18 Questions
Which type of phagocytic cell is responsible for early phagocytosis during an infection, before antibodies are available?
Phagocytosis can occur in the absence of serum antibodies
What is an important function of the spleen?
Filtering microorganisms from the bloodstream
What is the most common bacterial infection that patients without a functional spleen are susceptible to?
Pneumococci
Which of the following is NOT a type of phagocytic cell in the immune system?
Lymphocytes
What is the main consequence of the bone marrow being suppressed, leading to a decrease in the number of functional granulocytes?
Increased susceptibility to opportunistic infection by bacteria
Which of the following components is NOT found in granulocyte granules?
Antibodies
Which of the following is the main function of phagocytic cells during infections?
Chemotaxis, migration, ingestion and microbial killing
Which type of phagocytic cell is primarily responsible for clearing particulate matter from the lymph and bloodstream?
Mononuclear phagocytic cells
What is the primary role of the spleen in the immune system?
Filtering the blood and removing old/damaged red blood cells
Which type of phagocytic cell is the first to respond to a bacterial infection, and is crucial for the initial clearance of the pathogen?
Neutrophils
Which type of phagocytic cell is responsible for the production of inflammatory mediators, such as leukotrienes and prostaglandins, during an immune response?
Eosinophils
Which of the following is a characteristic of the innate immune system's pattern recognition receptors (PRRs)?
They recognize pathogen-associated molecular patterns (PAMPs)
What is the main function of opsonins in phagocytosis?
Facilitate ingestion by phagocytes
Which type of immune cell is primarily responsible for the process known as degranulation?
Granulocytes
What factor contributes to the inhibition of phagocytic mechanisms in the pathogenesis of legionella pneumonia?
Prevention of degranulation
How do activated macrophages contribute to inflammation?
Produce and release interleukin-1
Which immune cell is derived from monocyte stem cells in the bone marrow?
Macrophages
What is the primary effect of ingestion of foreign particles on phagocytic granulocytes?
Formation of phagolysosome
Test your knowledge on immune system cells such as Kupffer cells and macrophages, and their role in phagocytosis. Learn about the function of the spleen in filtering microorganisms from the bloodstream and the consequences of spleen removal or nonfunctionality on bacterial sepsis susceptibility.
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