Immune System and Transplantation Quiz

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Questions and Answers

Which of the following is the correct statement about MHC genes?

MHC genes are not highly polymorphic.
Two unrelated individuals are very unlikely to express several HLA proteins that are different from each other.
The human MHC is called the human leukocyte antigen (HLA) complex. (correct)
MHC genes are not present in all mammals.

What is the function of MHC molecules?

To produce cytokines for immune response.
To display peptide antigens for recognition by B lymphocytes.
To produce antibodies against foreign antigens.
To display peptide antigens for recognition by T lymphocytes. (correct)

What is the chance that two siblings will have the same MHC alleles?

1 in 5
1 in 4 (correct)
1 in 2
1 in 3

Which of the following is a reason why recognition of allogeneic MHC molecules results in strong T cell reactions?

Many clones of T cells that are specific for different foreign peptides bound to the same self MHC molecule may cross-react with any one allogeneic MHC molecule. (A) Signup and view all the answers

Which of the following is true about the process of negative selection in the thymus?

It eliminates cells that strongly recognize self MHC. (B) Signup and view all the answers

What is the difference between allorecognition and recognition of infected cells?

Allorecognition results in strong T cell reactions, while recognition of infected cells usually elicits weaker reactions. (D) Signup and view all the answers