Immunology Quiz: Lymphoid Cells and Adaptive Immune System

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Which type of cells recognize peptide Major Histocompatibility Complex (pMHC) Class II complexes?

Ts cells

NK cells

Th cells (correct)

Tc cells

Where do mature B cells express IgM and IgD surface immunoglobulins?

Bone marrow (correct)

Spleen

Thymus

Lymph nodes

Which type of cells differentiate into plasma cells upon stimulation?

B cells (correct)

Ts cells

Tc cells

NK cells

What do Natural Killer (NK) cells lack on their surface?

T cell & B cell surface markers (C) Signup and view all the answers

Which type of lymphocytes are key players in the adaptive immune response and participate in regulating other cells?

Th cells (D) Signup and view all the answers

Where do T-cells migrate from in order to mature and develop T-cell receptors (TCRs)?

Bone marrow (D) Signup and view all the answers

Which lymphocytes are restricted to recognition of peptide Major Histocompatibility Complex (pMHC) Class I complexes?

Tc cells (B) Signup and view all the answers

What is a characteristic feature of plasma cells?

Synthesize and display Ig of only one antibody specificity on their surface (B) Signup and view all the answers

Which of the following statements about B cell education in the bone marrow is correct?

Self-reactive B cells undergo apoptosis to prevent autoimmunity. (D) Signup and view all the answers

What is the primary function of secondary lymphoid tissues and organs?

Allowing cellular interactions and exposure to antigens. (C) Signup and view all the answers

Which of the following statements about the spleen is incorrect?

The spleen is responsible for T cell education. (A) Signup and view all the answers

What changes in red blood cell (RBC) morphology would be observed in peripheral blood after spleen rupture or splenectomy (spleen removal)?

Presence of spherocytes (spherical RBCs). (B) Signup and view all the answers

Which of the following statements about lymph nodes is correct?

Lymph nodes are located along the lymphatic vessels. (A) Signup and view all the answers

Which of the following is the largest secondary lymphoid organ?

Spleen (C) Signup and view all the answers

What is the role of the cortex and medulla in lymph nodes?

Both the cortex and medulla are sites for initiating immune responses. (C) Signup and view all the answers

Which of the following statements about the lymphatic system is correct?

Lymphatic vessels transport lymph fluid away from tissues and organs. (B) Signup and view all the answers

Which of the following statements about mucosa-associated lymphoid tissue (MALT) is correct?

MALT includes structures like tonsils and Peyer's patches. (B) Signup and view all the answers

What is the primary function of lymph nodes?

Filtering lymph and initiating immune responses. (D) Signup and view all the answers

Which of the following statements about T cell receptor (TCR) and B cell receptor (BCR) development is correct?

They develop in the bone marrow (A) Signup and view all the answers

Which of the following statements about natural killer (NK) cells and natural killer T (NKT) cells is incorrect?

They develop in the bone marrow (B) Signup and view all the answers

What is the primary function of killer-activating receptors (KARs) on NK and NKT cells?

To recognize and bind to stress molecules on virally-infected or malignant host cells (A) Signup and view all the answers

Which of the following statements about primary lymphoid organs is incorrect?

They are where immune cells interact and encounter antigens (C) Signup and view all the answers

What is the primary function of the thymus in T cell development?

To educate T cells to distinguish self from non-self antigens (D) Signup and view all the answers

Which of the following statements about positive selection in the thymus is correct?

It ensures that T cells can recognize self MHC molecules (B) Signup and view all the answers

What is the purpose of negative selection in the thymus?

To eliminate T cells that can strongly recognize self-antigens (A) Signup and view all the answers

Which of the following statements about secondary (peripheral) lymphoid organs is correct?

They are sites where immune cells interact, encounter antigens, and respond to threats (C) Signup and view all the answers

Which of the following is a characteristic of mature T cells that have successfully completed the selection processes in the thymus?

They express either CD4 or CD8 molecules, but not both (B) Signup and view all the answers

The text compares the selection processes in the thymus to the training of which elite military group?

Marine Corps (B) Signup and view all the answers