechanism of action of Thiopurines?
What should be monitored when a patient is on Azathioprine or Mercaptopurine?
What should be monitored when a patient is on Azathioprine or Mercaptopurine?
Why is TPMT testing necessary before initiating Thiopurine therapy?
Why is TPMT testing necessary before initiating Thiopurine therapy?
What is the main difference between the step-up and top-down approach for treating inflammatory bowel disease (IBD)?
What is the main difference between the step-up and top-down approach for treating inflammatory bowel disease (IBD)?
Which medication for IBD is specifically mentioned to have therapeutic activity occurring throughout the entire gastrointestinal (GI) tract?
Which medication for IBD is specifically mentioned to have therapeutic activity occurring throughout the entire gastrointestinal (GI) tract?
What is a common symptom of mesalamine-based reactions when the dosage exceeds 3g/day?
What is a common symptom of mesalamine-based reactions when the dosage exceeds 3g/day?
Which medication used in IBD treatment is a dimer of two 5-ASA molecules?
Which medication used in IBD treatment is a dimer of two 5-ASA molecules?
What is the mechanism of action of corticosteroids in treating IBD?
What is the mechanism of action of corticosteroids in treating IBD?
Which form of budesonide has less systemic adverse effects compared to prednisone?
Which form of budesonide has less systemic adverse effects compared to prednisone?
What is the recommended treatment for mild-moderate Crohn's disease limited to the ileum and colon?
What is the recommended treatment for mild-moderate Crohn's disease limited to the ileum and colon?
How should Prednisone be tapered for moderate-severe Crohn's disease induction?
How should Prednisone be tapered for moderate-severe Crohn's disease induction?
What is the most appropriate next step in treatment if a patient with moderate-severe Crohn's disease does not respond to corticosteroids?
What is the most appropriate next step in treatment if a patient with moderate-severe Crohn's disease does not respond to corticosteroids?
What is the dosing range for Azathioprine when used without biologics?
What is the dosing range for Azathioprine when used without biologics?
Which of the following medications is NOT effective for moderate-severe Crohn's disease induction according to the guidelines?
Which of the following medications is NOT effective for moderate-severe Crohn's disease induction according to the guidelines?
What is the maximum duration of total steroid use recommended for tapering in moderate-severe Crohn's disease induction?
What is the maximum duration of total steroid use recommended for tapering in moderate-severe Crohn's disease induction?
What is the mechanism of action of Methotrexate as an immunomodulator?
What is the mechanism of action of Methotrexate as an immunomodulator?
Which adverse effect is associated with Methotrexate as an immunomodulator?
Which adverse effect is associated with Methotrexate as an immunomodulator?
Prior to initiating TNF-α inhibitors, what should be assessed for?
Prior to initiating TNF-α inhibitors, what should be assessed for?
Which vaccine should be given before initiating TNF-α inhibitors treatment?
Which vaccine should be given before initiating TNF-α inhibitors treatment?
What is a common clinical pearl related to monitoring patients on Infliximab?
What is a common clinical pearl related to monitoring patients on Infliximab?
Which TNF-α inhibitor is 100% humanized?
Which TNF-α inhibitor is 100% humanized?
What is the recommended maintenance dose interval for Adalimumab?
What is the recommended maintenance dose interval for Adalimumab?
Which type of treatment failure occurs if there is a low or undetectable trough level of TNF-α inhibitors with antibody development?
Which type of treatment failure occurs if there is a low or undetectable trough level of TNF-α inhibitors with antibody development?
What should be considered if there is inadequate response to TNF-α inhibitors due to inflammatory mediators not being blocked by the current therapy?
What should be considered if there is inadequate response to TNF-α inhibitors due to inflammatory mediators not being blocked by the current therapy?