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Immune System Defects Quiz
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Immune System Defects Quiz

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Questions and Answers

Which type of gene mutation is more frequently associated with immune deficiency?

  • Mutations in autosomal genes
  • Mutations in recessive genes
  • Mutations in X-linked genes (correct)
  • Mutations in dominant genes

    • Which type of mutation in the RAG1 or RAG2 genes can lead to a disorder called Omenn syndrome?

  • Complete loss-of-function mutation
  • Dominant mutation
  • Recessive mutation
  • Hypomorphic mutation (correct)

    • Which set of genes contribute to susceptibility to herpes simplex virus infection of the brain (encephalitis)?

  • Genes affecting interleukin-12 (IL-12)
  • Genes affecting Th1 cell development
  • Genes affecting Toll-like receptor 3 (TLR3) (correct)
  • Genes affecting complement proteins

    • Which component of the immune system is affected in congenital deficiencies causing autoimmune diseases?

    <p>Self-tolerance</p> Signup and view all the answers

    Which of the following is a consequence of defective immunity?

    <p>Increased susceptibility to infections and cancers</p> Signup and view all the answers

    Which type of immunodeficiency results from genetic defects?

    <p>Congenital immunodeficiencies</p> Signup and view all the answers

    What is the estimated prevalence of congenital immune deficiencies in the United States and Europe?

    <p>1 in 500 individuals</p> Signup and view all the answers

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