15 Questions
What is the primary function of a B-cell in the immune response?
To present antigens to T H cells
Which type of immunity is involved in the interaction between B cells and T H cells?
Humoral immunity
What is the term for the region on an antigen that is recognized by a T cell receptor?
Epitope
What type of MHC molecule is involved in the presentation of antigens by B cells to T H cells?
MHC-II
What is the term for cells that can internalize, process, and present antigens to T cells?
Antigen-presenting cells
Which type of MHC is expressed on all nucleated cells?
MHC I
What is the primary function of MHC II?
To present antigen to CD4+ T cells
What is the result of the presence of foreign antigens on a cell that expresses MHC I?
The cell is targeted for destruction by CD8+ T cells
What is the unique characteristic of each lymphocyte?
It recognizes and responds to a single epitope
What is the role of CD4 on TH cells?
It binds to MHC II on antigen-presenting cells
What is the primary difference between classical antigens and superantigens?
The requirement for antigen-presenting cells
Which type of antigen requires antigen-presenting cells (APCs) to process and present epitopes?
Only classical antigens
What is the role of MHC-II molecules in the immune response?
To present antigens to T-cells
Which of the following is a characteristic of superantigens?
They bind directly to MHC-II molecules
What is the main difference between MHC-II restriction and classical antigen presentation?
The requirement for antigen-presenting cells
Understanding the roles of MHC I and MHC II in the immune system, including antigen presentation to T-cells and activation of immune responses.
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