Immunology Quiz

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Questions and Answers

Which cells present antigens to T cells in the form of peptide:MHC complex?

  • B cells
  • Dendritic cells (correct)
  • Natural killer cells
  • Macrophages

Which type of T cell recognizes peptides from intracellular pathogens that associate with MHC1?

  • CD4 helper T cells
  • Th1 cells
  • Th2 cells
  • CD8 cytotoxic T cells (correct)

Which molecule guides naïve T cells to lymph nodes?

  • L-selectin (correct)
  • CCR7
  • LFA-1
  • ICAM-1

Which cells activate the microbiocidal properties of macrophages and induce B cells to make IgG?

<p>Th1 cells (B)</p> Signup and view all the answers

Which cells recognize peptides from pathogens multiplying in vesicles and ingested pathogens bound to MHC2?

<p>CD4 helper T cells (B)</p> Signup and view all the answers

Which molecule enhances integrin affinity and is found on T cells?

<p>LFA-1 (D)</p> Signup and view all the answers

Which cells ingest antigen and present to T cells, then migrate to lymphoid tissue and express co-stimulatory molecules?

<p>Dendritic cells (B)</p> Signup and view all the answers

Which molecule is expressed by vascular endothelial cells and binds to CCR7 on naïve T cells?

<p>CCL21 (B)</p> Signup and view all the answers

Which type of T cell recognizes peptides from extracellular antigens and can stimulate B cells to produce IgA and IgE?

<p>Th2 cells (B)</p> Signup and view all the answers

Which molecule is expressed as sialyl-LewisX molecules on endothelial venules and interacts with L-selectin on naïve T cells?

<p>GlyCAM-1 (A)</p> Signup and view all the answers

Which cells recognize peptides from pathogens that accumulate in large numbers in macrophages and dendritic cells?

<p>Th1 cells (D)</p> Signup and view all the answers

Which molecule is found on T cells and interacts with ICAM-1 on endothelial cells?

<p>LFA-1 (C)</p> Signup and view all the answers

What do TCRs recognize when presented by MHC on the surface of another cell?

<p>Antigen peptides (A)</p> Signup and view all the answers

Which type of T cells recognize MHC1 and respond to cells infected with pathogens residing in the cytosol?

<p>CD8 cytotoxic T cells (A)</p> Signup and view all the answers

Which type of cells present peptides from the membrane of virus glycoproteins in viral envelope through MHC1?

<p>Infected cells (C)</p> Signup and view all the answers

What type of pathogens or products are recognized by CD4 helper T cells through MHC2?

<p>Pathogens or products that live in vesicles (C)</p> Signup and view all the answers

What is typically derived from viruses that take over the cell's biomachinery to make their own proteins and is presented by MHC1?

<p>Antigen fragments (A)</p> Signup and view all the answers

In addition to proteins made in the cytosol, what else is presented by MHC1 from the virus?

<p>Peptides from the membrane of virus glycoproteins (B)</p> Signup and view all the answers

Which virus prevents the transport of viral peptides into ER by a protein that inhibits TAP, interfering with MHC1:peptide complex being expressed on the cell surface?

<p>Herpes simplex virus (A)</p> Signup and view all the answers

Which virus encodes a protein that binds to MHC1 and retains them in the ER, thereby evading immune recognition?

<p>Adenoviruses (D)</p> Signup and view all the answers

What is typically presented by MHC2 from infected cells?

<p>Peptides from pathogens or products that live in vesicles (C)</p> Signup and view all the answers

Which type of pathogens or products are recognized by CD4 helper T cells through MHC2?

<p>Pathogens or products that live in vesicles (A)</p> Signup and view all the answers

What do antigen fragments that bind MHC1 are typically derived from?

<p>Viruses (D)</p> Signup and view all the answers

What do CD8 cytotoxic T cells respond to?

<p>Cells infected with pathogens that live in the cytosol (A)</p> Signup and view all the answers

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