Immunological Memory and Vaccination Chapter 11
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Questions and Answers

What can occur when antibodies from a primary exposure to a dengue virus serotype bind to a different serotype during a second exposure?

  • Antibody-dependent enhancement (ADE) (correct)
  • Neutralization of the virus
  • Elimination of macrophages
  • Production of more neutralizing antibodies

What is a benefit of DNA and mRNA vaccines?

  • They are only effective in elderly individuals
  • They can bypass the lengthy process of traditional vaccine development (correct)
  • They are only effective against a single serotype of a virus
  • They require a lengthy process of traditional vaccine development

What is the mechanism by which macrophages take up the virus in antibody-dependent enhancement (ADE)?

  • Via the T-cell receptor
  • Via the B-cell receptor
  • Via the Fc receptor (correct)
  • Via the MHC receptor

What is a safety concern associated with DNA and mRNA vaccines?

<p>They have serious safety concerns (B)</p> Signup and view all the answers

What type of vaccine introduces the genetic material for making immunogenic viral proteins directly into the host?

<p>DNA vaccine (C)</p> Signup and view all the answers

Which of the following vaccines is an example of an mRNA vaccine?

<p>Pfizer Moderna (D)</p> Signup and view all the answers

What type of vaccine is developed by Astra-Zeneca?

<p>Adenovirus vaccine (C)</p> Signup and view all the answers

What is the name of the receptor involved in antibody-dependent enhancement (ADE)?

<p>Fc receptor (C)</p> Signup and view all the answers

What is a result of antibody-dependent enhancement (ADE)?

<p>Severe disease (B)</p> Signup and view all the answers

Which of the following vaccines is an example of an inactivated coronavirus vaccine?

<p>Sinopharm (B)</p> Signup and view all the answers

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