Questions and Answers
Which immunoglobulin isotype does not switch its heavy chain to become another isotype?
What activation factor differentiates naive B cells into IgA-expressing B cells?
How does IgA protect itself from degradation in mucosal fluid?
What mechanism do CD8+ T cells use to recognize virus-infected cells?
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What is the primary role of CD40 activation in antigen-presenting cells (APCs)?
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What process do B cells undergo to increase the affinity maturation of immunoglobulins?
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How do Tfh cells migrate toward follicular tissue to activate B cells?
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What is a key feature of IgE in the immune response?
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Which mechanism is primarily responsible for the switching of immunoglobulin heavy chains?
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What is the specific role of activation-induced deaminase (AID) during H-chain switching?
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Which immunoglobulin isotype is crucial for the elimination of helminths?
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What role does CD8+ T cell play in increasing the number of antigen-specific clones compared to CD4+ T cells during infection?
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Which enzyme is responsible for removing nucleotides from VDJ recombinant in junctional diversity?
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What process do B cells undergo to enhance affinity maturation of immunoglobulin?
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Which immune component is responsible for neutralizing microbes and their toxins?
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Which receptor is involved in the expression of CD28 in T cell activation?
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What is the action mechanism of activation-induced deaminase (AID) in H-chain switching?
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What is the primary role of CD40 activation in antigen-presenting cells (APCs)?
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What is the role of ubiquitin in the class-MHC pathway?
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Which cytotoxic molecule is secreted by cytotoxic T lymphocytes to kill virus-infected cells?
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Why can IgG survive longer compared to other immunoglobulin isotypes?
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Which enzyme plays a key role in immunoglobulin H-chain switching?
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During infection, why do antigen-specific clones of CD8+ T cells increase in number more than CD4+ T cells?
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Which of the following describes the function of MHC molecules?
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How do neonates primarily protect themselves from infections?
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Which Ig isotype is produced through T-independent activation of B cells?
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What factor must activate naive B cells to differentiate into IgA-expressing B cells?
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Which type of T helper cell is important in selecting specific Ig-producing B cells in the germinal center?
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What characteristic allows IgG to survive longer compared to other Ig isotypes?
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What role do the complement proteins C3a and C5a play in the immune response?
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Which cytotoxic molecule do cytotoxic T lymphocytes secrete to eliminate virus-infected cells?
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Which receptor complex is primarily involved in recognizing pathogen-associated molecular patterns?
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What is the primary function of the enzyme Ligas during VDJ recombination?
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Which B cell subset is specifically involved in somatic hypermutation?
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How do CD8+ T cells primarily differ in their effector function from CD4+ Th cells?
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What role does ubiquitin play in the class-MHC pathway?
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What is the primary purpose of forming the membrane attack complex (MAC) during complement activation?
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What action mechanism is performed by activation-induced deaminase (AID) during heavy chain switching?
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Among the five immunoglobulin (Ig) isotypes, which one does NOT switch its heavy chain to become another Ig isotype?
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