Immunology Quiz: Lymphoid Cells and Adaptive Immune System
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Questions and Answers

Which type of cells recognize peptide Major Histocompatibility Complex (pMHC) Class II complexes?

  • Ts cells
  • NK cells
  • Th cells (correct)
  • Tc cells

    • Where do mature B cells express IgM and IgD surface immunoglobulins?

  • Bone marrow (correct)
  • Spleen
  • Thymus
  • Lymph nodes

    • Which type of cells differentiate into plasma cells upon stimulation?

  • B cells (correct)
  • Ts cells
  • Tc cells
  • NK cells

    • What do Natural Killer (NK) cells lack on their surface?

    <p>T cell &amp; B cell surface markers</p> Signup and view all the answers

    Which type of lymphocytes are key players in the adaptive immune response and participate in regulating other cells?

    <p>Th cells</p> Signup and view all the answers

    Where do T-cells migrate from in order to mature and develop T-cell receptors (TCRs)?

    <p>Bone marrow</p> Signup and view all the answers

    Which lymphocytes are restricted to recognition of peptide Major Histocompatibility Complex (pMHC) Class I complexes?

    <p>Tc cells</p> Signup and view all the answers

    What is a characteristic feature of plasma cells?

    <p>Synthesize and display Ig of only one antibody specificity on their surface</p> Signup and view all the answers

    Which of the following statements about B cell education in the bone marrow is correct?

    <p>Self-reactive B cells undergo apoptosis to prevent autoimmunity.</p> Signup and view all the answers

    What is the primary function of secondary lymphoid tissues and organs?

    <p>Allowing cellular interactions and exposure to antigens.</p> Signup and view all the answers

    Which of the following statements about the spleen is incorrect?

    <p>The spleen is responsible for T cell education.</p> Signup and view all the answers

    What changes in red blood cell (RBC) morphology would be observed in peripheral blood after spleen rupture or splenectomy (spleen removal)?

    <p>Presence of spherocytes (spherical RBCs).</p> Signup and view all the answers

    Which of the following statements about lymph nodes is correct?

    <p>Lymph nodes are located along the lymphatic vessels.</p> Signup and view all the answers

    Which of the following is the largest secondary lymphoid organ?

    <p>Spleen</p> Signup and view all the answers

    What is the role of the cortex and medulla in lymph nodes?

    <p>Both the cortex and medulla are sites for initiating immune responses.</p> Signup and view all the answers

    Which of the following statements about the lymphatic system is correct?

    <p>Lymphatic vessels transport lymph fluid away from tissues and organs.</p> Signup and view all the answers

    Which of the following statements about mucosa-associated lymphoid tissue (MALT) is correct?

    <p>MALT includes structures like tonsils and Peyer's patches.</p> Signup and view all the answers

    What is the primary function of lymph nodes?

    <p>Filtering lymph and initiating immune responses.</p> Signup and view all the answers

    Which of the following statements about T cell receptor (TCR) and B cell receptor (BCR) development is correct?

    <p>They develop in the bone marrow</p> Signup and view all the answers

    Which of the following statements about natural killer (NK) cells and natural killer T (NKT) cells is incorrect?

    <p>They develop in the bone marrow</p> Signup and view all the answers

    What is the primary function of killer-activating receptors (KARs) on NK and NKT cells?

    <p>To recognize and bind to stress molecules on virally-infected or malignant host cells</p> Signup and view all the answers

    Which of the following statements about primary lymphoid organs is incorrect?

    <p>They are where immune cells interact and encounter antigens</p> Signup and view all the answers

    What is the primary function of the thymus in T cell development?

    <p>To educate T cells to distinguish self from non-self antigens</p> Signup and view all the answers

    Which of the following statements about positive selection in the thymus is correct?

    <p>It ensures that T cells can recognize self MHC molecules</p> Signup and view all the answers

    What is the purpose of negative selection in the thymus?

    <p>To eliminate T cells that can strongly recognize self-antigens</p> Signup and view all the answers

    Which of the following statements about secondary (peripheral) lymphoid organs is correct?

    <p>They are sites where immune cells interact, encounter antigens, and respond to threats</p> Signup and view all the answers

    Which of the following is a characteristic of mature T cells that have successfully completed the selection processes in the thymus?

    <p>They express either CD4 or CD8 molecules, but not both</p> Signup and view all the answers

    The text compares the selection processes in the thymus to the training of which elite military group?

    <p>Marine Corps</p> Signup and view all the answers

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