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Questions and Answers
What is the consequence of T cells recognizing self antigen without costimulatory molecules?
What is the consequence of T cells recognizing self antigen without costimulatory molecules?
- They differentiate into memory cells
- They become activated effector cells
- They downregulate PD-1 expression
- They turn on pro-apoptotic proteins (correct)
How do tolerant T cells eliminate long-exposed antigens?
How do tolerant T cells eliminate long-exposed antigens?
- By upregulating PD-1 expression
- By rapid proliferation of memory cells
- By activating effector T cells
- Through an innate immune response (correct)
What is the mechanism by which activated T cells start killing each other?
What is the mechanism by which activated T cells start killing each other?
- Upregulation of PD-1
- Downregulation of Fas Ligand
- Fas-Fas Ligand pathway (correct)
- Overexpression of costimulatory molecules
Why does an antigen persisting for a long time lead to the exhaustion of T cell clones?
Why does an antigen persisting for a long time lead to the exhaustion of T cell clones?
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What is the role of PD-1 in the context of persistent antigens?
What is the role of PD-1 in the context of persistent antigens?
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In which scenario do we witness the depletion of memory cells, tolerance, or immunosuppression?
In which scenario do we witness the depletion of memory cells, tolerance, or immunosuppression?
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What happens when T cells receive signals from T regulatory cells?
What happens when T cells receive signals from T regulatory cells?
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