Phagocytosis and the Immune System

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Which of the following is a key component of the second line of defense in the immune system?

Phagocytosis

What is the main function of phagocytes in the immune system?

Ingest and destroy microorganisms

Which of the following is NOT a type of phagocyte?

T cells

What happens when a phagocyte approaches a bacteria during phagocytosis?

Attachment of non-specific receptors to bacterial antigen

What role does phagocytosis play in the adaptive immune system?

Processing and presenting antigens

What are the cells called that engulf pathogens and present antigens to the adaptive immune system?

Antigen presenting cells

Which cells are highly phagocytic?

Neutrophils and monocytes

What is the mechanism through which phagocytosis occurs?

Phagocyte approaches a bacteria – attachment of non-specific receptors to bacterial antigen – extends pseudopods around the bacteria – releases enzymes from lysosome to digest bacteria - release of end product

What are the peptides called that are recognized by cells of the adaptive immune system as antigens?

Peptides from processed pathogens

Study Notes

Phagocytosis and Immune System

  • Phagocytes are a key component of the second line of defense in the immune system.
  • The main function of phagocytes is to engulf and digest foreign particles and microorganisms.
  • Lymphocytes are NOT a type of phagocyte.
  • When a phagocyte approaches a bacterium during phagocytosis, the bacterium is engulfed by the phagocyte's plasma membrane, and a phagosome is formed.
  • Phagocytosis plays a crucial role in the adaptive immune system by presenting antigens to T-cells, leading to an immune response.
  • The cells that engulf pathogens and present antigens to the adaptive immune system are called Antigen-Presenting Cells (APCs).
  • Neutrophils and macrophages are highly phagocytic cells.
  • Phagocytosis occurs through the mechanism of receptor-mediated endocytosis, where the phagocyte's surface receptors recognize and bind to the pathogen, leading to its engulfment.
  • The peptides recognized by cells of the adaptive immune system as antigens are called epitopes.

Test your knowledge on the process of phagocytosis and its role in the immune system. Learn about the different types of phagocytes and the steps involved in this crucial defense mechanism.

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