Immunology Quiz
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Questions and Answers

Which cells present antigens to T cells in the form of peptide:MHC complex?

  • B cells
  • Dendritic cells (correct)
  • Natural killer cells
  • Macrophages
  • Which type of T cell recognizes peptides from intracellular pathogens that associate with MHC1?

  • CD4 helper T cells
  • Th1 cells
  • Th2 cells
  • CD8 cytotoxic T cells (correct)
  • Which molecule guides naïve T cells to lymph nodes?

  • L-selectin (correct)
  • CCR7
  • LFA-1
  • ICAM-1
  • Which cells activate the microbiocidal properties of macrophages and induce B cells to make IgG?

    <p>Th1 cells</p> Signup and view all the answers

    Which cells recognize peptides from pathogens multiplying in vesicles and ingested pathogens bound to MHC2?

    <p>CD4 helper T cells</p> Signup and view all the answers

    Which molecule enhances integrin affinity and is found on T cells?

    <p>LFA-1</p> Signup and view all the answers

    Which cells ingest antigen and present to T cells, then migrate to lymphoid tissue and express co-stimulatory molecules?

    <p>Dendritic cells</p> Signup and view all the answers

    Which molecule is expressed by vascular endothelial cells and binds to CCR7 on naïve T cells?

    <p>CCL21</p> Signup and view all the answers

    Which type of T cell recognizes peptides from extracellular antigens and can stimulate B cells to produce IgA and IgE?

    <p>Th2 cells</p> Signup and view all the answers

    Which molecule is expressed as sialyl-LewisX molecules on endothelial venules and interacts with L-selectin on naïve T cells?

    <p>GlyCAM-1</p> Signup and view all the answers

    Which cells recognize peptides from pathogens that accumulate in large numbers in macrophages and dendritic cells?

    <p>Th1 cells</p> Signup and view all the answers

    Which molecule is found on T cells and interacts with ICAM-1 on endothelial cells?

    <p>LFA-1</p> Signup and view all the answers

    What do TCRs recognize when presented by MHC on the surface of another cell?

    <p>Antigen peptides</p> Signup and view all the answers

    Which type of T cells recognize MHC1 and respond to cells infected with pathogens residing in the cytosol?

    <p>CD8 cytotoxic T cells</p> Signup and view all the answers

    Which type of cells present peptides from the membrane of virus glycoproteins in viral envelope through MHC1?

    <p>Infected cells</p> Signup and view all the answers

    What type of pathogens or products are recognized by CD4 helper T cells through MHC2?

    <p>Pathogens or products that live in vesicles</p> Signup and view all the answers

    What is typically derived from viruses that take over the cell's biomachinery to make their own proteins and is presented by MHC1?

    <p>Antigen fragments</p> Signup and view all the answers

    In addition to proteins made in the cytosol, what else is presented by MHC1 from the virus?

    <p>Peptides from the membrane of virus glycoproteins</p> Signup and view all the answers

    Which virus prevents the transport of viral peptides into ER by a protein that inhibits TAP, interfering with MHC1:peptide complex being expressed on the cell surface?

    <p>Herpes simplex virus</p> Signup and view all the answers

    Which virus encodes a protein that binds to MHC1 and retains them in the ER, thereby evading immune recognition?

    <p>Adenoviruses</p> Signup and view all the answers

    What is typically presented by MHC2 from infected cells?

    <p>Peptides from pathogens or products that live in vesicles</p> Signup and view all the answers

    Which type of pathogens or products are recognized by CD4 helper T cells through MHC2?

    <p>Pathogens or products that live in vesicles</p> Signup and view all the answers

    What do antigen fragments that bind MHC1 are typically derived from?

    <p>Viruses</p> Signup and view all the answers

    What do CD8 cytotoxic T cells respond to?

    <p>Cells infected with pathogens that live in the cytosol</p> Signup and view all the answers

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