Immunology Quiz: Lymphoid Cells and Adaptive Immune System
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Questions and Answers

Which type of cells recognize peptide Major Histocompatibility Complex (pMHC) Class II complexes?

  • Ts cells
  • NK cells
  • Th cells (correct)
  • Tc cells

Where do mature B cells express IgM and IgD surface immunoglobulins?

  • Bone marrow (correct)
  • Spleen
  • Thymus
  • Lymph nodes

Which type of cells differentiate into plasma cells upon stimulation?

  • B cells (correct)
  • Ts cells
  • Tc cells
  • NK cells

What do Natural Killer (NK) cells lack on their surface?

<p>T cell &amp; B cell surface markers (C)</p> Signup and view all the answers

Which type of lymphocytes are key players in the adaptive immune response and participate in regulating other cells?

<p>Th cells (D)</p> Signup and view all the answers

Where do T-cells migrate from in order to mature and develop T-cell receptors (TCRs)?

<p>Bone marrow (D)</p> Signup and view all the answers

Which lymphocytes are restricted to recognition of peptide Major Histocompatibility Complex (pMHC) Class I complexes?

<p>Tc cells (B)</p> Signup and view all the answers

What is a characteristic feature of plasma cells?

<p>Synthesize and display Ig of only one antibody specificity on their surface (B)</p> Signup and view all the answers

Which of the following statements about B cell education in the bone marrow is correct?

<p>Self-reactive B cells undergo apoptosis to prevent autoimmunity. (D)</p> Signup and view all the answers

What is the primary function of secondary lymphoid tissues and organs?

<p>Allowing cellular interactions and exposure to antigens. (C)</p> Signup and view all the answers

Which of the following statements about the spleen is incorrect?

<p>The spleen is responsible for T cell education. (A)</p> Signup and view all the answers

What changes in red blood cell (RBC) morphology would be observed in peripheral blood after spleen rupture or splenectomy (spleen removal)?

<p>Presence of spherocytes (spherical RBCs). (B)</p> Signup and view all the answers

Which of the following statements about lymph nodes is correct?

<p>Lymph nodes are located along the lymphatic vessels. (A)</p> Signup and view all the answers

Which of the following is the largest secondary lymphoid organ?

<p>Spleen (C)</p> Signup and view all the answers

What is the role of the cortex and medulla in lymph nodes?

<p>Both the cortex and medulla are sites for initiating immune responses. (C)</p> Signup and view all the answers

Which of the following statements about the lymphatic system is correct?

<p>Lymphatic vessels transport lymph fluid away from tissues and organs. (B)</p> Signup and view all the answers

Which of the following statements about mucosa-associated lymphoid tissue (MALT) is correct?

<p>MALT includes structures like tonsils and Peyer's patches. (B)</p> Signup and view all the answers

What is the primary function of lymph nodes?

<p>Filtering lymph and initiating immune responses. (D)</p> Signup and view all the answers

Which of the following statements about T cell receptor (TCR) and B cell receptor (BCR) development is correct?

<p>They develop in the bone marrow (A)</p> Signup and view all the answers

Which of the following statements about natural killer (NK) cells and natural killer T (NKT) cells is incorrect?

<p>They develop in the bone marrow (B)</p> Signup and view all the answers

What is the primary function of killer-activating receptors (KARs) on NK and NKT cells?

<p>To recognize and bind to stress molecules on virally-infected or malignant host cells (A)</p> Signup and view all the answers

Which of the following statements about primary lymphoid organs is incorrect?

<p>They are where immune cells interact and encounter antigens (C)</p> Signup and view all the answers

What is the primary function of the thymus in T cell development?

<p>To educate T cells to distinguish self from non-self antigens (D)</p> Signup and view all the answers

Which of the following statements about positive selection in the thymus is correct?

<p>It ensures that T cells can recognize self MHC molecules (B)</p> Signup and view all the answers

What is the purpose of negative selection in the thymus?

<p>To eliminate T cells that can strongly recognize self-antigens (A)</p> Signup and view all the answers

Which of the following statements about secondary (peripheral) lymphoid organs is correct?

<p>They are sites where immune cells interact, encounter antigens, and respond to threats (C)</p> Signup and view all the answers

Which of the following is a characteristic of mature T cells that have successfully completed the selection processes in the thymus?

<p>They express either CD4 or CD8 molecules, but not both (B)</p> Signup and view all the answers

The text compares the selection processes in the thymus to the training of which elite military group?

<p>Marine Corps (B)</p> Signup and view all the answers

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