Immune System and Transplantation Quiz
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Questions and Answers

Which of the following is the correct statement about MHC genes?

  • MHC genes are not highly polymorphic.
  • Two unrelated individuals are very unlikely to express several HLA proteins that are different from each other.
  • The human MHC is called the human leukocyte antigen (HLA) complex. (correct)
  • MHC genes are not present in all mammals.
  • What is the function of MHC molecules?

  • To produce cytokines for immune response.
  • To display peptide antigens for recognition by B lymphocytes.
  • To produce antibodies against foreign antigens.
  • To display peptide antigens for recognition by T lymphocytes. (correct)
  • What is the chance that two siblings will have the same MHC alleles?

  • 1 in 5
  • 1 in 4 (correct)
  • 1 in 2
  • 1 in 3
  • Which of the following is a reason why recognition of allogeneic MHC molecules results in strong T cell reactions?

    <p>Many clones of T cells that are specific for different foreign peptides bound to the same self MHC molecule may cross-react with any one allogeneic MHC molecule.</p> Signup and view all the answers

    Which of the following is true about the process of negative selection in the thymus?

    <p>It eliminates cells that strongly recognize self MHC.</p> Signup and view all the answers

    What is the difference between allorecognition and recognition of infected cells?

    <p>Allorecognition results in strong T cell reactions, while recognition of infected cells usually elicits weaker reactions.</p> Signup and view all the answers

    What are non-MHC antigens that induce graft rejection called?

    <p>Minor histocompatibility antigens</p> Signup and view all the answers

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