Immunohematology-Blood Banking: Basic Principles of Immunology and AG-AB Reactions

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12 Questions

Which type of antibodies is typically produced in response to red cell antigen stimulation?

Immune antibodies

What is the characteristic of antibodies associated with hemolytic transfusion reactions, hemolytic disease of the newborn, and autoimmune hemolytic anemia?

Clinically significant antibodies

Which blood group antigen is directly related to glycophorin?

MNS

What is the molecular size requirement for antigens present on red blood cells?

Sufficient molecular size

Which type of antibody is usually produced in response to environmental antigens like bacteria and pollen?

Naturally occurring antibodies

What is the characteristic feature of irregular antibodies in a patient's serum?

Present in a very small human population only

What is the main difference between an antigen and an immunogen?

Immunogens trigger an immune response.

Which term describes an incomplete antigen that can react with specific antibodies but is not immunogenic?

Hapten

What is the role of an epitope in an antigen molecule?

Confers specificity to the antigen

Where are blood group antigens mainly distributed in the body?

Throughout tissues, white cells, and platelets

Why are ABH antigens in tissues important for organ transplants?

They determine tissue compatibility

What can happen to a hapten to make it immunogenic?

It can bind with a schlepper molecule

This quiz covers the fundamental principles of immunology and antigen-antibody reactions, distinguishing between antigens and immunogens. It also discusses the properties of antigens and the immune response triggered by immunogens in the host.

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