Inflammation: Acute & Chronic
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Questions and Answers

What are the common manifestations of inflammation?

  • Numbness, tingling, weakness, and muscle atrophy
  • Nausea, vomiting, diarrhea, and abdominal pain
  • Fever, cough, fatigue, and headache
  • Redness, swelling, heat, pain, and loss of function (correct)
  • Which of the following is not a microbial agent that can cause inflammation?

  • Fungi
  • Bacteria
  • Viruses
  • Allergens (correct)
  • What is the consequence of viral infection on individual cells?

  • Cell mutation and transformation
  • Intracellular multiplication leading to cell death (correct)
  • Enhanced cellular metabolism
  • Increased cellular communication
  • How do bacteria contribute to inflammation?

    <p>Release of specific toxins - either exotoxins or endotoxins</p> Signup and view all the answers

    What can cause tissue damage and inflammation through direct contact or radiation?

    <p>Physical and chemical agents</p> Signup and view all the answers

    What is the function of fever in response to inflammation?

    <p>To improve the efficiency of leukocyte killing and impair the replication of some invading organisms</p> Signup and view all the answers

    What can lead to an acute inflammatory response?

    <p>Tissue necrosis</p> Signup and view all the answers

    What can cause a hypersensitivity reaction that damages tissues?

    <p>Bacterial toxins</p> Signup and view all the answers

    What can lead to further complications such as chronic inflammation and scarring?

    <p>Tissue damage from inflammation</p> Signup and view all the answers

    What can have both local and systemic effects, including fever, malaise, and leukocytosis?

    <p>Inflammation</p> Signup and view all the answers

    What causes cell death through multiplication inside cells or by inhibiting their function?

    <p>Bacterial toxins</p> Signup and view all the answers

    What are the vascular changes characterizing acute inflammation?

    <p>Vasodilation and increased vascular permeability</p> Signup and view all the answers

    Which of the following can trigger acute inflammation?

    <p>Tissue damage</p> Signup and view all the answers

    What can cause tissue necrosis and inflammation?

    <p>Bacterial infections</p> Signup and view all the answers

    What can also trigger acute inflammation?

    <p>Hypersensitivity reactions</p> Signup and view all the answers

    What can cause vascular leakage and contribute to inflammation?

    <p>Histamine and cytokines</p> Signup and view all the answers

    Which physical agents can cause tissue damage and vascular leakage?

    <p>Ischemia, trauma, and thermal injury</p> Signup and view all the answers

    What foreign bodies can trigger an inflammatory response?

    <p>Splinters, dirt, and sutures</p> Signup and view all the answers

    What does chronic inflammation result in?

    <p>Tissue destruction, repair, and fibrosis</p> Signup and view all the answers

    What can cause chronic inflammation?

    <p>Prolonged exposure to toxins</p> Signup and view all the answers

    In which diseases is chronic inflammation a common component?

    <p>Ulcers, tuberculosis, pulmonary silicosis</p> Signup and view all the answers

    When does chronic inflammation tend to occur?

    <p>Under certain conditions including persistent organisms</p> Signup and view all the answers

    Study Notes

    • Acute inflammation is characterized by vascular changes, including vasodilation and increased vascular permeability, leading to edema and white blood cell recruitment.
    • The stimuli for acute inflammation include infections, tissue damage, immune reactions, and chemical mediators.
    • Infections, such as bacterial, viral, fungal, parasitic, and microbial toxins, can cause tissue necrosis and inflammation.
    • Immune reactions, including hypersensitivity reactions, can also trigger acute inflammation.
    • Chemical mediators, such as histamine and cytokines, can cause vascular leakage and further contribute to inflammation.
    • Physical agents, like ischemia, trauma, and thermal injury, can cause tissue damage and vascular leakage.
    • Foreign bodies, like splinters, dirt, and sutures, can also trigger an inflammatory response.
    • In chronic inflammation, the inflammatory response persists for a long duration and results in tissue destruction, repair, and fibrosis.
    • Chronic inflammation can be caused by persistent injury or infection, prolonged exposure to toxins, and autoimmune diseases.
    • Chronic inflammation is a common component in many diseases, including ulcers, tuberculosis, pulmonary silicosis, and autoimmune diseases like rheumatoid arthritis, lupus erythematosus, and multiple sclerosis.
    • Chronic inflammation tends to occur under certain conditions, including persistent organisms, repeated bouts of acute inflammation, and prolonged exposure to toxins.

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    Description

    Learn about the response of living tissue to injury, including redness, swelling, heat, pain, and loss of function. Explore the causes of inflammation, including microbial infections and tissue injury.

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