18 Questions
What is the main function of histamine released by mast cells?
Inducing vasodilation
Which of the following is NOT part of the vascular response associated with inflammation?
Rubella
What is the role of chemokines released by resident macrophages and mast cells during an infection?
Causing vasodilation and enhancing chemotaxis
Which type of immune cells are mainly responsible for phagocytosing microbes in the body?
Neutrophils
Which Toll-like receptor is specifically associated with detecting gram-negative bacteria?
TLR-4
What is the initial stage involved in phagocytosis where immune cells are attracted to the site of infection?
Chemotaxis
What is the main reason for vasodilation during inflammation?
Release of histamine from injured mast cells
What is the main factor that prevents natural killer (NK) cells from killing healthy cells?
MHC class I
Which of the following is NOT a symptom associated with the vascular response during inflammation?
Pallor
In which scenario will NK cells automatically eliminate MHC class I from the cells?
When cells are infected with pathogens
What is the purpose of chemotaxis during the cellular response in inflammation?
To attract white blood cells to the site of injury
What is the mechanism of action in Antibody-Dependent Cell Cytotoxicity (ADCC) by NK cells?
Release of perforins and granzymes
Which process involves the migration of white blood cells from blood vessels to the tissue?
Diapedesis
Which type of immunity is characterized by acquired exposure to pathogens and memory of prior exposure?
Adaptive immunity
What is responsible for the clearance of the affected area during phagocytosis in inflammation?
Migration of macrophages
What is the key cell involved in the adaptive immune response?
Lymphocyte
Which mediator plays a key role in causing vasodilation during inflammation?
Histamine
What differentiates lymphocytes from other white blood cells?
They arise from a hematopoietic stem cell
Test your knowledge on the immune system response mechanisms including phagocytosis, histamine release, vascular response, and Toll-like receptors. Explore how dendritic cells and macrophages play a crucial role in activating the adaptive immune system.
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