Infectious Diseases and Laboratory Tests
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Questions and Answers

What laboratory test should be assigned to the patient suspected of having Crimean-Congo hemorrhagic fever?

  • Microscopy examination of blood
  • Bacteriological blood culture
  • PCR of nasopharyngeal swab
  • Enzyme-linked immunosorbent assay (correct)
  • What specific complication may develop in a patient with hemorrhagic fever with renal syndrome?

  • Acute kidney injury (correct)
  • Edema of the brain
  • Septic shock
  • Pneumonia
  • What is the likely type of helminth causing abdominal pain, fever, and previous symptoms like weakness and headache in a student from Yemen?

  • schistosomiasis (correct)
  • teniosis
  • ascariasis
  • enterobiosis
  • Which symptom is least likely to be associated with Crimean-Congo hemorrhagic fever?

    <p>Hemoptysis</p> Signup and view all the answers

    Which helminth matches the description of having a segmented body, a length of 2 m, and a head with 4 suction cups and hooks in two rows?

    <p>Taenia solium</p> Signup and view all the answers

    What condition is likely indicated by a thickening with a bubble at the end under the skin after consuming untreated water in Yemen?

    <p>Dracunculosis</p> Signup and view all the answers

    What symptom found in the 27-year-old patient indicates the development of advanced hemorrhagic fever with renal syndrome?

    <p>Hemorrhagic rash</p> Signup and view all the answers

    What is the primary epidemiological concern in diagnosing Crimean-Congo hemorrhagic fever?

    <p>Recent tick bites</p> Signup and view all the answers

    Which factor is not considered an epidemiological criterion for diagnosing opisthorchiasis?

    <p>Presence of pets such as cats or dogs</p> Signup and view all the answers

    What would be the most appropriate laboratory research method for a child who expelled a 15 cm cyanotic white worm along with gastrointestinal symptoms?

    <p>Fecal examination for eggs</p> Signup and view all the answers

    What is a characteristic clinical manifestation of the acute phase of opisthorchiasis?

    <p>Dyspeptic phenomena</p> Signup and view all the answers

    How did the woman with fascioliasis most likely get infected?

    <p>Ate unwashed strawberries</p> Signup and view all the answers

    Which of the following scenarios is most consistent with the complications of hemorrhagic fever with renal syndrome?

    <p>Patient developing vomiting with blood after onset of renal failure</p> Signup and view all the answers

    What is NOT a typical presenting symptom of Crimean-Congo hemorrhagic fever?

    <p>Abdominal pain on the left side</p> Signup and view all the answers

    What is the minimum age contraindicated for the use of praziquantel in children?

    <p>Up to 4 years</p> Signup and view all the answers

    Which helminth is associated with larvae detected in blood smears stained according to Romanovsky in a student from Africa?

    <p>Filariasis</p> Signup and view all the answers

    What is the diagnosis for white helminths measuring 5-10 mm with a bubble-like expansion of the esophagus found in feces?

    <p>Enterobiosis</p> Signup and view all the answers

    Which type of parasitic infection involves the detection of trematodes in the gallbladder and large ducts of the liver?

    <p>Fasciolosis</p> Signup and view all the answers

    In the context of tick-borne diseases, which of the following is most critical for identifying Crimean-Congo hemorrhagic fever in a patient?

    <p>Documentation of symptoms following tick exposure</p> Signup and view all the answers

    What type of infection is most likely if a patient presents with cases of opisthorchiasis in a locality by a river?

    <p>Clonorchiasis</p> Signup and view all the answers

    How long does it typically take for a tsetse fly to develop the invasive stage in the body of a trypanosome?

    <p>20 days</p> Signup and view all the answers

    What is a factor that would not allow transmission of trypanosomiasis from a tsetse fly bite?

    <p>Prompt preventive vaccinations</p> Signup and view all the answers

    Which characteristic is NOT typical for Taenia solium?

    <p>Causes schistosomiasis</p> Signup and view all the answers

    Which condition is characterized by specific symptoms associated with the consumption of contaminated food or water?

    <p>Dracunculosis</p> Signup and view all the answers

    Which virus is associated with a more severe disease upon subsequent infection with a heterologous strain?

    <p>Dengue virus</p> Signup and view all the answers

    What is the likely reservoir host for the enveloped, (-) ssRNA filamentous virus in a patient presenting with maculopapular rash?

    <p>Bats</p> Signup and view all the answers

    In a case of infection with an enveloped, segmented (-) ssRNA virus, what is the reservoir host suspected?

    <p>Rats</p> Signup and view all the answers

    What is currently considered the best option for preventing future outbreaks of Ebola?

    <p>Rebuild scientific infrastructure</p> Signup and view all the answers

    What is identified as the biggest risk factor for infection with Ebola?

    <p>Nursing a patient at home</p> Signup and view all the answers

    Which diagnostic method is specifically used for detecting dengue?

    <p>All of the above</p> Signup and view all the answers

    What clinical symptoms were present in the patient returning from Liberia with suspected infection?

    <p>Mucosal bleeding and conjunctival injection</p> Signup and view all the answers

    What type of virus is the dengue virus classified as?

    <p>Single-stranded RNA virus</p> Signup and view all the answers

    What type of organism causes intestinal amoebiasis?

    <p>Protozoa</p> Signup and view all the answers

    When does Dracunculiasis typically manifest?

    <p>Immediately after infection</p> Signup and view all the answers

    Which symptom is NOT associated with chronic fascioliasis?

    <p>Intestinal obstruction</p> Signup and view all the answers

    What is the most common extra-intestinal complication of amoebiasis?

    <p>Amoebic liver abscess</p> Signup and view all the answers

    Which laboratory method is most reliable for diagnosing yellow fever?

    <p>Virus isolation from the patient’s blood</p> Signup and view all the answers

    Which characteristic is NOT true about the etiology of yellow fever?

    <p>It is stable under extreme temperatures</p> Signup and view all the answers

    Which vector is involved in the transmission of Dracunculiasis?

    <p>Freshwater crustacean</p> Signup and view all the answers

    What is the primary mode of infection for intestinal amoebiasis?

    <p>Fecal-oral transmission</p> Signup and view all the answers

    In fascioliasis, after how many weeks do fascioles reach the bile ducts?

    <p>7 weeks</p> Signup and view all the answers

    Which statement regarding malaria is incorrect?

    <p>Distant relapses are possible in three-day malaria</p> Signup and view all the answers

    Erythrocyte schizogony lasting 72 hours is characteristic of which type of malaria?

    <p>Four-day malaria</p> Signup and view all the answers

    Which is not a characteristic symptom of yellow fever?

    <p>Abdominal pain</p> Signup and view all the answers

    Which disease is characterized by ulcers with undercut edges in the colon?

    <p>Intestinal amoebiasis</p> Signup and view all the answers

    Which larva can be collected from peripheral blood at midnight?

    <p>Filarial larva</p> Signup and view all the answers

    What is the most common site for extra-intestinal amebiasis abscesses?

    <p>Liver</p> Signup and view all the answers

    Which laboratory test is primarily used for the detection of pathogens in cases of suspected amoebiasis?

    <p>Microscopy of stool</p> Signup and view all the answers

    Given the symptoms of cramping abdominal pain, bloody diarrhea, and high mucus content, what is the most likely diagnosis for a patient with these characteristics?

    <p>Amoebiasis</p> Signup and view all the answers

    In a patient presenting with hallucinations and hyperemic mucous membranes, what is the most relevant diagnosis?

    <p>Epidemic Typhus</p> Signup and view all the answers

    What common symptom is associated with amoebiasis, which distinguishes it from other gastrointestinal infections?

    <p>Raspberry jelly-like stools</p> Signup and view all the answers

    For a patient diagnosed with amebiasis, which treatment is commonly administered?

    <p>Metronidazole</p> Signup and view all the answers

    In relation to abdominal findings, which area is typically tender in cases of amoebiasis?

    <p>Blind and ascending intestines</p> Signup and view all the answers

    What general condition is suggested by the clinical findings of hepatosplenomegaly and tachycardia in a 72-year-old patient?

    <p>Infection</p> Signup and view all the answers

    Study Notes

    Case Studies

    • Case 185 (№=200097): A 40-year-old man with 9 years of antiretroviral therapy adherence presented with intermittent fever for a month. Splenomegaly and hepatomegaly (spleen enlarged 7 cm below left costal margin, liver enlarged 6 cm below right costal margin) were observed. Spleen aspiration revealed leishmaniasis. The patient's CD4 count was 54 cells/μL, despite an undetectable viral load.
    • Case 184 (№=200096): A 35-year-old patient was admitted with a serious condition. Symptoms included vomiting, abdominal pain, back pain, pale face, and nosebleeds. Hemorrhagic fever with renal syndrome was diagnosed. The time of illness was specified as oliguric.
    • Case 183 (№=200095): Relevant laboratory data in a patient with hemorrhagic fever with renal syndrome is presented. Key findings include moderate leukocytosis (primarily due to elevated stab and segmented neutrophils), increased ESR, elevated protein in urine (1.32 g/L), presence of squamous epithelium (10-15 per high-power field), leukocytes (2-3 per high-power field), fresh erythrocytes (30-40 per high-power field), and elevated creatinine (280 μmol/L) and urea (19 mmol/L). The period of the disease is oliguric.
    • Case 182 (№=200094): A 36-year-old patient with hemorrhagic fever with renal syndrome and acute kidney injury. The symptoms include headache, back pain, anorexia, pale skin, dry mouth, facial swelling, nosebleeding, vomiting with blood, hemorrhagic rash, blood pressure of 150/100, bradycardia, and anuria. Urinalysis reveals anuria. Tests including complete blood count with elevated ESR, anemia, leukopenia, and thrombocytopenia are noted. A protein level test is recommended for the patient.

    Additional Information

    • Different Diseases: The document also contains information about other diseases (e.g., anthrax, brucellosis, Q-fever, tick-borne encephalitis, visceral brucellosis, Crimean-Congo hemorrhagic fever) and their associated signs or symptoms.
    • Laboratory findings: Laboratory findings, including blood counts, urine analysis (specific gravity, protein, squamous and fresh erythrocytes, leukocytes), and biochemical parameters (creatinine, urea) are frequently mentioned, especially during the diagnosis of specific illnesses.
    • Period of illness: The descriptions often indicate the specific clinical phase or period (prodromal, oliguric, polyuric, convalescence) associated with the disease in the patient case reports.
    • Causative Organisms and Vectors: The potential causative microorganisms, modes of transmission, and relevant vectors are mentioned. Information about ticks, mosquitoes, and other vectors is included for several diseases.
    • Medical History: Medical history, symptoms, and epidemiological information provide context for possible causes and diagnoses of the presented cases. Infections often involve traveling, bites, and contact with animals. Eating raw fish and tick bites are examples of possible exposure routes.

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    Description

    This quiz covers various aspects of infectious diseases, focusing on laboratory tests for conditions like Crimean-Congo hemorrhagic fever and hemorrhagic fever with renal syndrome. It also explores symptoms and helminths associated with specific regions such as Yemen. Test your knowledge on diagnosing and understanding these severe diseases.

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