Immunology Workbook
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Questions and Answers

Which immunoglobulin is most commonly found in blood and tissue fluid?

  • IgM
  • IgE
  • IgD
  • IgG (correct)
  • Which immunoglobulin is primarily associated with allergic reactions?

  • IgM
  • IgA
  • IgD
  • IgE (correct)
  • What is the primary role of IgD antibodies on B lymphocyte membranes?

  • Serving as antigen-specific receptors (correct)
  • Defending against pathogens
  • Activating the complement system
  • Transporting immune cells
  • Which immunoglobulin serves as the earliest antibody response in a primary immune response?

    <p>IgM</p> Signup and view all the answers

    How is maternal IgG provided to newborns?

    <p>Crossing the placenta</p> Signup and view all the answers

    What is the relationship between phagocytes and pathogens?

    <p>Phagocytes engulf and destroy pathogens</p> Signup and view all the answers

    Which statement about IgE is true?

    <p>IgE is typically found in high levels in asthmatics.</p> Signup and view all the answers

    What are the toxic materials found in the phagolysosome that kill pathogens?

    <p>Antimicrobial agents and enzymes</p> Signup and view all the answers

    What is defined as microscopic organisms that may be beneficial or pathogenic?

    <p>Microbes</p> Signup and view all the answers

    Which substance is specifically capable of eliciting an immune response?

    <p>Antigen</p> Signup and view all the answers

    What role do antibodies primarily play in the immune system?

    <p>Killing or weakening pathogens</p> Signup and view all the answers

    Which type of cytokine is produced by Th1 T-helper cells?

    <p>Type-1 cytokines</p> Signup and view all the answers

    Which immunoglobulin is found in the respiratory tract and digestive system?

    <p>IgA</p> Signup and view all the answers

    Cytokines produced by Th2 T-helper cells are classified as what type?

    <p>Type-2 cytokines</p> Signup and view all the answers

    What can antibodies activate in the presence of lysosome?

    <p>Complement system</p> Signup and view all the answers

    Which of the following is NOT a type of cytokine?

    <p>Microbes</p> Signup and view all the answers

    What is the primary role of antigen-presenting cells in the immune system?

    <p>They activate immature T cells.</p> Signup and view all the answers

    Where are antigen-presenting cells primarily found in the body?

    <p>In nodes and spleen.</p> Signup and view all the answers

    Which of the following best describes the process of stimulating B cells by antigen-presenting cells?

    <p>It promotes B cell growth and differentiation.</p> Signup and view all the answers

    What function do the messengers mentioned in the context of adaptive immunity serve?

    <p>They regulate the immune response.</p> Signup and view all the answers

    What triggers the adaptive immune response according to the information provided?

    <p>Cell surface receptors on antigen-presenting cells.</p> Signup and view all the answers

    Which statement correctly describes the role of immunology?

    <p>Immunology is the study of the body's defense systems and responses.</p> Signup and view all the answers

    What is a key characteristic of non-specific (innate) immunity?

    <p>It is the body's first line of defense against infections.</p> Signup and view all the answers

    Which of the following components is part of the adaptive (acquired) immune system?

    <p>Helper T cells</p> Signup and view all the answers

    Which of the following correctly differentiates between non-specific and adaptive immunity?

    <p>Non-specific immunity acts broadly while adaptive immunity targets specific pathogens.</p> Signup and view all the answers

    Which is not considered a cell of the non-specific immune system?

    <p>B cells</p> Signup and view all the answers

    What method is recommended for note-taking during the immunology sessions?

    <p>Creating memory maps or spider diagrams.</p> Signup and view all the answers

    Which of the following is an outcome for students after the immunology session?

    <p>Ability to identify organs of the immune system.</p> Signup and view all the answers

    What is the intended duration to read the article on antibody-mediated vs. cell-mediated immunity?

    <p>10 minutes</p> Signup and view all the answers

    What type of proteins are involved in promoting phagocytosis of bacteria?

    <p>Opsonins</p> Signup and view all the answers

    Which process involves cells ingesting or engulfing other cells or particles?

    <p>Phagocytosis</p> Signup and view all the answers

    What is the role of antigen presenting cells?

    <p>To process protein antigens into peptides</p> Signup and view all the answers

    What is apoptosis commonly referred to as?

    <p>Programmed cell death</p> Signup and view all the answers

    What component of the immune system plays a significant role in host defense and inflammation?

    <p>Complement system</p> Signup and view all the answers

    Which of the following pathways is NOT part of the complement system activation?

    <p>Fibronectin pathway</p> Signup and view all the answers

    What is the primary function of opsonins in the immune system?

    <p>To coat antigens for easier recognition</p> Signup and view all the answers

    Which type of immune cell is involved in phagocytosis?

    <p>Neutrophils</p> Signup and view all the answers

    What do mast cells secrete in response to hypersensitivity reactions?

    <p>Histamine</p> Signup and view all the answers

    Where are mast cells derived from?

    <p>Bone marrow</p> Signup and view all the answers

    What triggers the release of histamine by mast cells?

    <p>Antibodies</p> Signup and view all the answers

    What is the primary function of dendritic cells in the immune system?

    <p>Linking innate and adaptive immunity</p> Signup and view all the answers

    What type of immune response do mast cells contribute to?

    <p>Innate immune response</p> Signup and view all the answers

    What type of cell are mast cells classified as?

    <p>Granulocyte</p> Signup and view all the answers

    What is the characteristic content of the granules in mast cells?

    <p>Histamine and heparin</p> Signup and view all the answers

    What differentiates mast cells from other immune cells?

    <p>Location of maturation</p> Signup and view all the answers

    Study Notes

    Immunology Workbook

    • This workbook is used alongside immunology sessions
    • Students complete tasks independently
    • Follow PowerPoint slides' instructions
    • Use various note-taking methods, spider diagrams, pictures, tables, to create comprehensive immunology notes
    • Preparation for the next session aims to consolidate knowledge
    • Learning outcomes for the session: define immunology, identify the terminology, describe the body's natural defenses, identify non-specific and adaptive immune systems' components/functions, distinguish between these, and locate immune system cells

    Introduction

    • Workbook's purpose: support immunology sessions.
    • First session focuses on introduction to immunology, self-directed learning.
    • Work through each slide, complete required activities.
    • Resources include documents and research articles for further knowledge.
    • Employ various note-taking methods (spider diagrams/pictures/tables) for effective information organization.
    • Complete notes are vital for next session learning consolidation.
    • Learning outcomes: define immunology, describe natural defenses, identify components/functions of non/adaptive immunity, differentiate between non/adaptive, locate immune system cells

    Antibody-Mediated vs. Cell-Mediated Immunity

    • Read article up to section 10 of 14
    • Duration: 15 minutes

    Immune System Organs/Tissues

    • Research and create own notes, spider diagram or memory map on immune system organs/tissues
    • Duration: 15 minutes
    • Reference provided resources for immune system organs information.

    Worksheet 1: Immunology Terminology

    • Notate and review new terminology as encountered
    • Use provided resources to support learning, research if needed

    Microbes, Antigens, Cytokines, Antibodies

    • Describe microbes, antigens, cytokines, and antibodies, along with examples.
    • Highlight different types of antibodies (IgA, IgD, IgE, IgG, IgM) and their functions.
    • Differentiate between the non-specific (innate) and adaptive (acquired) immunity.

    Phagocytes, Proteins, and Immune responses

    • Describe how phagocytes work and engulf pathogens.
    • Explain the role of proteins, such as antibodies and cytokines, in the immune system.
    • Describe the different types of immunity, innate and adaptive immunity, highlighting the characteristics of each.
    • Define opsonins and their role in phagocytosis.
    • Identify immune system protein types, antibodies, signaling proteins, complement proteins.
    • Detail IgG and IgM responses.

    Opsonins

    • Define opsonins.
    • Explain the role of substances in serum that promote phagocytosis of bacteria. (e.g. IgG antibody, C3b molecule).

    Phagocytosis

    • Define phagocytosis, describing the process by which certain cells ingest or engulf other cells or particles.

    Apoptosis

    • Explain apoptosis as a type of programmed cell death for unwanted or abnormal cells

    Antigen-Presenting Cells

    • Describe antigen-presenting cells' role in processing and presenting protein antigens in ways recognized by T-cell receptors on the cell's surface.

    Complement System

    • Explain the role of the complement system in the immune system response, including its function in host defense and inflammation.

    Cells of the Immune System

    • Describe the different types of cells (e.g., neutrophils, macrophages, eosinophils, basophils, mast cells, dendritic cells) in the innate immune system and their functions.
    • Describe the roles of specific cells in the adaptive immune system.

    Innate vs. Adaptive Immunity

    • Summarize the differences between innate and adaptive immunity in terms of specificity, time response, antigen dependence, and memory responses.

    Immune System Barriers

    • Describe the anatomical and physiological barriers of the innate immune system.
    • Provide examples of barriers in the oral cavity, such as the skin, mucous membranes, and temperature regulation.
    • Mention the role of chemical mediators for defense.
    • Provide specific examples of barriers present in the oral cavity, such as low pH and enzymes.
    • Discuss inflammation, including phagocytic cells' actions and cytokine release.
    • Identify chemokines and histamine roles in attracting immune cells to infection sites.

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