Immunology Basics

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12 Questions

What is the main difference between an immunogen and an antigen?

Immunogens induce an immune response while antigens are recognized by the immune system.

What is the role of an epitope in the immune response?

Epitopes are recognized by the B cell or T cell in an antigen.

Why might a human body reject a transplanted pig's heart according to the text?

Because pig hearts are genetically different from humans.

What property of an antigen makes it immunogenic according to the text?

Chemical composition and complexity.

In what scenario can a hapten induce an immune response?

When it is bound to a carrier molecule.

Why might one person have a hypersensitivity reaction to a substance while another does not?

Because not all people have similar genetic compositions.

What type of antigen is generally considered to be the most immunogenic?

Proteins

Which statement regarding antigen size and immunogenicity is true?

High molecular weight antigens may lose immunogenicity if they break up into smaller molecules in the body.

Which organ is NOT considered a central (primary) lymphoid organ in the immune system?

Spleen

Why might one need a smaller amount of antigen if it is a protein compared to a polysaccharide to induce an immune response?

Proteins have larger molecular sizes than polysaccharides.

In which mode of administration might an antigen provoke a better immune response compared to intramuscular injection?

Intradermal injection

Why might antigens lose their immunogenicity even if they have high molecular weights?

Some high molecular weight antigens break up into smaller molecules in the body.

Test your knowledge on key concepts in immunology such as immunogen, antigen, epitope, and hapten. Learn about the immune system and immune responses.

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