9 Questions
Which cytokine directs the migration of leukocytes through the body?
IFN family
Which family of cytokines prevent virally infected cells from replicating and from making new viral particles?
IFN family
Endogenous antigen could bind to ____ to stimulate ____ T cells.
MHCH, CD8+
Exogenous antigen could bind to ____ to stimulate ____ T cells.
MHC-1, CD8+
Transplantation antigen is:
HLA
CD means:
Cluster of differentiation
The CD molecule also named HIV receptor is:
CD4
Ankylosing spondylitis is associated with:
HLA A27
The term 'MHC restriction' refers to the:
Requirement for antigen to be recognized in association with MHC molecules
Study Notes
Cytokines and Immunology
- IFN (Interferon) family of cytokines prevents virally infected cells from replicating and making new viral particles.
- Chemokines direct the migration of leukocytes through the body.
Antigen Presentation
- Exogenous antigen binds to MHC-1 to stimulate CD8+ T cells.
- Endogenous antigen binds to MHC-1 to stimulate CD8+ T cells.
- MHC-II binds to CD4+ T cells.
Transplantation Antigen
- HLA (Human Leukocyte Antigen) is the transplantation antigen.
CD Molecules
- CD stands for Cluster of Differentiation.
- CD4 is also a receptor for HIV.
- CD molecules are used to identify and classify cell surface molecules on leukocytes.
Immunological Diseases
- Ankylosing spondylitis is associated with HLA B27.
- Note: There is a mistake in the question, it should be HLA B27, not HLA A27.
MHC Restriction
- MHC restriction refers to the requirement for antigen to be recognized in association with MHC molecules.
Test your knowledge of cytokines, antigen presentation, and transplantation antigens in immunology. Learn about IFN, chemokines, MHC classes, and HLA.
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