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Questions and Answers
Which type of gene mutation is more frequently associated with immune deficiency?
Which type of gene mutation is more frequently associated with immune deficiency?
- Mutations in autosomal genes
- Mutations in recessive genes
- Mutations in X-linked genes (correct)
- Mutations in dominant genes
Which type of mutation in the RAG1 or RAG2 genes can lead to a disorder called Omenn syndrome?
Which type of mutation in the RAG1 or RAG2 genes can lead to a disorder called Omenn syndrome?
- Complete loss-of-function mutation
- Dominant mutation
- Recessive mutation
- Hypomorphic mutation (correct)
Which set of genes contribute to susceptibility to herpes simplex virus infection of the brain (encephalitis)?
Which set of genes contribute to susceptibility to herpes simplex virus infection of the brain (encephalitis)?
- Genes affecting interleukin-12 (IL-12)
- Genes affecting Th1 cell development
- Genes affecting Toll-like receptor 3 (TLR3) (correct)
- Genes affecting complement proteins
Which component of the immune system is affected in congenital deficiencies causing autoimmune diseases?
Which component of the immune system is affected in congenital deficiencies causing autoimmune diseases?
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Which of the following is a consequence of defective immunity?
Which of the following is a consequence of defective immunity?
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Which type of immunodeficiency results from genetic defects?
Which type of immunodeficiency results from genetic defects?
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What is the estimated prevalence of congenital immune deficiencies in the United States and Europe?
What is the estimated prevalence of congenital immune deficiencies in the United States and Europe?
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