Immunology: Parasite Evasion Mechanisms

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18 Questions

What is the role of Th2 lymphocytes in immune response to helminthic infections?

Enhancing the proliferation and differentiation of B-lymphocytes into plasma cells

What is the characteristic immune response observed in most helminthic infections?

Eosinophilia and elevated serum IgE

How do IgE antibodies contribute to the expulsion of adult intestinal helminths?

By binding to mucosal mast cells, eosinophils, and goblet cells

Which mechanism of parasite evasion involves reducing the immune function of macrophages?

Immune suppression

What is the consequence of Trypanosoma gambiense infection on the immune system?

Impaired B and T lymphocyte activities

What is the characteristic immune response observed in filarial infections, such as Wuchereria bancrofti and Brugia malayi?

Polyclonal hypergammaglobulinemia with non-specific antibodies

What type of diet is not suitable for the development of intestinal protozoans?

High-protein

What is the role of pH in non-specific defenses against parasites?

pH kills parasites

Which of the following is an example of a specific immune response?

Triggered by antigens

What is the effect of the Duffy blood factor on Plasmodium vivax infections?

Increases susceptibility

What is the role of the immune response in parasitic infections?

Provides both non-specific and specific defenses

What is the effect of sickle-cell trait on falciparum malaria?

Confers some protection

How do antigens from parasites typically originate?

From the surface, secretions, excretions, and somatic tissues of the parasite

What is the primary function of macrophages in the immune response to parasites?

To serve as the first line cellular defense against invading pathogens through phagocytosis

What type of cells are increased in cases of parasitic invasion?

Eosinophils and neutrophils

What is the role of the skin in the immune response to parasites?

To have cellular components that participate in the immune response

What type of immune response begins when parasitic antigens are processed and presented to T-helper lymphocytes?

Specific immune response

What is the function of T-helper lymphocytes in the immune response to parasites?

To initiate a specific immune response

Learn about the immune responses to helminthic infections, including the role of Th2 lymphocytes, eosinophilia, and IgE antibodies. Understand how parasites evade the immune system and the mechanisms involved.

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